Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | MNU35_RS00330 | Genome accession | NZ_CP093170 |
| Coordinates | 74331..75680 (-) | Length | 449 a.a. |
| NCBI ID | WP_254106264.1 | Uniprot ID | - |
| Organism | Staphylococcus epidermidis strain TMDU-128 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 37294..75680 | 74331..75680 | within | 0 |
Gene organization within MGE regions
Location: 37294..75680
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MNU35_RS00155 (MNU35_00155) | mecA | 37294..39303 (-) | 2010 | WP_063852638.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| MNU35_RS00160 (MNU35_00160) | - | 39400..39507 (+) | 108 | Protein_29 | beta-lactam sensor/signal transducer MecR1 | - |
| MNU35_RS00165 (MNU35_00165) | - | 39548..40222 (+) | 675 | Protein_30 | IS6 family transposase | - |
| MNU35_RS00170 (MNU35_00170) | - | 40282..40710 (-) | 429 | WP_000671996.1 | VOC family protein | - |
| MNU35_RS00175 (MNU35_00175) | - | 40791..41720 (+) | 930 | WP_044466476.1 | HTH domain-containing protein | - |
| MNU35_RS00180 (MNU35_00180) | - | 41882..43894 (+) | 2013 | WP_162158236.1 | hypothetical protein | - |
| MNU35_RS00185 (MNU35_00185) | - | 44064..45173 (+) | 1110 | WP_049319120.1 | DNA polymerase | - |
| MNU35_RS00190 (MNU35_00190) | - | 45166..45537 (+) | 372 | WP_002437511.1 | hypothetical protein | - |
| MNU35_RS00195 (MNU35_00195) | - | 45534..47153 (+) | 1620 | WP_002437513.1 | DUF5906 domain-containing protein | - |
| MNU35_RS00200 (MNU35_00200) | - | 47380..49059 (+) | 1680 | WP_099774654.1 | recombinase family protein | - |
| MNU35_RS00205 (MNU35_00205) | - | 49148..49486 (+) | 339 | WP_017175172.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| MNU35_RS00210 (MNU35_00210) | - | 49580..49891 (+) | 312 | WP_001166716.1 | DUF960 family protein | - |
| MNU35_RS00215 (MNU35_00215) | - | 49907..50413 (+) | 507 | WP_000848380.1 | DUF1643 domain-containing protein | - |
| MNU35_RS00220 (MNU35_00220) | - | 50434..50880 (+) | 447 | WP_049389704.1 | RadC family protein | - |
| MNU35_RS00225 (MNU35_00225) | - | 51050..51922 (+) | 873 | WP_000373151.1 | HTH domain-containing protein | - |
| MNU35_RS00230 (MNU35_00230) | - | 51979..52269 (+) | 291 | WP_000065262.1 | hypothetical protein | - |
| MNU35_RS00235 (MNU35_00235) | - | 52285..52773 (+) | 489 | WP_000397419.1 | hypothetical protein | - |
| MNU35_RS00240 (MNU35_00240) | - | 52908..53435 (+) | 528 | WP_099774652.1 | hypothetical protein | - |
| MNU35_RS00245 (MNU35_00245) | - | 53497..53877 (+) | 381 | WP_254106258.1 | hypothetical protein | - |
| MNU35_RS00250 (MNU35_00250) | - | 53885..54106 (+) | 222 | WP_002504703.1 | hypothetical protein | - |
| MNU35_RS00255 (MNU35_00255) | - | 54260..54826 (+) | 567 | WP_099774648.1 | PepSY domain-containing protein | - |
| MNU35_RS00260 (MNU35_00260) | - | 54904..58023 (-) | 3120 | WP_099774646.1 | type I restriction endonuclease subunit R | - |
| MNU35_RS00265 (MNU35_00265) | - | 58007..59269 (-) | 1263 | WP_099774644.1 | restriction endonuclease subunit S | - |
| MNU35_RS00270 (MNU35_00270) | - | 59259..60773 (-) | 1515 | WP_145382875.1 | class I SAM-dependent DNA methyltransferase | - |
| MNU35_RS00275 (MNU35_00275) | - | 61202..61921 (+) | 720 | WP_032604338.1 | hypothetical protein | - |
| MNU35_RS00280 (MNU35_00280) | - | 61918..62814 (-) | 897 | WP_002437539.1 | hypothetical protein | - |
| MNU35_RS00285 (MNU35_00285) | - | 63113..66385 (-) | 3273 | WP_254106259.1 | N-6 DNA methylase | - |
| MNU35_RS00290 (MNU35_00290) | - | 66466..66873 (-) | 408 | WP_096638061.1 | hypothetical protein | - |
| MNU35_RS00295 (MNU35_00295) | - | 67126..67488 (-) | 363 | WP_254106260.1 | hypothetical protein | - |
| MNU35_RS12345 | - | 67533..67736 (-) | 204 | WP_367269962.1 | hypothetical protein | - |
| MNU35_RS00300 (MNU35_00300) | - | 67872..68375 (-) | 504 | WP_254106261.1 | DUF1643 domain-containing protein | - |
| MNU35_RS00305 (MNU35_00305) | - | 68390..68701 (-) | 312 | WP_070863099.1 | DUF960 domain-containing protein | - |
| MNU35_RS00310 (MNU35_00310) | - | 68794..69135 (-) | 342 | WP_145378659.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| MNU35_RS00315 (MNU35_00315) | - | 69744..70427 (-) | 684 | WP_145378657.1 | M15 family metallopeptidase | - |
| MNU35_RS00320 (MNU35_00320) | pbp4 | 70654..71898 (+) | 1245 | WP_254106262.1 | penicillin-binding protein PBP4 | - |
| MNU35_RS00325 (MNU35_00325) | ccrB | 72681..74309 (-) | 1629 | WP_254106263.1 | recombinase family protein | Machinery gene |
| MNU35_RS00330 (MNU35_00330) | ccrA | 74331..75680 (-) | 1350 | WP_254106264.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 52653.25 Da Isoelectric Point: 9.9639
>NTDB_id=662093 MNU35_RS00330 WP_254106264.1 74331..75680(-) (ccrA) [Staphylococcus epidermidis strain TMDU-128]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQVTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKTVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTPSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQVTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKTVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTPSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA
Nucleotide
Download Length: 1350 bp
>NTDB_id=662093 MNU35_RS00330 WP_254106264.1 74331..75680(-) (ccrA) [Staphylococcus epidermidis strain TMDU-128]
ATGAAACAAGTTATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAGTAACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGATTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGACTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGTCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACACCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCATATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA
ATGAAACAAGTTATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAGTAACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGATTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGACTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGTCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACACCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCATATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus N315 |
97.327 |
100 |
0.973 |
| ccrA | Staphylococcus aureus COL |
75.501 |
100 |
0.755 |