Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MNY58_RS04800 Genome accession   NZ_CP093217
Coordinates   1038120..1038749 (+) Length   209 a.a.
NCBI ID   WP_099090436.1    Uniprot ID   A0A2C6VGX7
Organism   Staphylococcus edaphicus strain CCM 8731     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1033120..1043749
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MNY58_RS04770 (MNY58_04770) - 1033158..1033877 (+) 720 WP_099090430.1 glutamine amidotransferase -
  MNY58_RS04775 (MNY58_04775) - 1033967..1034953 (-) 987 WP_099090431.1 aromatic acid exporter family protein -
  MNY58_RS04780 (MNY58_04780) map 1035130..1035882 (+) 753 WP_099090432.1 type I methionyl aminopeptidase -
  MNY58_RS04785 (MNY58_04785) - 1035986..1036372 (+) 387 WP_099090433.1 hypothetical protein -
  MNY58_RS04790 (MNY58_04790) liaF 1036389..1037090 (+) 702 WP_099090434.1 cell wall-active antibiotics response protein LiaF -
  MNY58_RS04795 (MNY58_04795) vraS 1037087..1038130 (+) 1044 WP_099090435.1 sensor histidine kinase Regulator
  MNY58_RS04800 (MNY58_04800) vraR 1038120..1038749 (+) 630 WP_099090436.1 response regulator transcription factor Regulator
  MNY58_RS04805 (MNY58_04805) - 1038888..1040052 (-) 1165 Protein_944 YihY/virulence factor BrkB family protein -
  MNY58_RS04810 (MNY58_04810) - 1040456..1040740 (-) 285 WP_099090438.1 hypothetical protein -
  MNY58_RS04815 (MNY58_04815) - 1040747..1041211 (-) 465 WP_099090439.1 low molecular weight protein-tyrosine-phosphatase -
  MNY58_RS04820 (MNY58_04820) - 1041346..1041549 (+) 204 WP_099090440.1 DUF1128 family protein -
  MNY58_RS04825 (MNY58_04825) - 1041563..1042801 (+) 1239 WP_099090441.1 aminopeptidase -
  MNY58_RS04830 (MNY58_04830) - 1043029..1043550 (+) 522 WP_099090442.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23691.22 Da        Isoelectric Point: 4.7892

>NTDB_id=662605 MNY58_RS04800 WP_099090436.1 1038120..1038749(+) (vraR) [Staphylococcus edaphicus strain CCM 8731]
MPIKVLFVDDHEMVRIGISSYLSTQADIDVVGEGKSGKDAIEKAHELKPDLILMDLLMDDMDGVEATEQVKKDLPHIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYNNESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=662605 MNY58_RS04800 WP_099090436.1 1038120..1038749(+) (vraR) [Staphylococcus edaphicus strain CCM 8731]
ATGCCAATTAAAGTATTATTTGTTGATGATCATGAAATGGTTCGAATAGGTATTTCTAGTTATTTATCTACGCAAGCAGA
TATCGATGTTGTAGGGGAAGGTAAGTCCGGCAAAGATGCAATTGAAAAAGCACATGAACTAAAACCAGACTTAATCTTAA
TGGACCTACTTATGGATGATATGGATGGTGTCGAAGCTACAGAACAAGTAAAAAAAGACTTACCACATATTAAAGTCGTC
ATGCTGACTAGTTACATTGAAGATAATGAAGTGTATCGTGCACTAGATTCGGGTGTAGATAGCTATATATTAAAAACAAC
AAGTGCAAGTGATATTGCAGAAGCGATTCGTAAGACCTATAATAATGAGTCTGTATTTGAAGCAGAAGTATTAGTTAAAA
TGAGAAACAGAATGAAACAACGTGCGGAACTTTATGAAATGTTAACAGAGCGAGAAATGGAAATATTGCTGTTGATTGCT
AAAGGTTACTCAAACCAAGAGATAGCAAGTGCTTCTCATATAACGATTAAGACAGTTAAAACGCATGTGAGTAACATCTT
AAGTAAACTAGAAGTTCAAGACAGAACCCAAGCCGTTATATATGCATTCCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2C6VGX7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

89.474

100

0.895