Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA19_RS21815 Genome accession   NZ_CP108309
Coordinates   4731909..4732586 (+) Length   225 a.a.
NCBI ID   WP_353790693.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00012     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4726909..4737586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA19_RS21795 (OHA19_21705) - 4727260..4728108 (+) 849 WP_405714185.1 tryptophan 2,3-dioxygenase family protein -
  OHA19_RS21800 (OHA19_21710) kynU 4728101..4729333 (+) 1233 WP_405714183.1 kynureninase -
  OHA19_RS21805 (OHA19_21715) - 4729607..4730482 (+) 876 WP_405714181.1 alpha/beta hydrolase family protein -
  OHA19_RS21810 (OHA19_21720) - 4730587..4731912 (+) 1326 WP_405714179.1 sensor histidine kinase -
  OHA19_RS21815 (OHA19_21725) vraR 4731909..4732586 (+) 678 WP_353790693.1 response regulator Regulator
  OHA19_RS21820 (OHA19_21730) - 4732713..4733942 (+) 1230 WP_405714177.1 cytochrome P450 -
  OHA19_RS21825 (OHA19_21735) - 4734111..4734437 (-) 327 WP_405714175.1 hypothetical protein -
  OHA19_RS21830 (OHA19_21740) - 4734521..4736155 (-) 1635 WP_405751223.1 ABC transporter permease -
  OHA19_RS21835 (OHA19_21745) - 4736152..4737084 (-) 933 WP_405751225.1 ATP-binding cassette domain-containing protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24141.93 Da        Isoelectric Point: 4.9545

>NTDB_id=658683 OHA19_RS21815 WP_353790693.1 4731909..4732586(+) (vraR) [Streptomyces sp. NBC_00012]
MSTPTAPSIRVLIVDDQMMVREGFSVLLNAMPGIEVVGEAVDGRQAIAQVAALRPDVVLMDIRMPELNGIEATREIVAAD
ADAKVLVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPTVTKRLINEFSKLAETPRSPALARVG
DLTERETEVLVLIAQGRSNAEIASHLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPS

Nucleotide


Download         Length: 678 bp        

>NTDB_id=658683 OHA19_RS21815 WP_353790693.1 4731909..4732586(+) (vraR) [Streptomyces sp. NBC_00012]
ATGAGCACTCCCACCGCCCCGTCCATCCGGGTGCTGATCGTGGACGACCAGATGATGGTCCGTGAGGGCTTCTCGGTACT
CCTCAACGCCATGCCGGGGATCGAGGTCGTCGGCGAGGCCGTCGACGGCCGGCAGGCCATCGCACAGGTCGCCGCGCTGC
GCCCCGACGTGGTCCTGATGGACATCCGGATGCCGGAACTCAACGGCATCGAGGCCACCCGCGAGATCGTCGCCGCCGAC
GCGGACGCCAAGGTCCTGGTGCTGACCACCTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGCGCCGGGGCGTCCGG
CTTCCTCCTCAAGGACGCCTCCGCGCGCCAGCTCGCGGACGGGGTACGGGTGGTGGCCGCGGGCGAGGCGCTGCTCGCGC
CGACCGTCACCAAGCGGCTGATCAACGAGTTCTCGAAGCTCGCGGAGACCCCGCGTTCGCCCGCGCTGGCCCGGGTCGGC
GACCTCACCGAGCGCGAGACGGAGGTGCTCGTCCTCATCGCGCAGGGCCGGTCCAACGCCGAGATCGCCTCGCATCTGGT
GGTCGCCGAGTCCACCATCAAGACCCATGTGAGCCGGATCCTGGTGAAGCTGGGGCTGCGCGACCGCACCCAGGCGGCCG
TCTTCGCGTACGAGGCCCGGCTGGTCACACCTTCTTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(162-216)

Response regulator receiver domain (Response_reg)

(11-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.116

95.556

0.431
  degU Bacillus subtilis subsp. subtilis str. 168

43.119

96.889

0.418