Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   MK848_RS19645 Genome accession   NZ_CP092824
Coordinates   3827593..3828249 (+) Length   218 a.a.
NCBI ID   WP_003232942.1    Uniprot ID   A0AAQ3ENL6
Organism   Bacillus subtilis strain S1     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3822593..3833249
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MK848_RS19615 (MK848_19575) oppF 3823060..3823977 (+) 918 WP_003239287.1 oligopeptide ABC transporter ATP-binding protein OppF -
  MK848_RS19620 (MK848_19580) yjbB 3824083..3825300 (+) 1218 WP_101172486.1 MFS transporter -
  MK848_RS19625 (MK848_19585) yjbC 3825464..3826042 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  MK848_RS19630 (MK848_19590) spx 3826223..3826618 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  MK848_RS19635 (MK848_19595) yjbE 3826661..3827317 (-) 657 WP_003232944.1 TerC family protein -
  MK848_RS19640 (MK848_19600) - 3827486..3827626 (+) 141 WP_119122854.1 hypothetical protein -
  MK848_RS19645 (MK848_19605) mecA 3827593..3828249 (+) 657 WP_003232942.1 adaptor protein MecA Regulator
  MK848_RS19650 (MK848_19610) - 3828244..3828366 (-) 123 WP_128473814.1 hypothetical protein -
  MK848_RS19655 (MK848_19615) coiA 3828410..3829561 (+) 1152 WP_029317613.1 competence protein CoiA Machinery gene
  MK848_RS19660 (MK848_19620) pepF 3829791..3831620 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  MK848_RS19665 (MK848_19625) - 3831658..3831825 (-) 168 WP_003244944.1 hypothetical protein -
  MK848_RS19670 (MK848_19630) spxH 3832139..3833038 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25762.62 Da        Isoelectric Point: 4.0841

>NTDB_id=660471 MK848_RS19645 WP_003232942.1 3827593..3828249(+) (mecA) [Bacillus subtilis strain S1]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSNLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=660471 MK848_RS19645 WP_003232942.1 3827593..3828249(+) (mecA) [Bacillus subtilis strain S1]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAGATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAATTTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991