Detailed information NTG0658745

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OHA58_RS15290
• Genome accession: NZ_CP108312
• Coordinates: 3426228..3427352 (+)
• Length: 374 a.a.
• NCBI ID: WP_127832608.1
• Uniprot ID: A0A437P3D3
• Organism: Streptomyces sp. NBC_00009
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3421228..3432352

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHA58_RS15275 (OHA58_15295)	-	3421749..3422678 (+)	930	WP_405479190.1	hypothetical protein	-
OHA58_RS15280 (OHA58_15300)	-	3422710..3424428 (-)	1719	WP_405479191.1	BACON domain-containing protein	-
OHA58_RS15285 (OHA58_15305)	radA/sms	3424706..3426115 (+)	1410	WP_405479193.1	DNA repair protein RadA	Machinery gene
OHA58_RS15290 (OHA58_15310)	disA	3426228..3427352 (+)	1125	WP_127832608.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OHA58_RS15295 (OHA58_15315)	-	3427797..3428597 (-)	801	WP_405479195.1	hypothetical protein	-
OHA58_RS15300 (OHA58_15320)	-	3428783..3429424 (+)	642	WP_405479197.1	phosphatase PAP2 family protein	-
OHA58_RS15305 (OHA58_15325)	-	3429425..3429724 (-)	300	Protein_3039	response regulator transcription factor	-
OHA58_RS15310 (OHA58_15330)	-	3429855..3429929 (-)	75	Protein_3040	hypothetical protein	-
OHA58_RS15315 (OHA58_15335)	-	3429902..3430300 (-)	399	WP_405479198.1	hypothetical protein	-
OHA58_RS15320 (OHA58_15340)	-	3430444..3431340 (+)	897	WP_405479200.1	A/G-specific adenine glycosylase	-
OHA58_RS15325 (OHA58_15345)	-	3431522..3432070 (+)	549	WP_405479202.1	SigE family RNA polymerase sigma factor	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40327.18 Da
• Isoelectric Point: 4.9269

>NTDB_id=658745 OHA58_RS15290 WP_127832608.1 3426228..3427352(+) (disA) [Streptomyces sp. NBC_00009]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGWDKTVESMCTGGFILDVEFTATRLR
ELCKLDGGIVIDKDITKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVSFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALFELDALTHAELLELPTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=658745 OHA58_RS15290 WP_127832608.1 3426228..3427352(+) (disA) [Streptomyces sp. NBC_00009]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGCAAGTCCGGCGGGAGCTCCGGTGCCGATGGGCTGATGCGCGCCTCACT
GAGCGCGGTCGCGCCCGGTACGGCGCTGCGTGACGGCCTCGAGCGAATCCTCCGCGGCAACACCGGCGGACTCATCGTTC
TCGGCTGGGACAAGACCGTCGAGTCGATGTGTACCGGCGGTTTCATCCTGGACGTCGAGTTCACCGCGACGCGCCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTCATCGACAAGGACATCACCAAGATCCTGCGGGCGGGCGTCCAGTTGGTGCC
CGACCCCACGATCCCCACGGAGGAGACGGGCACGCGGCACCGCACCGCGGACCGGGTGAGCAAGCAGGTCAGCTTCCCCG
TGGTCTCGGTGTCGCAGTCGATGCGGCTCATCGCCCTTTACGTGGACGGGCAGCGGCGCGTTCTCGAGGACTCGGCCGCG
ATTCTCTCGCGTGCGAATCAGGCTCTCGCCACTCTTGAGCGGTACAAGCTCCGCTTGGACGAGGTGGCCGGGACGCTCTC
CGCGCTCGAGATCGAGGATCTCGTGACCGTGCGGGATGTGACCGCGGTCGCGCAGCGGCTGGAGATGGTGCGGCGCATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTCGGGACGGATGGGCGACTGCTCGCCCTTCAGCTCGACGAGTTGATCGCC
GGGGTGGAGCCCGAGCGGGAGCTCGTCGTTCGGGACTACGTGCCCGAACCTACGGCCAAGCGGTCCCGGACCGTTGATGA
GGCGCTCTTCGAACTCGACGCTCTGACGCATGCCGAGCTTCTCGAACTGCCTACTGTGGCACGTGCGTTGGGGTACACCG
GGTCTCCGGAGACCTTGGACTCGGCTGTTTCGCCTCGTGGGTTCCGGCTGTTGGCGAAGGTGCCTCGGCTGCCCGGGGCC
ATCATTGACCGGCTTGTCGAGCACTTCGGGGGGCTGCAGAAGCTGCTCGCCGCCAGCGTCGATGATCTGCAGACGGTGGA
CGGCGTCGGGGAGGCCCGTGCCCGGAGCGTGCGGGAAGGGCTCTCGCGGTTGGCCGAGTCGTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

3D structure

• AlphaFold DB: A0A437P3D3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	44.598	96.524	0.43