Detailed information    

insolico Bioinformatically predicted

Overview

Name   comS   Type   Regulator
Locus tag   M3B_RS10135 Genome accession   NZ_AP014596
Coordinates   48470..48568 (+) Length   32 a.a.
NCBI ID   WP_020833188.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M3-b     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 43470..53568
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M3B_RS00250 (M3B_0051) - 44336..45676 (+) 1341 WP_002986685.1 hypothetical protein -
  M3B_RS00255 (M3B_0053) purB 46045..47337 (+) 1293 WP_011054098.1 adenylosuccinate lyase -
  M3B_RS00260 (M3B_0054) comR 47468..48379 (+) 912 WP_011054099.1 helix-turn-helix domain-containing protein Regulator
  M3B_RS10135 comS 48470..48568 (+) 99 WP_020833188.1 quorum-sensing system DWW-type pheromone Regulator
  M3B_RS00265 (M3B_0055) ruvB 48599..49597 (+) 999 WP_011054100.1 Holliday junction branch migration DNA helicase RuvB -
  M3B_RS00270 (M3B_0056) - 49735..50172 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  M3B_RS00275 - 50195..50596 (+) 402 WP_011017240.1 MORN repeat-containing protein -
  M3B_RS00280 (M3B_0058) - 50593..52368 (+) 1776 WP_011054101.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 32 a.a.        Molecular weight: 3758.63 Da        Isoelectric Point: 10.7919

>NTDB_id=66129 M3B_RS10135 WP_020833188.1 48470..48568(+) (comS) [Streptococcus pyogenes strain M3-b]
MLKKVKPFLLLAAVVAFKVARVMHEFDWWNLG

Nucleotide


Download         Length: 99 bp        

>NTDB_id=66129 M3B_RS10135 WP_020833188.1 48470..48568(+) (comS) [Streptococcus pyogenes strain M3-b]
ATGTTAAAAAAAGTTAAGCCATTTTTACTATTAGCCGCAGTAGTTGCATTTAAAGTTGCTCGTGTAATGCATGAATTTGA
TTGGTGGAATCTTGGTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS315

100

100

1
  comS Streptococcus pyogenes MGAS8232

45.161

96.875

0.437

Multiple sequence alignment