Detailed information NTG0662604

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MNY58_RS04795
• Genome accession: NZ_CP093217
• Coordinates: 1037087..1038130 (+)
• Length: 347 a.a.
• NCBI ID: WP_099090435.1
• Uniprot ID: A0A2C6WKA0
• Organism: Staphylococcus edaphicus strain CCM 8731
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1032087..1043130

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MNY58_RS04770 (MNY58_04770)	-	1033158..1033877 (+)	720	WP_099090430.1	glutamine amidotransferase	-
MNY58_RS04775 (MNY58_04775)	-	1033967..1034953 (-)	987	WP_099090431.1	aromatic acid exporter family protein	-
MNY58_RS04780 (MNY58_04780)	map	1035130..1035882 (+)	753	WP_099090432.1	type I methionyl aminopeptidase	-
MNY58_RS04785 (MNY58_04785)	-	1035986..1036372 (+)	387	WP_099090433.1	hypothetical protein	-
MNY58_RS04790 (MNY58_04790)	liaF	1036389..1037090 (+)	702	WP_099090434.1	cell wall-active antibiotics response protein LiaF	-
MNY58_RS04795 (MNY58_04795)	vraS	1037087..1038130 (+)	1044	WP_099090435.1	sensor histidine kinase	Regulator
MNY58_RS04800 (MNY58_04800)	vraR	1038120..1038749 (+)	630	WP_099090436.1	response regulator transcription factor	Regulator
MNY58_RS04805 (MNY58_04805)	-	1038888..1040052 (-)	1165	Protein_944	YihY/virulence factor BrkB family protein	-
MNY58_RS04810 (MNY58_04810)	-	1040456..1040740 (-)	285	WP_099090438.1	hypothetical protein	-
MNY58_RS04815 (MNY58_04815)	-	1040747..1041211 (-)	465	WP_099090439.1	low molecular weight protein-tyrosine-phosphatase	-
MNY58_RS04820 (MNY58_04820)	-	1041346..1041549 (+)	204	WP_099090440.1	DUF1128 family protein	-
MNY58_RS04825 (MNY58_04825)	-	1041563..1042801 (+)	1239	WP_099090441.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40026.57 Da
• Isoelectric Point: 6.7780

>NTDB_id=662604 MNY58_RS04795 WP_099090435.1 1037087..1038130(+) (vraS) [Staphylococcus edaphicus strain CCM 8731]
MNHYFRAIGSMLILVYSTFFAIFFIDKVFVNIMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELKAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVVHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTVELFNREAYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSYAN

Nucleotide

• Length: 1044 bp

>NTDB_id=662604 MNY58_RS04795 WP_099090435.1 1037087..1038130(+) (vraS) [Staphylococcus edaphicus strain CCM 8731]
ATGAATCACTATTTTAGAGCAATAGGGTCTATGTTGATATTAGTTTATAGCACATTTTTTGCCATATTCTTTATTGATAA
AGTGTTTGTAAATATAATGTATTTTCAAGGTATGTTTTATACTCAAATATTTGGCATACCGGTGTTACTATTTTTAAATT
TAATGGTGATATTGCTTTGTATTATTGTAGGTTCTGTATTAGCTTATAAAATTAATCAGCAAAATCATTGGTTAAAAGAT
CAAATTGAGCGTTCAATAGAAGGTCAAACGGTAGGTATCAATGATCAAAATATTGAATTGTATAATGAAACAATCGAATT
ATATCAAACATTAGTGCCTTTAAATCAAGAAGTACATAAGTTGAGAATGAAGACGCAAAACTTAACAAATGAATCATATA
ATATCAATGATGTTAAAGTTAAGAAAATCATAGAAGATGAACGACAACGTTTAGCACGTGAATTACATGACTCAGTTAGT
CAACAACTATTCGCAGCTAGTATGATGTTATCTGCAATTAAAGAGACTGAATTAAAAGCTCCCTTAGACCAACAAATACC
GGTATTAGAAAAAATGATTCAGGATTCACAACTAGAGATGAGGGCGTTGCTGTTACACTTAAGACCTATTGGCTTGAAAG
ATAAATCATTAGGTGAGGGTATTAAAGACTTGGTTGTTGATTTACAGAAAAAAGTACCAATGAAAGTTGTTCATGATATT
GAAGAATTTAAAGTGCCAAAGGGTATAGAAGATCATTTATTTCGTATTACTCAAGAAGCGATTTCGAATACTTTACGACA
TTCTAAAGGGACGAAAGTCACTGTTGAATTATTTAATAGAGAAGCGTATTTGCTATTACGGATACAGGATAATGGTAAAG
GTTTTAATGTAGATGATAAGGTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCACTCGAAATAGGCGCAACG
TTTCATATTGTTTCTTTACCTGATGCAGGTACAAGAATAGAAGTTAAGGCACCATTAAATAAGGAGGATTCATATGCCAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A2C6WKA0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.116	99.424	0.876