Detailed information NTG0660146

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG622_RS21255
• Genome accession: NZ_CP108394
• Coordinates: 4857141..4858265 (+)
• Length: 374 a.a.
• NCBI ID: WP_371578134.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_01314
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4852141..4863265

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG622_RS21245 (OG622_21305)	-	4853989..4855374 (+)	1386	WP_371578131.1	alpha/beta hydrolase	-
OG622_RS21250 (OG622_21310)	radA/sms	4855650..4857059 (+)	1410	WP_371578132.1	DNA repair protein RadA	Machinery gene
OG622_RS21255 (OG622_21315)	disA	4857141..4858265 (+)	1125	WP_371578134.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG622_RS21260 (OG622_21320)	-	4858369..4859208 (-)	840	WP_371578136.1	hypothetical protein	-
OG622_RS21265 (OG622_21325)	-	4859510..4860580 (+)	1071	WP_371578138.1	LLM class flavin-dependent oxidoreductase	-
OG622_RS21270 (OG622_21330)	-	4860664..4861581 (+)	918	WP_371578140.1	A/G-specific adenine glycosylase	-
OG622_RS21275 (OG622_21335)	-	4861912..4862463 (+)	552	WP_371578142.1	SigE family RNA polymerase sigma factor	-
OG622_RS21280 (OG622_21340)	-	4862451..4863125 (+)	675	WP_371578144.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40165.03 Da
• Isoelectric Point: 5.1026

>NTDB_id=660146 OG622_RS21255 WP_371578134.1 4857141..4858265(+) (disA) [Streptomyces sp. NBC_01314]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGFDKTVEPMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSTDLSKILRAGVQLVPDPMIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLVALYVDGHRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALRELDALAHAELLELPTVARALGYTGSPEGMDSAVSPRGYRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=660146 OG622_RS21255 WP_371578134.1 4857141..4858265(+) (disA) [Streptomyces sp. NBC_01314]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGCGGGAGCTCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCCGTGGCCCCAGGCACGGCCCTGCGCGACGGGCTTGAGCGGATTCTCCGCGGCAACACGGGCGGGCTCATCGTGC
TCGGCTTCGACAAGACCGTCGAGCCGATGTGCACCGGTGGATTCGTCCTGGATGTCGAGTTCACGGCCACGCGTCTGCGT
GAGCTGTGCAAGCTCGACGGCGGAATCGTCCTGTCCACGGACCTCTCCAAGATCCTCCGGGCGGGCGTCCAACTGGTCCC
CGACCCGATGATCCCCACCGAGGAGACGGGCACCCGGCACCGCACGGCCGACCGCGTGAGCAAGCAGGTCGGGTTCCCGG
TCGTCTCGGTCTCCCAGTCGATGCGCCTGGTCGCGCTGTACGTCGACGGCCACCGGCGCGTACTGGAGGACTCGGCGGCG
ATCCTGTCCCGCGCGAACCAGGCCCTGGCGACCCTGGAGCGGTACAAGCTCCGCCTGGACGAGGTGGCGGGCACCCTGTC
CGCACTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTGTCGGCGGTCGCCCAGCGACTGGAGATGGTCCGCCGCATCG
CCACCGAAATCGCCGAATACGTGGTCGAACTGGGCACGGACGGCCGCCTTCTGGCCCTCCAGCTCGACGAGCTGATCGCG
GGCGTCGAACCGGAACGCGAGCTGGTCGTCCGCGACTACGTCCCGGAACCCACCGCCAAACGCTCCCGCACGGTCGACGA
GGCCCTCCGCGAGCTCGACGCCCTCGCCCACGCCGAGCTCCTCGAACTCCCCACGGTCGCCCGCGCCCTCGGCTACACCG
GCTCCCCCGAGGGCATGGACTCCGCGGTCTCCCCGCGCGGCTACCGCCTCCTGGCCAAGGTCCCCCGCCTCCCGGGCGCC
ATCATCGACCGGCTCGTCGAACACTTCGGCGGTCTCCAGAAACTCCTCGCCGCCAGCGTCGACGACCTGCAGACGGTCGA
CGGAGTGGGCGAGGCCCGCGCCCGCAGCGTCCGCGAGGGCCTGTCGCGCCTGGCGGAGTCGTCGATCCTGGAGCGTTACG
TCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-295)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	44.875	96.524	0.433