Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG395_RS01905 Genome accession   NZ_CP108390
Coordinates   366949..367641 (+) Length   230 a.a.
NCBI ID   WP_327241302.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_01320     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 361949..372641
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG395_RS01875 (OG395_01870) - 362011..363261 (-) 1251 WP_327241299.1 IS110 family transposase -
  OG395_RS01880 (OG395_01875) - 363653..364009 (+) 357 WP_327249226.1 transposase -
  OG395_RS01885 (OG395_01880) - 363958..364179 (+) 222 Protein_375 IS6 family transposase -
  OG395_RS01890 (OG395_01885) - 364337..364486 (+) 150 Protein_376 IS256 family transposase -
  OG395_RS01895 (OG395_01890) - 364756..365676 (+) 921 WP_327241300.1 CPBP family intramembrane glutamic endopeptidase -
  OG395_RS01900 (OG395_01895) - 365785..366945 (+) 1161 WP_327241301.1 histidine kinase -
  OG395_RS01905 (OG395_01900) vraR 366949..367641 (+) 693 WP_327241302.1 response regulator transcription factor Regulator
  OG395_RS01910 (OG395_01905) - 367654..368643 (-) 990 WP_327241303.1 zinc-dependent alcohol dehydrogenase family protein -
  OG395_RS01915 (OG395_01910) - 368730..369113 (+) 384 WP_327241304.1 helix-turn-helix domain-containing protein -
  OG395_RS01920 (OG395_01915) - 369324..369478 (+) 155 Protein_382 IS6 family transposase -
  OG395_RS01925 (OG395_01920) - 369660..369884 (-) 225 WP_327241305.1 hypothetical protein -
  OG395_RS01930 (OG395_01925) - 369907..370428 (-) 522 WP_327241306.1 group II intron maturase-specific domain-containing protein -
  OG395_RS01935 (OG395_01930) - 370465..370926 (+) 462 WP_327241307.1 hypothetical protein -
  OG395_RS01940 (OG395_01935) - 370940..371146 (+) 207 WP_327241308.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 24707.53 Da        Isoelectric Point: 5.1031

>NTDB_id=659862 OG395_RS01905 WP_327241302.1 366949..367641(+) (vraR) [Streptomyces sp. NBC_01320]
MSDAPPPIRVLVCDDQALVRTGYVTIFSAQPDLEVVGEAENGHAAVQATQQLRPDVVVMDIRMPLLDGIEATRRLAGPDA
VAPPKVLVVTTFNVDAYVYDAFRAGASGFLLKDSPPAELVGGIRTVARGEALLAPAVTRHLIGHFAERLRPADTSRPARE
EVMSALTVRELEALQLIAEGLSNAEIAAAMFITPETVKTYVSRILTKLDLRDRVQAVVLAYRIGLVSATS

Nucleotide


Download         Length: 693 bp        

>NTDB_id=659862 OG395_RS01905 WP_327241302.1 366949..367641(+) (vraR) [Streptomyces sp. NBC_01320]
ATGAGCGATGCGCCGCCGCCGATCCGCGTACTCGTCTGCGACGACCAGGCATTGGTGCGCACCGGCTATGTCACCATCTT
CTCCGCCCAGCCCGACCTGGAGGTCGTCGGGGAGGCCGAGAACGGGCACGCCGCAGTCCAGGCCACGCAGCAACTACGCC
CCGACGTGGTCGTGATGGACATCCGAATGCCCCTGCTGGACGGCATCGAGGCGACCCGTCGGCTGGCCGGCCCCGACGCC
GTGGCACCACCGAAGGTACTGGTCGTCACCACCTTCAACGTCGACGCCTACGTCTACGACGCGTTCCGAGCCGGGGCGAG
CGGCTTCCTCCTCAAGGACTCGCCCCCTGCGGAGTTGGTGGGCGGCATCCGGACGGTCGCCCGGGGCGAGGCACTGCTCG
CACCGGCCGTCACCCGCCACCTCATCGGCCATTTCGCCGAACGGCTGCGCCCGGCGGACACCTCCCGGCCGGCCAGGGAG
GAAGTCATGAGCGCGCTGACCGTCCGCGAACTGGAAGCGCTCCAACTGATCGCCGAGGGACTGTCGAACGCGGAGATCGC
CGCGGCGATGTTCATCACGCCCGAGACGGTCAAGACCTATGTGTCGCGGATCCTGACCAAACTCGACCTGCGCGACCGCG
TCCAAGCCGTCGTCCTCGCCTACCGGATCGGCCTGGTATCCGCCACGTCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(10-120)

Bacterial regulatory proteins, luxR family (GerE)

(165-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.269

95.217

0.374
  degU Bacillus subtilis subsp. subtilis str. 168

37.004

98.696

0.365