Detailed information NTG0660760

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG295_RS19475
• Genome accession: NZ_CP108442
• Coordinates: 4352537..4353661 (-)
• Length: 374 a.a.
• NCBI ID: WP_030236804.1
• Uniprot ID: A0A2K8PHY8
• Organism: Streptomyces sp. NBC_01276
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4347537..4358661

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG295_RS19445 (OG295_19455)	cseB	4347605..4348318 (-)	714	WP_371678010.1	two-component system response regulator CseB	-
OG295_RS19450 (OG295_19460)	-	4348335..4348985 (-)	651	WP_371678011.1	hypothetical protein	-
OG295_RS19455 (OG295_19465)	-	4349024..4349584 (-)	561	WP_030236813.1	SigE family RNA polymerase sigma factor	-
OG295_RS19460 (OG295_19470)	-	4349812..4350732 (-)	921	WP_371678012.1	A/G-specific adenine glycosylase	-
OG295_RS19465 (OG295_19475)	-	4350761..4351369 (-)	609	WP_371678013.1	phosphatase PAP2 family protein	-
OG295_RS19470 (OG295_19480)	-	4351593..4352330 (+)	738	WP_371678014.1	hypothetical protein	-
OG295_RS19475 (OG295_19485)	disA	4352537..4353661 (-)	1125	WP_030236804.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG295_RS19480 (OG295_19490)	radA/sms	4353861..4355279 (-)	1419	WP_266839796.1	DNA repair protein RadA	Machinery gene
OG295_RS19485 (OG295_19495)	-	4355427..4357205 (+)	1779	WP_371678015.1	hypothetical protein	-
OG295_RS19490 (OG295_19500)	-	4357211..4358029 (-)	819	WP_371678016.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40364.36 Da
• Isoelectric Point: 5.1189

>NTDB_id=660760 OG295_RS19475 WP_030236804.1 4352537..4353661(-) (disA) [Streptomyces sp. NBC_01276]
MAAKDGASAPGKSGASSKHDALMRASLSAVAPGQPLRDGLERIVRGNTGGLIVLGMDKNVEAMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCGFPVVSVSQSMRLIALYVDGERRVLEESGA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELTV
GIEQERELVIRDYVPEPTAKRSRTVEEALPALDALTHPELLELAIVAKALGYTGSPETLDSAVSPRGYRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=660760 OG295_RS19475 WP_030236804.1 4352537..4353661(-) (disA) [Streptomyces sp. NBC_01276]
GTGGCAGCCAAGGACGGGGCATCAGCACCCGGGAAGTCCGGCGCGAGCTCCAAGCACGACGCGCTGATGCGCGCCTCGCT
GAGCGCCGTCGCGCCTGGTCAGCCCCTGCGCGACGGCCTGGAGCGGATCGTCCGCGGCAACACGGGCGGGCTCATCGTCC
TCGGCATGGACAAGAACGTCGAGGCGATGTGCACGGGCGGCTTCGTCCTGGACGTGGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGCGCTCATCCTCGACAAGGACATCACCAAGATCCTGCGGGCCGGCGTGCAGCTGGTGCC
CGACGCGTCGATCCCGACGGAGGAGACCGGCACCCGGCACCGCACCGCGGACCGCGTCTCGAAGCAGTGCGGCTTCCCGG
TGGTCTCCGTGTCCCAGTCGATGCGGCTGATCGCCCTCTACGTCGACGGGGAGCGGCGGGTCCTGGAGGAGTCCGGGGCG
ATCCTGTCGCGGGCGAACCAGGCGCTGGCCACCCTGGAGCGGTACAAGCTGCGGCTCGACGAGGTCGCGGGGACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTCACCGTCCGCGACGTGACGGCGGTCGCCCAGCGGCTGGAAATGGTCCGCCGGATCG
CGACGGAAATCGCCGAGTACGTGGTCGAACTGGGCACGGACGGACGACTGCTGTCGCTCCAGCTGGACGAACTGACCGTC
GGCATCGAGCAGGAGCGGGAGCTGGTGATCCGGGACTACGTTCCGGAGCCGACGGCGAAGCGTTCCCGCACGGTGGAGGA
AGCGCTGCCGGCGCTGGACGCGCTGACCCATCCGGAACTGCTGGAACTGGCGATCGTGGCGAAGGCCCTGGGGTACACCG
GCTCGCCGGAGACCCTCGACTCGGCGGTGTCGCCGCGCGGGTACCGGCTGCTGGCCAAGGTGCCGAGGCTGCCGGGGGCG
ATCATCGAGCGGCTGGTCGAGCACTTCGGCGGGCTGCAGAAGCTGCTGGCGGCGTCGGTGGACGACCTCCAGACGGTGGA
CGGCGTCGGCGAGGCCCGTGCGCGCAGCGTCCGCGAGGGCCTGTCCCGCCTGGCGGAGTCGTCGATCCTGGAACGCTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

3D structure

• AlphaFold DB: A0A2K8PHY8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.983	96.524	0.444