Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG609_RS36560 Genome accession   NZ_CP108529
Coordinates   8052464..8053129 (+) Length   221 a.a.
NCBI ID   WP_327276746.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_01224     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8047464..8058129
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG609_RS36540 (OG609_36610) - 8048554..8049768 (+) 1215 WP_327276742.1 geranylgeranyl reductase family protein -
  OG609_RS36545 (OG609_36615) - 8049823..8050275 (-) 453 WP_327276743.1 nitroreductase/quinone reductase family protein -
  OG609_RS36550 (OG609_36620) - 8050405..8051121 (+) 717 WP_327276744.1 TetR/AcrR family transcriptional regulator -
  OG609_RS36555 (OG609_36625) - 8051226..8052467 (+) 1242 WP_327276745.1 sensor histidine kinase -
  OG609_RS36560 (OG609_36630) vraR 8052464..8053129 (+) 666 WP_327276746.1 response regulator transcription factor Regulator
  OG609_RS36565 (OG609_36635) - 8053442..8053612 (+) 171 Protein_7219 MarR family transcriptional regulator -
  OG609_RS36570 (OG609_36640) - 8053646..8054401 (-) 756 WP_327276747.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OG609_RS36575 (OG609_36645) - 8054423..8054791 (-) 369 WP_327276748.1 hypothetical protein -
  OG609_RS36580 (OG609_36650) - 8054872..8056086 (-) 1215 WP_327276749.1 MFS transporter -
  OG609_RS36585 (OG609_36655) - 8056208..8057422 (+) 1215 WP_114243126.1 ROK family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23954.67 Da        Isoelectric Point: 4.7147

>NTDB_id=662352 OG609_RS36560 WP_327276746.1 8052464..8053129(+) (vraR) [Streptomyces sp. NBC_01224]
MIRVLLADDQLLVRAGFRALLDAQPDIEVAGEAADGEEAVRMVRELRPDTVLMDIRMPHLDGLAATRAITGDPELSDVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVGGDALLSPGVTRRLIAEFAARSKEPAAATGLSELTERER
EVMALVGIGLSNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=662352 OG609_RS36560 WP_327276746.1 8052464..8053129(+) (vraR) [Streptomyces sp. NBC_01224]
GTGATCCGCGTACTGCTCGCCGACGACCAGCTGCTGGTCCGGGCCGGTTTCCGGGCCCTGCTGGACGCTCAGCCCGACAT
CGAGGTGGCGGGGGAGGCCGCCGACGGTGAGGAGGCCGTACGCATGGTGCGCGAACTGCGGCCGGACACCGTGCTGATGG
ACATCCGGATGCCGCATCTCGATGGCCTGGCCGCGACCCGTGCCATCACCGGGGACCCTGAGCTGAGTGACGTCAAGGTG
GTCATGCTCACCACCTTCGAGCTCGACGAGTATGTCTTCGAGGCGATCCGCTCCGGTGCCTCCGGCTTTCTCGTCAAGGA
CACCGAACCGGAGGAACTGCTGCGGGCGGTACGTGCTGTGGTGGGCGGCGACGCACTGCTCTCACCGGGGGTCACCCGCC
GGCTGATCGCCGAGTTCGCGGCCCGGTCCAAGGAGCCCGCGGCGGCAACGGGGCTGAGCGAACTCACCGAACGGGAAAGG
GAGGTGATGGCACTCGTCGGCATAGGGCTCTCCAATGAGGAGATCGCCCGCCGGCTGGTCGTCAGCCCGCTCACCGCCAA
GACCCACGTCAGCCGCACCATGGTGAAGCTCGGTGCCCGCGACCGGGCTCAACTCGTTGTGCTCGCCTATGAGTCGGGGC
TCGTACGCCCCGGCTGGCTCGGTTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(154-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.14

97.285

0.371
  degU Bacillus subtilis subsp. subtilis str. 168

36.283

100

0.371