Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SRT_RS07865 Genome accession   NZ_AP014612
Coordinates   1628966..1630267 (-) Length   433 a.a.
NCBI ID   WP_128833685.1    Uniprot ID   A0A1L7LL78
Organism   Streptococcus troglodytae strain TKU 31     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1623966..1635267
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SRT_RS07840 (SRT_16120) - 1624011..1624658 (+) 648 WP_128833681.1 hypothetical protein -
  SRT_RS07845 (SRT_16130) - 1624735..1626438 (-) 1704 WP_128833682.1 zinc ribbon domain-containing protein -
  SRT_RS07850 (SRT_16140) - 1626458..1627552 (-) 1095 WP_128833683.1 hypothetical protein -
  SRT_RS07855 (SRT_16150) hpf 1627677..1628225 (-) 549 WP_002263024.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  SRT_RS07860 (SRT_16160) - 1628304..1628969 (-) 666 WP_128833684.1 ComF family protein -
  SRT_RS07865 (SRT_16170) comFA/cflA 1628966..1630267 (-) 1302 WP_128833685.1 DEAD/DEAH box helicase Machinery gene
  SRT_RS07870 (SRT_16180) - 1630340..1630969 (+) 630 WP_128833686.1 YigZ family protein -
  SRT_RS07875 (SRT_16190) cysK 1631060..1631984 (+) 925 Protein_1546 cysteine synthase A -
  SRT_RS07880 (SRT_16200) - 1632325..1633416 (-) 1092 WP_161940071.1 glycerol dehydrogenase -
  SRT_RS07885 (SRT_16210) - 1633454..1634122 (-) 669 WP_128833688.1 fructose-6-phosphate aldolase -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49405.53 Da        Isoelectric Point: 9.6701

>NTDB_id=66183 SRT_RS07865 WP_128833685.1 1628966..1630267(-) (comFA/cflA) [Streptococcus troglodytae strain TKU 31]
MENLENYYGRLLTENQMNSDLKKQAKTLPAMIKKPYYFICNRCGSQNNLDNTLPDGSIYCRACLVFGRLTSRDSLYYFEQ
KPFLKGQVLRWQGELTPFQKEVSDGLKKGVCHKENMLIHAVTGAGKTEMIYETLASILNQGGVVALASPRIDVCIELYKR
LSRDFSCPISLLHGESEAYERSPLVIATTHQLLKFYQAFDLLIIDEVDAFPFVDNKVLYYAVDHCLKSDGVKVFLTATST
DQLDKQVKQGRLKKLHLVRRFHANPLVIPQPIWLNLSLEKLQKGKLPRSFLQQITIQRQSQFPLLIFFPNIEDGLTFAKS
LQTYFPNEKIDFVSSLTIDRLEKVENFRKGKTQILVSTTILERGVTFPCVDVFVMVSNHYLFTKSSLVQIAGRVGRSADR
PDGKLLFFHNGMNRAMKKAIMEIKAMNKKGGFT

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=66183 SRT_RS07865 WP_128833685.1 1628966..1630267(-) (comFA/cflA) [Streptococcus troglodytae strain TKU 31]
ATGGAGAATTTAGAAAACTATTATGGTCGCCTCTTGACCGAAAATCAAATGAACAGCGATTTGAAAAAGCAAGCTAAAAC
TTTACCAGCTATGATAAAAAAGCCGTATTACTTTATCTGTAATCGTTGTGGCAGCCAGAACAATCTTGACAATACTCTAC
CGGATGGTTCTATCTATTGTCGAGCTTGTCTTGTTTTTGGACGTCTTACTAGTAGGGACAGCCTTTATTATTTTGAGCAA
AAGCCTTTTCTAAAGGGTCAGGTCTTAAGGTGGCAAGGGGAATTAACCCCTTTTCAGAAGGAAGTTTCTGATGGTCTAAA
GAAAGGTGTTTGCCATAAGGAAAATATGCTTATTCATGCCGTAACAGGTGCAGGCAAAACGGAGATGATTTATGAAACTC
TGGCTAGTATTCTCAATCAAGGAGGTGTGGTTGCACTTGCTAGTCCCCGCATTGATGTCTGCATCGAATTGTATAAACGT
TTAAGTCGTGACTTTTCTTGTCCTATCAGTCTTTTACATGGGGAATCAGAAGCTTATGAACGCAGTCCATTAGTGATTGC
AACCACACATCAACTTCTGAAATTTTACCAAGCTTTTGATTTGTTAATTATTGATGAAGTAGATGCCTTTCCCTTTGTTG
ACAATAAGGTGCTCTATTATGCTGTAGATCATTGTCTGAAATCAGATGGTGTCAAAGTATTTTTGACCGCAACTTCAACT
GACCAATTAGATAAACAGGTCAAACAAGGGCGACTTAAAAAACTGCACTTAGTCAGACGATTTCATGCCAATCCCTTAGT
TATTCCCCAGCCTATTTGGTTAAATTTATCTCTTGAAAAATTACAAAAAGGCAAATTACCACGCTCTTTTTTGCAGCAAA
TAACAATTCAAAGACAGAGTCAATTCCCTCTTCTAATCTTTTTTCCAAATATTGAAGATGGTTTAACCTTTGCTAAGTCA
CTGCAAACTTATTTTCCAAATGAGAAAATTGATTTTGTTTCCAGCTTGACAATAGATCGTTTAGAAAAAGTCGAAAATTT
TAGAAAAGGAAAAACACAAATTTTGGTTTCAACAACGATTTTGGAGAGAGGAGTAACCTTTCCTTGTGTAGATGTTTTTG
TCATGGTGAGTAATCACTATCTGTTTACCAAAAGTTCTCTGGTACAGATTGCTGGTCGTGTAGGTCGCTCTGCCGATAGA
CCAGATGGGAAATTACTTTTCTTTCATAATGGGATGAATAGAGCCATGAAAAAAGCTATTATGGAAATCAAGGCTATGAA
CAAAAAAGGAGGTTTTACATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(293-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1L7LL78

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae D39

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae R6

59.485

98.614

0.587
  comFA/cflA Streptococcus pneumoniae TIGR4

59.485

98.614

0.587
  comFA/cflA Streptococcus mitis NCTC 12261

58.782

98.614

0.58
  comFA/cflA Streptococcus mitis SK321

58.548

98.614

0.577
  comFA Lactococcus lactis subsp. cremoris KW2

52.03

90.993

0.473
  comFA Latilactobacillus sakei subsp. sakei 23K

38.679

97.921

0.379

Multiple sequence alignment