Detailed information NTG0661700

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: MMZ65_RS10630
• Genome accession: NZ_CP093032
• Coordinates: 2272749..2274974 (+)
• Length: 741 a.a.
• NCBI ID: WP_003138588.1
• Uniprot ID: A0A0H2ZCX3
• Organism: Pseudomonas aeruginosa strain H02
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2267749..2279974

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MMZ65_RS10605 (MMZ65_10610)	-	2268055..2268654 (-)	600	WP_016254241.1	PilZ domain-containing protein	-
MMZ65_RS10610 (MMZ65_10615)	-	2268757..2270007 (+)	1251	WP_003091170.1	lipoprotein-releasing ABC transporter permease subunit	-
MMZ65_RS10615 (MMZ65_10620)	lolD	2270000..2270683 (+)	684	WP_003109474.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
MMZ65_RS10620 (MMZ65_10625)	-	2270753..2271997 (+)	1245	WP_003105198.1	lipoprotein-releasing ABC transporter permease subunit	-
MMZ65_RS10625 (MMZ65_10630)	-	2272085..2272618 (-)	534	WP_003091165.1	DUF2062 domain-containing protein	-
MMZ65_RS10630 (MMZ65_10635)	comA	2272749..2274974 (+)	2226	WP_003138588.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
MMZ65_RS10635 (MMZ65_10640)	exbB	2275047..2275682 (+)	636	WP_003091163.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
MMZ65_RS10640 (MMZ65_10645)	-	2275679..2276119 (+)	441	WP_003091161.1	biopolymer transporter ExbD	-
MMZ65_RS10645 (MMZ65_10650)	lpxK	2276119..2277117 (+)	999	WP_003091159.1	tetraacyldisaccharide 4'-kinase	-
MMZ65_RS10650 (MMZ65_10655)	-	2277155..2277340 (+)	186	WP_003091157.1	Trm112 family protein	-
MMZ65_RS10655 (MMZ65_10660)	kdsB	2277340..2278104 (+)	765	WP_003130694.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
MMZ65_RS10660 (MMZ65_10665)	-	2278104..2278568 (+)	465	WP_003138590.1	low molecular weight protein-tyrosine-phosphatase	-
MMZ65_RS10665 (MMZ65_10670)	murB	2278565..2279584 (+)	1020	WP_003119807.1	UDP-N-acetylmuramate dehydrogenase	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 79970.55 Da
• Isoelectric Point: 10.4652

>NTDB_id=661700 MMZ65_RS10630 WP_003138588.1 2272749..2274974(+) (comA) [Pseudomonas aeruginosa strain H02]
MRLGLPALAAGLLALRFLAELPSVGWLLGMAAAGLLLLFGRLYWLGLFLLGFAWACGSAQVALDGRLAAELDGRTLWLEG
RVVDLPASGEGVTRFRLEEVSAARGVLLPERLRLSWRGAPPLMGGERWRLAVTLKRPRGLVNAAGFDYEAWLLAQRVGAV
GKVKAGQRLQPASGLDAWRDAWRQRLLAVDAQGRGAALAALVLGDGSGLSAAEWRMFQDTGTVHLMVISGSHISLLAGML
YGLVAALHRLGCWPRRLPWLPCACALGLLGAWSYGLMAGFEVPVRRACLMVSLALVWRLRFRHLGLLTPLLATLVLVLLV
EPLASLQAGFWLSFLAVALLLWLFAGRLGRWRWWAAWGRAQWGMALGLAMPLLALGLPLSLSGAPANLLAVPWIELLVVP
PALAGSLLLWVPGLGEGLLRAAGVSLDLLFRALGLLAGLAEAWQPPAAAAWSVALGMLGALCWLAPAGLPLRALGAALLL
PALLPSSPPVEWGRAEVRVLDVGQGLAVLVRTREHALLYDSGARQGAFDMGERVVVPVLRSLDLRRLDGLLLSHADNDHA
GGAPTVASRFPPGWLVSGEPARLPSPLFADSCDERSWSWDGVVFEQWAWAQAGDSNDRSCVLRVEADGEVLLLTGDISRA
AEHAWLARQADPRVDWLLAPHHGSRSSSGVAFVLRTRPRHVLVSRGWRNAFGHPHGEVMERYARVAAQVHDTARDGALTF
FLGSRGGARRERDSAHFWREK

Nucleotide

• Length: 2226 bp

>NTDB_id=661700 MMZ65_RS10630 WP_003138588.1 2272749..2274974(+) (comA) [Pseudomonas aeruginosa strain H02]
ATGCGCCTGGGATTGCCAGCCCTCGCCGCGGGGCTGCTGGCCCTGCGCTTCCTGGCGGAATTGCCGTCGGTCGGCTGGCT
GCTGGGCATGGCCGCCGCCGGACTGTTGCTGCTGTTCGGCCGGCTGTACTGGCTGGGGTTGTTCCTGCTCGGGTTCGCCT
GGGCCTGCGGCTCGGCGCAAGTCGCCCTGGACGGACGCCTGGCCGCCGAGCTGGATGGTCGCACCCTTTGGCTGGAGGGG
CGTGTGGTCGATCTGCCGGCGAGCGGCGAGGGCGTCACGCGCTTCCGGCTGGAGGAGGTCAGCGCTGCGCGGGGCGTGCT
TCTTCCCGAGCGTCTGCGCCTGAGCTGGCGCGGCGCGCCGCCGCTGATGGGCGGCGAACGCTGGCGCCTGGCGGTGACCC
TGAAACGCCCCCGCGGCCTGGTGAACGCGGCGGGTTTCGACTACGAGGCCTGGTTGTTGGCGCAGCGGGTCGGTGCTGTG
GGCAAGGTGAAGGCGGGCCAACGCCTGCAGCCGGCCAGCGGCCTGGATGCCTGGCGCGATGCCTGGCGCCAGCGCCTGCT
GGCGGTCGACGCACAGGGGCGCGGCGCCGCCCTGGCGGCGCTGGTGCTGGGGGATGGCTCGGGATTGAGCGCGGCCGAGT
GGCGAATGTTCCAGGACACCGGCACCGTGCATCTGATGGTCATCTCCGGTTCGCATATCTCGTTGCTGGCGGGGATGCTC
TATGGCCTGGTGGCGGCCTTGCATCGCCTGGGCTGCTGGCCGCGGCGCCTGCCCTGGCTGCCCTGTGCCTGCGCCCTGGG
TTTGCTTGGTGCCTGGAGCTACGGGTTGATGGCGGGTTTCGAGGTCCCGGTGCGGCGTGCTTGCCTGATGGTCAGCCTGG
CGCTGGTCTGGCGCCTGCGTTTCCGCCACCTGGGCTTGCTGACCCCGCTGCTGGCAACGCTGGTGCTGGTCTTGCTGGTC
GAGCCGCTGGCCAGCCTGCAGGCGGGGTTCTGGCTGTCGTTCCTGGCGGTTGCCCTGCTGCTCTGGCTGTTCGCCGGGCG
CCTTGGGCGCTGGCGCTGGTGGGCGGCCTGGGGGCGGGCGCAGTGGGGGATGGCGCTGGGGCTGGCGATGCCGCTGCTGG
CGCTGGGCCTGCCGTTGAGCCTGAGCGGAGCGCCGGCCAACCTGCTGGCGGTGCCTTGGATCGAACTGCTGGTAGTGCCC
CCGGCCCTGGCGGGGAGCCTGCTGCTATGGGTGCCCGGGCTGGGCGAGGGGCTGCTTCGCGCCGCTGGCGTTTCGCTGGA
CCTGCTGTTTCGTGCGCTTGGCCTGCTGGCGGGCCTGGCCGAGGCCTGGCAGCCACCCGCCGCAGCGGCCTGGAGCGTAG
CGCTGGGCATGCTCGGCGCGCTCTGCTGGCTGGCGCCGGCTGGCTTGCCGTTGCGTGCCCTCGGTGCCGCGTTGCTACTG
CCGGCGTTGTTGCCGTCATCGCCGCCTGTCGAATGGGGGCGGGCGGAAGTGCGGGTGCTGGACGTCGGCCAGGGGCTGGC
CGTGCTGGTGCGTACCCGGGAGCATGCCTTGCTCTATGACAGCGGTGCGCGGCAGGGGGCGTTCGACATGGGCGAGCGGG
TGGTGGTGCCGGTGCTGCGCAGCCTGGACCTGCGGCGCCTGGACGGCCTGTTGCTGAGCCATGCCGACAACGACCATGCA
GGCGGTGCTCCTACGGTCGCTTCCCGATTCCCGCCGGGTTGGCTGGTCAGCGGCGAACCCGCGCGCCTGCCTTCGCCGTT
GTTCGCGGACAGCTGCGACGAGCGGAGCTGGTCCTGGGATGGCGTGGTTTTCGAACAGTGGGCATGGGCGCAGGCCGGCG
ACAGCAACGACCGCTCCTGTGTGCTGAGGGTCGAGGCCGATGGCGAAGTCCTGCTGCTGACCGGGGACATCTCGCGTGCG
GCCGAGCATGCCTGGCTGGCGCGACAGGCCGATCCCCGGGTCGACTGGTTGCTGGCGCCGCATCATGGCAGCCGCAGTTC
CTCCGGAGTCGCCTTCGTGTTGCGTACGCGACCTCGCCATGTGCTGGTCTCGCGAGGTTGGCGCAACGCCTTCGGCCATC
CCCATGGCGAAGTGATGGAGCGTTACGCGAGGGTCGCCGCGCAGGTCCACGACACGGCACGCGACGGTGCCCTGACGTTT
TTCCTCGGAAGCCGTGGCGGCGCACGCCGGGAGCGTGATTCGGCGCACTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (501-666)

• Domain of unknown function (DUF4131) (DUF4131) (21-168)

• Competence protein (Competence) (201-464)

3D structure

• AlphaFold DB: A0A0H2ZCX3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	58.946	97.301	0.574
comA	Ralstonia pseudosolanacearum GMI1000	35.611	100	0.366