Detailed information NTG0658749

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MKI61_RS14060
• Genome accession: NZ_CP092554
• Coordinates: 2795750..2796637 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain VMRSA-WC071
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2790750..2801637

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKI61_RS14030 (MKI61_002788)	-	2790769..2790861 (+)	93	WP_010956583.1	hypothetical protein	-
MKI61_RS14035 (MKI61_002789)	-	2790969..2791466 (-)	498	WP_001065268.1	glutathione peroxidase	-
MKI61_RS14040 (MKI61_002790)	-	2791476..2791736 (-)	261	WP_001791974.1	hypothetical protein	-
MKI61_RS14045 (MKI61_002791)	-	2792118..2792231 (-)	114	Protein_2733	hypothetical protein	-
MKI61_RS14050 (MKI61_002792)	-	2792890..2794890 (-)	2001	WP_000776751.1	ABC transporter permease	-
MKI61_RS14055 (MKI61_002793)	-	2794887..2795642 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
MKI61_RS14060 (MKI61_002794)	braS	2795750..2796637 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MKI61_RS14065 (MKI61_002795)	braR	2796648..2797313 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MKI61_RS14070 (MKI61_002796)	-	2797339..2797539 (-)	201	WP_000604730.1	hypothetical protein	-
MKI61_RS14075 (MKI61_002797)	-	2797737..2799161 (+)	1425	WP_000953755.1	alkaline phosphatase	-
MKI61_RS14080 (MKI61_002798)	-	2799231..2799341 (+)	111	Protein_2740	hypothetical protein	-
MKI61_RS14085 (MKI61_002799)	-	2799444..2799899 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MKI61_RS14090 (MKI61_002800)	-	2800144..2800905 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=658749 MKI61_RS14060 WP_000143425.1 2795750..2796637(-) (braS) [Staphylococcus aureus strain VMRSA-WC071]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=658749 MKI61_RS14060 WP_000143425.1 2795750..2796637(-) (braS) [Staphylococcus aureus strain VMRSA-WC071]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1