Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   MOV58_RS00195 Genome accession   NZ_CP093539
Coordinates   42422..43771 (-) Length   449 a.a.
NCBI ID   WP_227967764.1    Uniprot ID   -
Organism   Staphylococcus hominis strain C5     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 34066..42367 42422..43771 flank 55


Gene organization within MGE regions


Location: 34066..43771
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MOV58_RS00155 (MOV58_00155) mecA 34066..36075 (-) 2010 WP_063852655.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  MOV58_RS00160 (MOV58_00160) - 36172..37158 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  MOV58_RS00165 (MOV58_00165) - 37130..37390 (+) 261 WP_001549961.1 type I restriction enzyme endonuclease domain-containing protein -
  MOV58_RS00170 (MOV58_00170) - 37381..38988 (-) 1608 Protein_31 IS1182 family transposase -
  MOV58_RS00175 (MOV58_00175) - 39040..39546 (-) 507 WP_001092195.1 DUF1643 domain-containing protein -
  MOV58_RS00180 (MOV58_00180) - 39561..39872 (-) 312 WP_001024803.1 DUF960 family protein -
  MOV58_RS00185 (MOV58_00185) - 39959..40309 (-) 351 WP_000859157.1 SAUGI family uracil-DNA glycosylase inhibitor -
  MOV58_RS00190 (MOV58_00190) ccrB 40775..42400 (-) 1626 WP_145462987.1 recombinase family protein Machinery gene
  MOV58_RS00195 (MOV58_00195) ccrA 42422..43771 (-) 1350 WP_227967764.1 recombinase family protein Machinery gene

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52542.42 Da        Isoelectric Point: 10.1566

>NTDB_id=665074 MOV58_RS00195 WP_227967764.1 42422..43771(-) (ccrA) [Staphylococcus hominis strain C5]
MKQAMGYLRQSTTKQQSLAVQKQAIKTLAEKHNIQHITFYSDKQSGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVSNGIKEKARQGKLITTHAPFGYHYK
RGTFTINKNESPTVIAVFNYYLQGNGYKKITQFLEEDNKLLNRKPYQVRNIIMNPNYCGRVINKYGQYDNMFPSIVSTNM
YEQAQALRSQKQIKRTPSDNQLKQKIKCPYCGSKLTNMTIRKGTHSLRYYVCPRNMNESRFVCDFKGINAQELETSVLTT
CQDFFQNQQLYSKINQTIQKQLKNQRDIETKNTLNHEQLIEKLAKGKIDAETFREQTQLLRQQSKPISSINAYQIKRTFQ
NVIKQRFTLNMLYPYIDEIHITKKKILVGIYFKNEPLNIINQTTQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=665074 MOV58_RS00195 WP_227967764.1 42422..43771(-) (ccrA) [Staphylococcus hominis strain C5]
ATGAAACAAGCAATGGGTTACTTACGACAGAGCACTACAAAGCAACAATCCCTAGCAGTACAGAAACAAGCCATCAAGAC
ATTAGCTGAAAAACACAATATTCAACACATCACATTTTATAGCGATAAGCAATCAGGACGCACTGATAAGCGGAATGGTT
ATCAACAAATTACTGAACTGATTCAACAAGGACAATGTGACGTACTATGTTGCTATCGTCTGAATCGACTTCATCGTAAT
TTGAAAAATGCATTAAAACTCATGAAATTGTGCCAAAAATATCATGTTCATATCTTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCATTCGATCGGCTTAAACTTAATATTTTCATCAGCTTGGCCGAATTAGAATCTGATAATATTGGCGAAC
AAGTAAGCAACGGGATAAAAGAAAAAGCGCGTCAGGGTAAATTGATAACTACACACGCCCCCTTTGGTTACCACTACAAA
CGTGGTACATTCACGATAAATAAGAATGAATCACCAACGGTAATTGCCGTATTCAATTACTATCTTCAAGGTAATGGCTA
TAAAAAAATTACACAGTTCTTAGAAGAAGATAACAAACTACTCAACCGGAAACCTTATCAAGTACGTAATATTATTATGA
ATCCCAATTACTGTGGTCGTGTTATCAATAAATATGGACAATATGACAACATGTTTCCGTCTATTGTTTCTACAAATATG
TACGAACAAGCGCAAGCTCTACGATCGCAAAAACAAATCAAACGAACACCTTCAGACAATCAACTCAAACAAAAAATCAA
ATGCCCCTACTGTGGATCTAAACTTACCAATATGACCATTAGAAAAGGGACGCATTCATTACGTTACTATGTCTGCCCAA
GAAATATGAATGAATCACGTTTTGTTTGTGACTTCAAAGGCATCAATGCACAAGAATTAGAAACAAGTGTTTTAACGACT
TGTCAGGACTTCTTTCAGAACCAACAGCTGTACTCAAAAATCAACCAAACAATTCAAAAACAACTCAAAAACCAAAGAGA
CATAGAAACCAAAAATACACTAAACCATGAACAGCTGATAGAAAAATTAGCCAAAGGCAAAATTGATGCAGAAACGTTCA
GAGAACAAACGCAATTATTACGTCAACAATCTAAACCTATATCGTCAATCAATGCATATCAAATTAAAAGGACTTTTCAA
AACGTCATTAAACAACGTTTCACGTTAAACATGTTATACCCTTATATTGATGAAATTCATATCACAAAAAAGAAAATACT
TGTTGGCATTTATTTCAAAAATGAACCTTTAAACATAATCAATCAAACTACGCAATCATCGATTGCTTAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(169-250)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

83.519

100

0.835
  ccrA Staphylococcus aureus N315

76.169

100

0.762