Detailed information NTG0659405

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG311_RS21165
• Genome accession: NZ_CP108362
• Coordinates: 4629668..4630792 (-)
• Length: 374 a.a.
• NCBI ID: WP_030158457.1
• Uniprot ID: A0A5J6J8K2
• Organism: Streptomyces sp. NBC_01343
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4624668..4635792

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG311_RS21135 (OG311_21165)	cseB	4624799..4625512 (-)	714	WP_229337382.1	two-component system response regulator CseB	-
OG311_RS21140 (OG311_21170)	-	4625534..4626172 (-)	639	WP_229337380.1	hypothetical protein	-
OG311_RS21145 (OG311_21175)	-	4626211..4626783 (-)	573	WP_030867865.1	SigE family RNA polymerase sigma factor	-
OG311_RS21150 (OG311_21180)	-	4626964..4627929 (-)	966	WP_327133044.1	A/G-specific adenine glycosylase	-
OG311_RS21155 (OG311_21185)	-	4627952..4628575 (-)	624	WP_327133045.1	phosphatase PAP2 family protein	-
OG311_RS21160 (OG311_21190)	-	4628745..4629530 (+)	786	WP_327135656.1	hypothetical protein	-
OG311_RS21165 (OG311_21195)	disA	4629668..4630792 (-)	1125	WP_030158457.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG311_RS21170 (OG311_21200)	radA/sms	4630945..4632348 (-)	1404	WP_229337367.1	DNA repair protein RadA	Machinery gene
OG311_RS21175 (OG311_21205)	-	4632569..4634386 (+)	1818	WP_327133046.1	hypothetical protein	-
OG311_RS21180 (OG311_21210)	-	4634407..4635246 (-)	840	WP_327133047.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40303.32 Da
• Isoelectric Point: 5.1189

>NTDB_id=659405 OG311_RS21165 WP_030158457.1 4629668..4630792(-) (disA) [Streptomyces sp. NBC_01343]
MAAKDGAAAPGKSGASSKHDALMRASLSAVAPGQPLRDGLERIVRGNTGGLIVLGMDKAVEAMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDLTKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCGFPVVSVSQSMRLIALYVDGERRVLEESGA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELTV
GIEQERELVIRDYVPEPTAKRSRTVEEALPALDALTHPELLELAIVARALGYTGSPETLDSAVSPRGYRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQAVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=659405 OG311_RS21165 WP_030158457.1 4629668..4630792(-) (disA) [Streptomyces sp. NBC_01343]
GTGGCAGCCAAGGACGGGGCAGCAGCACCCGGGAAGTCCGGCGCGAGCTCCAAGCACGACGCGCTGATGCGCGCCTCGCT
GAGTGCGGTCGCCCCCGGTCAGCCCCTGCGCGACGGGCTGGAGCGGATCGTCCGGGGCAACACCGGCGGCCTGATCGTCC
TCGGCATGGACAAGGCCGTCGAGGCCATGTGCACGGGCGGTTTCGTCCTGGACGTGGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGAGCGCTGATCCTGGACAAGGACCTCACCAAGATCCTGCGGGCCGGCGTCCAGCTGGTGCC
GGACGCGTCGATCCCGACGGAGGAGACGGGCACCCGTCACCGCACCGCGGACCGCGTCTCGAAGCAGTGCGGTTTCCCCG
TCGTCTCGGTGTCGCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGGAGCGGCGGGTCCTGGAGGAGTCCGGGGCG
ATCCTGTCGCGGGCGAACCAGGCACTGGCCACGCTGGAGCGGTACAAGCTCCGCCTGGACGAGGTCGCCGGGACGCTGTC
CGCGCTGGAGATCGAGGACCTGGTCACGGTGCGCGACGTGACGGCGGTCGCGCAGCGGCTGGAAATGGTGCGCCGCATTG
CCACGGAAATCGCTGAATACGTGGTCGAGCTGGGCACGGACGGGCGACTGCTGTCACTCCAGCTGGACGAGCTGACGGTC
GGGATCGAGCAGGAGCGGGAGCTGGTGATCCGGGACTACGTTCCGGAGCCGACCGCGAAGCGCTCGCGCACGGTCGAGGA
GGCGCTGCCGGCACTGGACGCGCTGACGCACCCGGAGCTGCTGGAGCTGGCGATCGTGGCGCGGGCGCTGGGGTACACGG
GCTCGCCCGAGACGCTGGACTCCGCGGTGTCCCCGCGCGGGTACCGGCTGCTGGCGAAGGTCCCGCGGCTGCCGGGGGCC
ATCATCGAGCGGCTGGTCGAGCACTTCGGCGGCCTGCAGAAGCTGCTGGCCGCGAGTGTCGACGACCTCCAGGCCGTGGA
CGGCGTCGGCGAGGCCCGTGCGCGCAGCGTCCGCGAGGGGCTCTCCCGCCTCGCGGAGTCCTCGATCCTCGAACGCTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

3D structure

• AlphaFold DB: A0A5J6J8K2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.706	96.524	0.441