Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   MNU47_RS08670 Genome accession   NZ_CP093202
Coordinates   1854843..1855418 (-) Length   191 a.a.
NCBI ID   WP_001829272.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain TSM-31     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1844519..1854336 1854843..1855418 flank 507


Gene organization within MGE regions


Location: 1844519..1855418
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MNU47_RS08560 (MNU47_08555) - 1844519..1845076 (-) 558 WP_002458045.1 GNAT family N-acetyltransferase -
  MNU47_RS08565 (MNU47_08560) - 1845306..1845521 (+) 216 WP_001831694.1 NINE protein -
  MNU47_RS11950 - 1845625..1845741 (+) 117 WP_002486587.1 SAR1012 family small protein -
  MNU47_RS08570 (MNU47_08565) - 1846064..1846594 (+) 531 WP_002475755.1 GNAT family N-acetyltransferase -
  MNU47_RS11955 - 1846830..1847025 (+) 196 Protein_1659 hypothetical protein -
  MNU47_RS08575 (MNU47_08570) - 1847368..1847601 (-) 234 Protein_1660 AAA family ATPase -
  MNU47_RS08580 (MNU47_08575) - 1847980..1848207 (+) 228 WP_002505719.1 DUF2188 domain-containing protein -
  MNU47_RS08585 (MNU47_08580) - 1848204..1848407 (-) 204 WP_002505718.1 hypothetical protein -
  MNU47_RS08590 (MNU47_08585) - 1848422..1848634 (-) 213 Protein_1663 DUF771 domain-containing protein -
  MNU47_RS08595 (MNU47_08590) - 1848638..1849393 (-) 756 Protein_1664 phage antirepressor KilAC domain-containing protein -
  MNU47_RS08600 (MNU47_08595) - 1849443..1849649 (+) 207 WP_002439266.1 hypothetical protein -
  MNU47_RS08605 (MNU47_08600) - 1849638..1849802 (-) 165 WP_002439265.1 hypothetical protein -
  MNU47_RS08610 (MNU47_08605) - 1849799..1850053 (-) 255 WP_002505715.1 helix-turn-helix transcriptional regulator -
  MNU47_RS08615 (MNU47_08610) - 1850247..1850576 (+) 330 WP_002439260.1 helix-turn-helix domain-containing protein -
  MNU47_RS08620 (MNU47_08615) - 1850588..1851049 (+) 462 WP_002469232.1 ImmA/IrrE family metallo-endopeptidase -
  MNU47_RS08625 (MNU47_08620) - 1851065..1851583 (+) 519 WP_002505714.1 hypothetical protein -
  MNU47_RS08630 (MNU47_08625) - 1851585..1852028 (+) 444 WP_002439254.1 hypothetical protein -
  MNU47_RS08635 (MNU47_08630) - 1852101..1852295 (+) 195 WP_002439253.1 hypothetical protein -
  MNU47_RS08640 (MNU47_08635) - 1852364..1852879 (+) 516 WP_002439252.1 hypothetical protein -
  MNU47_RS08645 (MNU47_08640) - 1852881..1853216 (+) 336 WP_002439251.1 hypothetical protein -
  MNU47_RS08650 (MNU47_08645) - 1853272..1853670 (+) 399 Protein_1675 phage integrase SAM-like domain-containing protein -
  MNU47_RS08655 (MNU47_08650) - 1853776..1854336 (+) 561 WP_269770930.1 site-specific integrase -
  MNU47_RS08670 (MNU47_08665) comK/comK1 1854843..1855418 (-) 576 WP_001829272.1 competence protein ComK Regulator

Sequence

Protein


Download         Length: 191 a.a.        Molecular weight: 22782.87 Da        Isoelectric Point: 9.2887

>NTDB_id=662439 MNU47_RS08670 WP_001829272.1 1854843..1855418(-) (comK/comK1) [Staphylococcus epidermidis strain TSM-31]
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN

Nucleotide


Download         Length: 576 bp        

>NTDB_id=662439 MNU47_RS08670 WP_001829272.1 1854843..1855418(-) (comK/comK1) [Staphylococcus epidermidis strain TSM-31]
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
GACAAATGGTACTGAGATTATCAGATTTGATCAAACCCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAGTTTTATGGCAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATTTCTAGTAAACCACCT
ATTTTACTTACACCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCGGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCTTTAACACTCA
ATGTATCATTTCATAGTTTGTGGCATCAATACACCAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCCTCTTTAAATATTTTCGAGGCGCTTTCACGCTACTCTCT
TTTTGAAGAAAATTAG

Domains

Predicted by InterproScan.

ComK protein (ComK)

(7-158)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

76.757

96.859

0.743
  comK/comK1 Staphylococcus aureus N315

76.757

96.859

0.743