Detailed information NTG0065974

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: SMUNUM_RS04485
• Genome accession: NZ_AP014571
• Coordinates: 902780..904012 (+)
• Length: 410 a.a.
• NCBI ID: WP_002262816.1
• Uniprot ID: A0AAX1K4W9
• Organism: Streptococcus mutans LP13
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 897780..909012

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUNUM_RS04460 (SMNUM_0834)	-	898852..900027 (-)	1176	WP_002282672.1	hydroxymethylglutaryl-CoA synthase	-
SMUNUM_RS04465 (SMNUM_0835)	-	900235..901074 (+)	840	WP_002267987.1	thymidylate synthase	-
SMUNUM_RS04470 (SMNUM_0836)	pnuC	901191..901970 (+)	780	WP_002264318.1	nicotinamide riboside transporter PnuC	-
SMUNUM_RS04475 (SMNUM_0837)	-	902055..902567 (+)	513	WP_002262814.1	dihydrofolate reductase	-
SMUNUM_RS04480 (SMNUM_0838)	-	902585..902755 (+)	171	WP_002262815.1	hypothetical protein	-
SMUNUM_RS04485 (SMNUM_0839)	clpX	902780..904012 (+)	1233	WP_002262816.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
SMUNUM_RS04490 (SMNUM_0840)	yihA	904028..904621 (+)	594	WP_002296921.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
SMUNUM_RS04495 (SMNUM_0841)	-	904951..906327 (+)	1377	WP_002296922.1	amino acid permease	-
SMUNUM_RS04500 (SMNUM_0842)	mmuM	906337..907287 (+)	951	WP_002269978.1	homocysteine S-methyltransferase	-
SMUNUM_RS04505 (SMNUM_0843)	-	907421..908683 (-)	1263	WP_002263804.1	PLP-dependent aminotransferase family protein	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45181.65 Da
• Isoelectric Point: 4.4495

>NTDB_id=65974 SMUNUM_RS04485 WP_002262816.1 902780..904012(+) (clpX) [Streptococcus mutans LP13]
MAGNRTNDVTVHCSFCGKNQDEVKKIIAGNGVFICNECVELSQEIIREELAEEVLADLSEVPKPKELLAILDSYVIGQDR
AKRALAVAVYNHYKRISFTESQDDQDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKKIDDQSSYMQEIISEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVKI
LTEPKNALVKQYQTLLSYDGVELEFDQEALQAIAQKAIERKTGARGLRSIIEETMLDLMFEIPSQEDVTCVRITKKAVEG
TDKPILETAS

Nucleotide

• Length: 1233 bp

>NTDB_id=65974 SMUNUM_RS04485 WP_002262816.1 902780..904012(+) (clpX) [Streptococcus mutans LP13]
ATGGCTGGAAATAGAACCAATGATGTCACAGTGCATTGTTCATTCTGTGGCAAAAATCAAGATGAAGTTAAAAAAATTAT
TGCAGGTAATGGCGTTTTTATTTGCAATGAATGTGTTGAATTATCACAAGAAATTATCCGTGAAGAACTAGCAGAAGAGG
TATTGGCTGATCTTTCAGAAGTTCCAAAACCAAAAGAATTGTTGGCAATACTAGACAGTTATGTTATCGGTCAGGACCGT
GCCAAACGTGCTTTAGCAGTTGCTGTCTATAATCATTATAAGCGTATCAGTTTTACTGAGAGCCAAGACGACCAAGATGT
TGACTTACAAAAATCAAATATTCTTATGATTGGACCGACAGGTTCTGGAAAAACTTTCTTAGCACAGACTTTGGCTAAGA
GTCTCAATGTGCCCTTTGCTATTGCTGATGCAACAGCCTTGACTGAAGCGGGTTATGTAGGTGAAGATGTTGAAAACATT
TTGCTTAAATTGATTCAGGCAGCTGATTATAATGTTGAACGCGCGGAGCGTGGCATCATTTATGTTGATGAAATTGATAA
GATTGCTAAAAAAGGCGAAAATGTTTCCATCACACGTGATGTATCTGGTGAAGGTGTCCAACAAGCTCTGCTTAAGATTA
TTGAAGGAACAGTAGCTAGTGTGCCACCACAAGGTGGTCGGAAACATCCCCAACAGGAAATGATTCAAATTGATACGAAA
AACATCCTCTTCATAGTTGGTGGCGCTTTTGATGGTATTGAAGATATCGTTAAACAGCGTTTGGGTGAGAAAATTATTGG
CTTTGGTCAAAATAATAAGAAGATTGATGATCAATCTTCTTATATGCAAGAAATTATTTCAGAAGACATTCAAAAATTTG
GTCTTATTCCAGAGTTTATTGGTCGTTTGCCAGTTTTAGCTGCGCTTGAGCAATTAACGGTTGATGATTTGGTTAAGATT
TTGACAGAACCTAAAAATGCTTTAGTTAAACAATATCAGACGCTTTTATCTTATGATGGTGTTGAGCTTGAGTTTGATCA
AGAGGCGCTTCAAGCGATTGCTCAAAAGGCGATTGAACGTAAGACAGGCGCACGCGGTCTTCGCTCTATTATTGAAGAAA
CGATGCTGGATCTGATGTTTGAAATTCCGAGTCAAGAGGATGTCACTTGCGTTCGCATTACTAAGAAAGCGGTAGAAGGG
ACCGACAAACCTATTCTTGAGACAGCTTCCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-388)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	100	100	1
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	59.102	97.805	0.578