Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   MK848_RS08430 Genome accession   NZ_CP092824
Coordinates   1638263..1638907 (-) Length   214 a.a.
NCBI ID   WP_003220716.1    Uniprot ID   -
Organism   Bacillus subtilis strain S1     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 1633263..1643907
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MK848_RS08395 (MK848_08390) mrpB 1634453..1634884 (+) 432 WP_003228819.1 Na(+)/H(+) antiporter subunit B -
  MK848_RS08400 (MK848_08395) mrpC 1634884..1635225 (+) 342 WP_003220730.1 Na(+)/H(+) antiporter subunit C -
  MK848_RS08405 (MK848_08400) mrpD 1635218..1636699 (+) 1482 WP_241495649.1 Na+/H+ antiporter subunit D -
  MK848_RS08410 (MK848_08405) mrpE 1636705..1637181 (+) 477 WP_003228815.1 Na+/H+ antiporter subunit E -
  MK848_RS08415 (MK848_08410) mrpF 1637181..1637465 (+) 285 WP_003228814.1 Na(+)/H(+) antiporter subunit F1 -
  MK848_RS08420 (MK848_08415) mnhG 1637449..1637823 (+) 375 WP_014477830.1 monovalent cation/H(+) antiporter subunit G -
  MK848_RS08425 (MK848_08420) yuxO 1637864..1638244 (-) 381 WP_017695528.1 hotdog fold thioesterase -
  MK848_RS08430 (MK848_08425) comA 1638263..1638907 (-) 645 WP_003220716.1 two-component system response regulator ComA Regulator
  MK848_RS08435 (MK848_08430) comP 1638988..1641300 (-) 2313 WP_047183111.1 histidine kinase Regulator
  MK848_RS08440 (MK848_08435) comX 1641316..1641537 (-) 222 WP_014114983.1 competence pheromone ComX -
  MK848_RS08445 (MK848_08440) - 1641534..1642403 (-) 870 WP_161476745.1 polyprenyl synthetase family protein -
  MK848_RS08450 (MK848_08445) degQ 1642588..1642728 (-) 141 WP_003220708.1 degradation enzyme regulation protein DegQ Regulator
  MK848_RS08455 (MK848_08450) - 1642950..1643075 (+) 126 WP_003228793.1 hypothetical protein -
  MK848_RS08460 (MK848_08455) - 1643189..1643557 (+) 369 WP_003243784.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24128.51 Da        Isoelectric Point: 4.6857

>NTDB_id=660429 MK848_RS08430 WP_003220716.1 1638263..1638907(-) (comA) [Bacillus subtilis strain S1]
MKKILVIDDHPAVMEGTKTILETDSNLSVDCLSPEPSEQFIKQHDFSSYDLILMDLNLGGEVNGMELSKQILQENPHCKI
IVYTGYEVEDYFEEAIRAGLHGAISKTESKEKITQYIYHVLNGEILVDFAYFKQLMTQQKTKPAPSSQKEQDVLTPRECL
ILQEVEKGFTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDGVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=660429 MK848_RS08430 WP_003220716.1 1638263..1638907(-) (comA) [Bacillus subtilis strain S1]
ATGAAAAAGATACTAGTGATTGATGACCATCCGGCTGTCATGGAAGGCACCAAGACAATTTTGGAAACGGATTCGAATTT
GTCTGTTGATTGTCTCAGTCCTGAACCGAGCGAACAGTTTATCAAGCAGCATGATTTCTCGTCATATGATCTCATTTTAA
TGGATCTGAATTTAGGCGGCGAGGTCAATGGGATGGAGCTTTCTAAACAGATTTTACAAGAGAATCCTCATTGTAAAATT
ATCGTGTATACCGGTTATGAGGTCGAGGATTATTTCGAGGAAGCGATTCGTGCGGGTCTGCACGGTGCCATCAGCAAAAC
GGAATCTAAAGAAAAGATCACCCAATACATATACCACGTACTCAACGGAGAAATTTTAGTCGATTTTGCTTACTTTAAAC
AGCTGATGACTCAGCAAAAAACAAAGCCGGCTCCTTCCTCTCAAAAAGAACAAGATGTGCTCACACCTAGAGAATGCCTG
ATTCTTCAAGAAGTTGAAAAGGGATTTACAAACCAAGAAATCGCAGATGCCCTTCATTTAAGCAAGCGGTCCATTGAATA
CAGCTTGACATCGATTTTCAATAAGCTGAATGTCGGTTCACGGACGGAAGCGGTTTTGATTGCGAAATCAGACGGTGTAC
TTTAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-208)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

100

100

1