Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | M3B_RS00625 | Genome accession | NZ_AP014596 |
| Coordinates | 99951..100904 (+) | Length | 317 a.a. |
| NCBI ID | WP_011054117.1 | Uniprot ID | A0A5S4TQH7 |
| Organism | Streptococcus pyogenes strain M3-b | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
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Genomic Context
Location: 94951..105904
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M3B_RS00585 (M3B_0117) | - | 95778..96143 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| M3B_RS00590 (M3B_0118) | comYA | 96236..97174 (+) | 939 | WP_011054114.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| M3B_RS00595 (M3B_0119) | comYB | 97110..98144 (+) | 1035 | WP_011054115.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| M3B_RS00600 (M3B_0120) | comYC | 98146..98472 (+) | 327 | WP_002986552.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| M3B_RS00605 (M3B_0121) | comGD | 98447..98875 (+) | 429 | WP_002986548.1 | competence type IV pilus minor pilin ComGD | - |
| M3B_RS00610 | comGE | 98832..99116 (+) | 285 | WP_002987779.1 | competence type IV pilus minor pilin ComGE | - |
| M3B_RS00615 (M3B_0123) | comYF | 99109..99543 (+) | 435 | WP_002992738.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| M3B_RS00620 (M3B_0124) | comGG | 99527..99853 (+) | 327 | WP_010921801.1 | competence type IV pilus minor pilin ComGG | - |
| M3B_RS00625 (M3B_0125) | comYH | 99951..100904 (+) | 954 | WP_011054117.1 | class I SAM-dependent methyltransferase | Machinery gene |
| M3B_RS00630 (M3B_0126) | - | 100963..102159 (+) | 1197 | WP_010921803.1 | acetate kinase | - |
| M3B_RS00635 (M3B_0127) | - | 102345..102653 (+) | 309 | WP_011054118.1 | hypothetical protein | - |
| M3B_RS00640 (M3B_0128) | proC | 102736..103506 (-) | 771 | WP_002992745.1 | pyrroline-5-carboxylate reductase | - |
| M3B_RS00645 (M3B_0129) | pepA | 103554..104621 (-) | 1068 | WP_011054119.1 | glutamyl aminopeptidase | - |
| M3B_RS00655 (M3B_0130) | - | 105086..105370 (+) | 285 | WP_002992749.1 | DUF4651 domain-containing protein | - |
| M3B_RS00660 (M3B_0131) | - | 105367..105684 (+) | 318 | WP_002992751.1 | thioredoxin family protein | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 36027.22 Da Isoelectric Point: 4.7205
>NTDB_id=66079 M3B_RS00625 WP_011054117.1 99951..100904(+) (comYH) [Streptococcus pyogenes strain M3-b]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALIMLPDSIFGHPSNAKSIIVLQKQIDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALIMLPDSIFGHPSNAKSIIVLQKQIDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
Nucleotide
Download Length: 954 bp
>NTDB_id=66079 M3B_RS00625 WP_011054117.1 99951..100904(+) (comYH) [Streptococcus pyogenes strain M3-b]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGATACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCACTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTATGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAATAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGATACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCACTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTATGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAATAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
66.139 |
99.685 |
0.659 |
| comYH | Streptococcus mutans UA140 |
65.823 |
99.685 |
0.656 |