Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   SRT_RS01405 Genome accession   NZ_AP014612
Coordinates   270667..271998 (+) Length   443 a.a.
NCBI ID   WP_128832793.1    Uniprot ID   -
Organism   Streptococcus troglodytae strain TKU 31     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 265667..276998
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SRT_RS01380 (SRT_02600) dnaI 265833..266732 (+) 900 WP_128832788.1 primosomal protein DnaI -
  SRT_RS01385 (SRT_02610) der 266745..268055 (+) 1311 WP_128832789.1 ribosome biogenesis GTPase Der -
  SRT_RS01390 (SRT_02620) - 268135..268761 (+) 627 WP_128832790.1 ribonuclease P -
  SRT_RS01395 (SRT_02630) - 268808..269446 (+) 639 WP_128832791.1 VTT domain-containing protein -
  SRT_RS01400 (SRT_02640) comE/blpR 269918..270670 (+) 753 WP_128832792.1 response regulator transcription factor Regulator
  SRT_RS01405 (SRT_02650) comD/blpH 270667..271998 (+) 1332 WP_128832793.1 sensor histidine kinase Regulator
  SRT_RS01410 (SRT_02660) - 272140..272279 (-) 140 Protein_246 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SRT_RS01415 (SRT_02670) - 272546..272770 (+) 225 WP_128832794.1 Blp family class II bacteriocin -
  SRT_RS01425 (SRT_02680) - 273102..273506 (+) 405 WP_128832795.1 hypothetical protein -
  SRT_RS10540 (SRT_02690) - 273629..273840 (-) 212 Protein_249 IS3 family transposase -
  SRT_RS10390 - 274278..274442 (+) 165 WP_128832796.1 hypothetical protein -
  SRT_RS01440 (SRT_02700) - 274849..275061 (+) 213 WP_128832797.1 Blp family class II bacteriocin -
  SRT_RS01445 - 275224..275434 (+) 211 Protein_252 bacteriocin secretion protein -
  SRT_RS01450 (SRT_02710) - 275913..276941 (+) 1029 WP_128832798.1 thioredoxin family protein -

Sequence

Protein


Download         Length: 443 a.a.        Molecular weight: 50739.98 Da        Isoelectric Point: 9.8236

>NTDB_id=66161 SRT_RS01405 WP_128832793.1 270667..271998(+) (comD/blpH) [Streptococcus troglodytae strain TKU 31]
MNEALMILSNGLLTYLTVLFLLFLFSKVSNVTLSKKELTLFSISNFLIMIAVTMVNVNLFYPAEPLYFIVLSIYLNRQNS
LSLNIFYGLLPVASSDLFRRAIIFFILDGNQGIVMGSSIITTYMIEFAGIALSYLFLSVFNVDIGRLKDSLTKMKVKKRL
IPMNITMLLYYLLIQALYVIESYNVIPTLKFCKFVVIVYLILFLILISFLSQYTKQKVQNEIMAQKEAQIRNITQYSQQI
ESLYKDIRSFRHDYLNILTSLRLGIENKDLASIEKIYHQVLEKTRPQLQDTRYNIGHLANIQNDAVKGILSAKILEAQNK
KIAVNVEVSSQIQLPEMELQLLDFITILSILCDNAIEAALESPKPKVQLAFFKKNGNIVFIIQNSTKEKQIDVSNIFKEN
YSTKGSNRGIGLAKVNHILEHYPKTSLQTSSHHHLFKQILIMK

Nucleotide


Download         Length: 1332 bp        

>NTDB_id=66161 SRT_RS01405 WP_128832793.1 270667..271998(+) (comD/blpH) [Streptococcus troglodytae strain TKU 31]
ATGAATGAAGCCTTAATGATACTTTCAAATGGTTTATTAACTTATCTAACCGTTCTATTTCTCTTGTTTCTATTTTCTAA
GGTAAGTAATGTCACTTTATCGAAAAAGGAATTAACTCTTTTTTCGATAAGCAATTTTCTGATAATGATTGCTGTTACGA
TGGTAAATGTAAACCTGTTTTATCCTGCAGAGCCTCTTTATTTTATAGTTTTATCAATTTATCTTAATAGACAGAATAGT
CTTTCTCTAAATATATTTTATGGTCTGCTGCCTGTTGCCAGTTCTGACTTGTTTAGACGGGCAATCATATTCTTTATCTT
GGATGGAAATCAAGGAATTGTAATGGGCAGTAGCATTATAACCACCTATATGATCGAGTTTGCAGGAATAGCGCTAAGTT
ACCTCTTTCTAAGTGTGTTCAATGTTGATATTGGTCGACTTAAAGATAGTTTGACCAAGATGAAGGTCAAAAAACGCTTG
ATCCCAATGAATATTACTATGCTTCTATACTACCTTTTAATACAGGCATTGTATGTTATAGAGAGTTATAATGTGATACC
GACTTTAAAATTTTGTAAATTTGTCGTTATTGTCTATCTTATTTTATTTTTGATTCTGATCTCATTTTTAAGCCAATATA
CCAAACAAAAGGTTCAAAATGAGATAATGGCACAAAAGGAAGCTCAGATTCGAAATATCACCCAGTATAGTCAGCAGATA
GAATCTCTTTACAAGGATATTCGAAGTTTCCGCCATGATTATCTGAATATTTTAACTAGCCTCAGATTAGGCATTGAAAA
TAAAGATTTAGCTAGTATTGAAAAGATTTACCATCAGGTTTTAGAAAAAACAAGACCTCAATTGCAGGATACCCGTTATA
ATATCGGCCATCTAGCTAATATCCAAAACGATGCTGTCAAGGGTATCTTGTCAGCAAAAATCTTAGAAGCTCAGAATAAA
AAAATTGCTGTCAATGTAGAAGTCTCAAGTCAAATACAGCTGCCTGAGATGGAGTTGCAGTTGCTTGATTTCATTACCAT
ACTTTCTATCTTGTGCGATAATGCTATTGAGGCCGCTCTCGAATCACCAAAACCTAAAGTTCAGTTAGCCTTTTTTAAGA
AAAATGGCAACATAGTCTTTATCATTCAGAATTCCACCAAAGAAAAACAAATAGATGTGAGTAACATTTTTAAAGAAAAC
TATTCCACTAAGGGCTCCAATCGCGGTATTGGTTTAGCAAAGGTGAATCATATTCTTGAACATTATCCCAAAACCAGTTT
ACAAACAAGCAGTCATCATCATTTATTCAAGCAAATCCTAATAATGAAATAG

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(342-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

95.485

100

0.955

Multiple sequence alignment