Detailed information NTG0659871

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: MKW31_RS16875
• Genome accession: NZ_CP092715
• Coordinates: 3458379..3459542 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain 37-1
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3453379..3464542

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKW31_RS16845 (MKW31_16790)	-	3453643..3454062 (-)	420	WP_025285352.1	TIGR03826 family flagellar region protein	-
MKW31_RS16850 (MKW31_16795)	comFC	3454136..3454825 (-)	690	WP_217898730.1	phosphoribosyltransferase family protein	Machinery gene
MKW31_RS16855 (MKW31_16800)	-	3454831..3455115 (-)	285	WP_007407481.1	competence protein ComFB	-
MKW31_RS16860 (MKW31_16805)	comFA	3455173..3456558 (-)	1386	WP_094032535.1	DEAD/DEAH box helicase	Machinery gene
MKW31_RS16865 (MKW31_16810)	-	3456667..3457515 (-)	849	WP_003151387.1	DegV family protein	-
MKW31_RS16870 (MKW31_16815)	degU	3457613..3458302 (-)	690	WP_349403719.1	two-component system response regulator DegU	Regulator
MKW31_RS16875 (MKW31_16820)	degS	3458379..3459542 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
MKW31_RS16880 (MKW31_16825)	-	3459765..3460412 (+)	648	WP_061581228.1	YigZ family protein	-
MKW31_RS16885 (MKW31_16830)	-	3460417..3461652 (+)	1236	WP_025285355.1	LCP family protein	-
MKW31_RS16890 (MKW31_16835)	-	3461751..3462827 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
MKW31_RS16895 (MKW31_16840)	-	3462960..3464156 (-)	1197	WP_094032536.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=659871 MKW31_RS16875 WP_007407484.1 3458379..3459542(-) (degS) [Bacillus velezensis strain 37-1]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=659871 MKW31_RS16875 WP_007407484.1 3458379..3459542(-) (degS) [Bacillus velezensis strain 37-1]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951