Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   OG331_RS22335 Genome accession   NZ_CP108683
Coordinates   4931731..4932855 (+) Length   374 a.a.
NCBI ID   WP_328425026.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_01017     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4926731..4937855
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG331_RS22320 (OG331_22145) - 4927353..4928219 (+) 867 WP_406198923.1 hypothetical protein -
  OG331_RS22325 (OG331_22150) - 4928242..4930029 (-) 1788 WP_406198925.1 BACON domain-containing protein -
  OG331_RS22330 (OG331_22155) radA 4930240..4931649 (+) 1410 WP_406198927.1 DNA repair protein RadA Machinery gene
  OG331_RS22335 (OG331_22160) disA 4931731..4932855 (+) 1125 WP_328425026.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  OG331_RS22340 (OG331_22165) - 4933068..4933877 (-) 810 WP_406198929.1 hypothetical protein -
  OG331_RS22345 (OG331_22170) - 4934063..4934695 (+) 633 WP_406198931.1 phosphatase PAP2 family protein -
  OG331_RS22350 (OG331_22175) - 4934699..4935358 (-) 660 WP_406198933.1 response regulator -
  OG331_RS22355 (OG331_22180) - 4935411..4936946 (-) 1536 WP_406198935.1 sensor histidine kinase -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40083.83 Da        Isoelectric Point: 5.0029

>NTDB_id=665129 OG331_RS22335 WP_328425026.1 4931731..4932855(+) (disA) [Streptomyces sp. NBC_01017]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGSDKTVEVMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGHRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALYELDALTHAELLELSTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=665129 OG331_RS22335 WP_328425026.1 4931731..4932855(+) (disA) [Streptomyces sp. NBC_01017]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGCTCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCCGTGGCACCCGGCACGGCCCTGCGCGACGGGCTTGAGCGGATCCTCCGCGGCAACACCGGCGGACTCATCGTGC
TCGGCTCCGACAAGACCGTCGAGGTGATGTGCACGGGCGGATTCGTCCTGGATGTCGAGTTCACGGCGACGCGGCTGCGT
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTGTCGTCGGATCTGTCGAAGATCCTGCGCGCCGGCGTCCAGCTGGTCCC
GGACCCGACGATCCCCACCGAGGAGACGGGCACCCGGCACCGCACGGCGGACCGGGTCAGCAAGCAGGTCGGCTTCCCGG
TCGTCTCGGTCTCCCAGTCCATGCGGCTGATCGCGCTCTACGTCGACGGCCACCGCCGTGTCCTGGAGGACTCGGCGGCG
ATCCTCTCCCGCGCCAACCAGGCCCTGGCGACCCTGGAGCGCTACAAGCTCCGCCTCGACGAGGTCGCGGGAACGTTGTC
AGCGCTGGAGATCGAGGACCTGGTGACGGTCCGCGACGTCTCGGCGGTCGCCCAGCGCCTGGAGATGGTCCGGCGCATCG
CGACCGAGATCGCCGAGTACGTGGTGGAGCTCGGCACCGACGGACGTCTCCTGGCCCTTCAGCTGGACGAATTGATCGCG
GGCGTGGAGCCCGAGCGCGAGCTCGTGGTGCGGGACTACGTCCCCGAGCCGACGGCGAAGCGTTCCCGCACGGTCGACGA
GGCGCTGTACGAGCTGGACGCGCTCACCCACGCCGAGCTTCTCGAACTTTCCACGGTGGCAAGGGCGTTGGGCTACACCG
GCTCCCCGGAGGCGCTGGACTCCGCGGTCTCCCCGCGCGGCTTCCGCCTCCTGGCCAAGGTGCCGAGGCTGCCGGGCGCG
ATCATCGACCGCCTGGTGGAGCACTTCGGCGGCCTGCAGAAGCTGCTCGCCGCGAGCGTGGACGACCTCCAGACGGTGGA
CGGCGTCGGCGAGGCCCGGGCGCGCAGCGTCCGTGAGGGCCTGTCGCGGTTGGCGGAGAGCTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.706

96.524

0.441