Detailed information    

insolico Bioinformatically predicted

Overview

Name   hapR   Type   Regulator
Locus tag   MKS89_RS02540 Genome accession   NZ_CP092587
Coordinates   549790..550410 (-) Length   206 a.a.
NCBI ID   WP_021020566.1    Uniprot ID   A0A1M5CKH9
Organism   Vibrio gazogenes strain PB1     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 544790..555410
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MKS89_RS02530 (MKS89_02530) aceF 546112..547995 (+) 1884 WP_072960052.1 pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase -
  MKS89_RS02535 (MKS89_02535) lpdA 548241..549665 (+) 1425 WP_072960050.1 dihydrolipoyl dehydrogenase -
  MKS89_RS02540 (MKS89_02540) hapR 549790..550410 (-) 621 WP_021020566.1 LuxR/HapR/OpaR family quorum-sensing transcriptional regulator Regulator
  MKS89_RS02545 (MKS89_02545) hpt 550835..551368 (+) 534 WP_072960047.1 hypoxanthine phosphoribosyltransferase -
  MKS89_RS02550 (MKS89_02550) can 551466..552134 (-) 669 WP_072960044.1 carbonate dehydratase -
  MKS89_RS02555 (MKS89_02555) - 552555..553538 (+) 984 WP_072960041.1 ABC transporter ATP-binding protein -
  MKS89_RS02560 (MKS89_02560) - 553552..554322 (+) 771 WP_072960039.1 ABC transporter permease -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 24135.49 Da        Isoelectric Point: 6.2222

>NTDB_id=659173 MKS89_RS02540 WP_021020566.1 549790..550410(-) (hapR) [Vibrio gazogenes strain PB1]
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLTHVVHQFSNFL
ADNIDVDSYIKDNLYHLTHKMTKLVFEDCHWLKVWFEWSASTRDEVWPLFVSTNHTNRLLVKNMFTNAIERGDVSDHYDP
EHLVTLFLGIFYSLFVQVNRLQDQKEIDDLVNSYLDMLCIYNNRRA

Nucleotide


Download         Length: 621 bp        

>NTDB_id=659173 MKS89_RS02540 WP_021020566.1 549790..550410(-) (hapR) [Vibrio gazogenes strain PB1]
ATGGACGCTTCAATAGAAAAACGCCCTCGTACACGATTATCACCTCAGAAACGTAAACTTCAGCTGATGGAAATTGCGCT
TGAAGTCTTCGCCAAACGGGGTATCGGACGTGGTGGACATGCAGATATCGCTGAAATTGCTCAGGTATCTGTCGCAACTG
TATTTAACTATTTCCCAACTCGTGAGGATTTAGTTGATGATGTTCTCACTCACGTCGTTCACCAGTTCTCAAACTTCCTC
GCAGACAACATCGATGTCGATAGTTATATCAAAGATAATCTCTATCATCTGACACATAAAATGACAAAACTGGTCTTTGA
AGATTGTCATTGGCTGAAAGTGTGGTTTGAATGGAGTGCATCGACCCGCGACGAAGTCTGGCCGTTATTCGTATCGACCA
ACCATACAAACCGTCTGTTGGTAAAAAATATGTTTACCAATGCAATCGAACGCGGCGATGTCAGCGATCATTATGATCCT
GAACATTTAGTCACGCTGTTCCTCGGAATTTTCTATTCCCTGTTTGTACAAGTGAACCGTTTACAAGATCAAAAAGAGAT
CGATGATCTCGTGAACAGCTACTTGGACATGTTATGCATTTATAACAACCGTCGGGCTTAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, tetR family (TetR_N)

(23-67)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1M5CKH9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hapR Vibrio cholerae C6706

73.892

98.544

0.728
  hapR Vibrio cholerae strain A1552

73.892

98.544

0.728
  opaR Vibrio parahaemolyticus RIMD 2210633

75.377

96.602

0.728