Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   MK801_RS04225 Genome accession   NZ_CP092748
Coordinates   798956..800431 (+) Length   491 a.a.
NCBI ID   WP_254255784.1    Uniprot ID   -
Organism   Lactococcus lactis strain 17M1     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 793956..805431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MK801_RS04185 (MK801_04185) - 794042..794407 (+) 366 WP_254255780.1 metallophosphoesterase -
  MK801_RS04190 (MK801_04190) - 794447..794878 (+) 432 WP_254255781.1 hypothetical protein -
  MK801_RS04195 (MK801_04195) - 794991..795902 (+) 912 WP_254255782.1 CHAP domain-containing protein -
  MK801_RS04200 (MK801_04200) - 796129..796491 (+) 363 WP_057720003.1 TIGR02328 family protein -
  MK801_RS04205 (MK801_04205) - 796573..797037 (+) 465 WP_029344120.1 hypothetical protein -
  MK801_RS04210 (MK801_04210) - 797193..797438 (+) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  MK801_RS04215 (MK801_04215) - 797569..798099 (+) 531 WP_254255783.1 DUF177 domain-containing protein -
  MK801_RS04220 (MK801_04220) covR 798255..798947 (+) 693 WP_003130756.1 response regulator transcription factor Regulator
  MK801_RS04225 (MK801_04225) covS 798956..800431 (+) 1476 WP_254255784.1 ATP-binding protein Regulator
  MK801_RS04230 (MK801_04230) - 800614..801855 (+) 1242 WP_057719997.1 ammonium transporter -
  MK801_RS04235 (MK801_04235) - 801987..802328 (+) 342 WP_010906046.1 P-II family nitrogen regulator -
  MK801_RS04240 (MK801_04240) murD 802660..804012 (+) 1353 WP_057719995.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  MK801_RS04245 (MK801_04245) murG 804222..805295 (+) 1074 WP_254255785.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -

Sequence

Protein


Download         Length: 491 a.a.        Molecular weight: 56310.25 Da        Isoelectric Point: 4.7837

>NTDB_id=659970 MK801_RS04225 WP_254255784.1 798956..800431(+) (covS) [Lactococcus lactis strain 17M1]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQQLLTRSMDSVEEVLEKADAPL
NSSNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHTFGFQNQANNEMKEIRGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIIAQLIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVCNRALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIVITVYEDEQFVITSVSDKGIGISEEDIDHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEINSELGLG
STFTLKFPKIK

Nucleotide


Download         Length: 1476 bp        

>NTDB_id=659970 MK801_RS04225 WP_254255784.1 798956..800431(+) (covS) [Lactococcus lactis strain 17M1]
ATGAAAAAATTATTTACTTTCAATAAGAAAAAAGAGACGGTTGAGGAAAGTTCGGCTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTTTGTTTGCTACTTTGACTTATCAATTGACAATCAGTTCTT
TTATTAAAGAAGAACAACAATTATTAACTCGCTCTATGGATAGTGTTGAGGAAGTCTTAGAAAAAGCAGATGCTCCTTTG
AATTCATCGAATTTGAACACATATATTGAAGCGACATCAAAGATTCAAAATGGTGAGTCTGAAGGAATGAGTTTGGGTAG
TATCATTGGCACACGGAAAGCATTTTATATTTATGATTTAAATCATAAATTATTGTATTCAACGAATCGACATACTTTTG
GTTTTCAGAATCAGGCTAATAATGAAATGAAAGAGATTCGGGGAGAGAATCCAGGTTATTTAGTTCAGAGAAAAATTATT
TCTAAGTCAACAGGACAAGTTGTAGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGATTGTCTTGTTAATTTTAGAAATTGTTGCCTTGATTATCGCTCAGTTGATTGGTTATTTCATGGCTAATTACTTTA
TGAAACCATTGGAAAAGCTTTATCAGGGCATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGCGGAGATGAAATCGAAGAGTTGGCTCACGTTTACAATGATATGATGTTGAAGATGAAGGCATATCTTGAACAGCA
AAATCGCTTTGTTTCTGATGTTTCTCATGAATTAAGAACACCTTTAGCTGTCTTGGATGGACATATTAACTTGCTGAATC
GGTGGGGGAAAAATGATCCAGAAGTACTAGATGAATCATTGCAGGCAAGTTTAGATGAAGTTGATCGAATGAAGAAAATG
CTTGAGGAGATGTTGGCTCTTGCTCGTCTTGAAAATGTTGATTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCGGGCCCTTAAGAATTTTCAGCTTTTGCATGATGATTTTGAAATAGTGCTTGATAACCGGCTTATTTATCCCA
CTCATGCGCGAATTTCAGAAAATCATTTTGAACAAGGCTTAAGAATTCTGTTAGATAATGCTGCTAAATACTCTCCTGAT
GATCGTAAAGAAATCGTGATTACTGTTTATGAGGATGAACAGTTTGTGATTACGAGTGTATCTGACAAAGGAATTGGAAT
TTCAGAAGAAGATATTGATCATCTTTTTGAACGTTTCTTTAGAGCGGACAAGGCTCGCAATCGAGAAATTGGTGGAACTG
GTTTAGGTTTACCAATTTTAGCTCGATTGGCAGAAAATTATCAAGGGGAAATTGAGATAAATTCAGAACTGGGTCTTGGT
TCAACTTTTACACTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

ArlS sensor domain (ArlS_N)

(54-185)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-489)

HAMP domain (HAMP)

(208-258)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

98.982

100

0.99