Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   ML603_RS07280 Genome accession   NZ_CP092887
Coordinates   1475272..1476597 (-) Length   441 a.a.
NCBI ID   WP_241066980.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain Karl     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1470272..1481597
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ML603_RS07270 (ML603_07270) raiA 1474007..1474555 (-) 549 WP_003061817.1 ribosome-associated translation inhibitor RaiA -
  ML603_RS09920 - 1474635..1475300 (-) 666 WP_143927828.1 ComF family protein -
  ML603_RS07280 (ML603_07280) comFA/cflA 1475272..1476597 (-) 1326 WP_241066980.1 DEAD/DEAH box helicase Machinery gene
  ML603_RS07285 (ML603_07285) - 1476653..1477291 (+) 639 WP_003062333.1 YigZ family protein -
  ML603_RS07290 (ML603_07290) cysK 1477395..1478330 (+) 936 WP_138126234.1 cysteine synthase A -
  ML603_RS07295 (ML603_07295) - 1478482..1478841 (-) 360 WP_111717284.1 S1 RNA-binding domain-containing protein -
  ML603_RS07300 (ML603_07300) - 1478841..1480241 (-) 1401 WP_138126238.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ML603_RS07305 (ML603_07305) - 1480278..1480919 (-) 642 WP_014612503.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49344.49 Da        Isoelectric Point: 9.7069

>NTDB_id=660939 ML603_RS07280 WP_241066980.1 1475272..1476597(-) (comFA/cflA) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
MEGIENSYGRLFLKHQLPKEVNHLAKTLESIVIIKGKVTCQRCHYQITAEARLPSGTYYCRFCLVFGRNQADRPLYYIPQ
HPFPIANYLQWKGILTPYQESISNQLVKNVHAKKPTLVHAVTGAGKTEMIYGAIAAVVNAGGWVCLASPRVDVCIELANR
LKAAFSCRVTLLHADSEAYQRSPIIVATTHQLLTFYKAFDLLIIDEVDAFPFVNNHQLQYAAQQAAKEGASSIVLTATST
KELEEQVKSGELEKLTLARRFHDNPLILPKFIRSFGLLKKIHCQKLPRALIKSISQQRKTGCPLLIFLPIIAMAELVTEL
LKLAFPEEQIACVSSQSADRVKDIDAFRQGKKGILVTTTILERGVTFPGVDVFVLMAQHRGYSSQSLVQIAGRVGRSIER
PTGKVYFFHDGISQAMRNARKEIKEMNQKGYSNDMPPMSTI

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=660939 ML603_RS07280 WP_241066980.1 1475272..1476597(-) (comFA/cflA) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
ATGGAAGGTATTGAAAATAGTTACGGTCGTTTATTTTTAAAACATCAATTGCCAAAAGAAGTAAATCATCTGGCAAAGAC
CTTGGAAAGTATAGTAATCATAAAAGGTAAAGTCACTTGTCAACGCTGTCATTATCAGATAACCGCAGAAGCGAGATTAC
CAAGCGGCACTTACTACTGTCGCTTCTGTCTCGTTTTTGGCCGAAATCAAGCTGATAGGCCTCTTTATTATATACCTCAA
CATCCTTTTCCTATAGCCAATTATCTTCAATGGAAGGGGATATTAACGCCCTACCAAGAAAGTATTTCAAACCAATTAGT
CAAGAATGTTCATGCTAAAAAACCTACTTTAGTGCATGCTGTTACCGGAGCCGGAAAGACAGAGATGATTTATGGTGCCA
TAGCAGCAGTTGTTAATGCTGGAGGTTGGGTTTGTTTAGCCAGCCCAAGGGTCGATGTTTGTATAGAACTTGCTAATCGC
TTAAAAGCTGCTTTTTCTTGCCGGGTTACTCTTTTACATGCTGACTCAGAAGCTTATCAAAGAAGTCCTATTATAGTAGC
TACTACCCATCAATTACTGACCTTTTATAAGGCTTTTGATCTTTTAATCATTGATGAAGTTGATGCTTTTCCTTTTGTCA
ATAATCATCAACTACAATATGCAGCGCAGCAAGCCGCTAAAGAAGGCGCTAGTAGTATCGTATTGACCGCGACATCGACC
AAAGAACTGGAAGAGCAGGTCAAAAGTGGGGAACTAGAGAAGCTGACATTAGCTAGACGATTCCATGATAATCCTTTGAT
TCTTCCGAAATTTATCAGGAGTTTTGGCCTATTAAAAAAAATTCACTGTCAAAAACTTCCTCGAGCTCTTATTAAATCTA
TCAGTCAGCAAAGGAAAACAGGATGTCCACTGCTAATTTTTCTTCCTATTATTGCCATGGCAGAATTAGTTACTGAATTA
TTAAAGTTAGCTTTTCCAGAGGAGCAAATTGCCTGTGTCTCTAGCCAATCAGCTGACAGAGTTAAAGACATTGATGCCTT
TCGTCAAGGAAAGAAAGGCATTTTGGTGACCACTACAATATTGGAAAGGGGTGTTACTTTCCCAGGCGTGGATGTCTTTG
TGCTAATGGCACAGCATAGAGGATACAGTTCTCAAAGCTTGGTTCAAATCGCAGGTCGTGTGGGGAGATCTATCGAAAGG
CCAACAGGGAAGGTGTATTTCTTTCACGATGGGATTAGTCAAGCAATGCGCAATGCAAGAAAAGAAATTAAAGAAATGAA
TCAGAAAGGTTATTCGAATGATATGCCTCCTATGTCAACGATTTAG

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(288-396)

DEAD/DEAH box helicase (DEAD)

(99-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

53.555

95.692

0.512
  comFA/cflA Streptococcus pneumoniae D39

53.555

95.692

0.512
  comFA/cflA Streptococcus pneumoniae R6

53.555

95.692

0.512
  comFA/cflA Streptococcus pneumoniae TIGR4

53.555

95.692

0.512
  comFA/cflA Streptococcus mitis NCTC 12261

52.093

97.506

0.508
  comFA/cflA Streptococcus mitis SK321

52.235

96.372

0.503
  comFA Lactococcus lactis subsp. cremoris KW2

45.854

92.971

0.426
  comFA Latilactobacillus sakei subsp. sakei 23K

37.587

97.732

0.367