Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   OG235_RS23615 Genome accession   NZ_CP108298
Coordinates   5388347..5389471 (+) Length   374 a.a.
NCBI ID   WP_037702381.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00024     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 5383347..5394471
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG235_RS23605 (OG235_23550) - 5385225..5386610 (+) 1386 WP_327728326.1 alpha/beta hydrolase -
  OG235_RS23610 (OG235_23555) radA/sms 5386856..5388265 (+) 1410 WP_326579303.1 DNA repair protein RadA Machinery gene
  OG235_RS23615 (OG235_23560) disA 5388347..5389471 (+) 1125 WP_037702381.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  OG235_RS23620 (OG235_23565) - 5389693..5390538 (-) 846 WP_326579308.1 hypothetical protein -
  OG235_RS23625 (OG235_23570) - 5390934..5391992 (+) 1059 WP_328223799.1 LLM class flavin-dependent oxidoreductase -
  OG235_RS23630 (OG235_23575) - 5392196..5393113 (+) 918 WP_326579311.1 A/G-specific adenine glycosylase -
  OG235_RS23635 (OG235_23580) - 5393517..5394068 (+) 552 WP_326579312.1 SigE family RNA polymerase sigma factor -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40150.94 Da        Isoelectric Point: 5.1026

>NTDB_id=658318 OG235_RS23615 WP_037702381.1 5388347..5389471(+) (disA) [Streptomyces sp. NBC_00024]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGFDKTVEPMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLVALYVDGHRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALRELDALTHAELLELPTVARALGYTGSPEGMDSAVSPRGYRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=658318 OG235_RS23615 WP_037702381.1 5388347..5389471(+) (disA) [Streptomyces sp. NBC_00024]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGCTCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCCGTGGCACCAGGTACGGCCCTGCGCGACGGGCTTGAGCGGATTCTCCGCGGCAACACCGGCGGACTCATCGTGC
TCGGCTTCGACAAGACCGTCGAGCCGATGTGCACCGGTGGATTCGTCCTGGATGTCGAGTTCACGGCCACGCGCCTGCGT
GAGCTGTGCAAGCTCGACGGCGGCATCGTCCTGTCCTCGGATCTCTCCAAGATCCTCCGGGCGGGCGTCCAACTGGTCCC
GGACCCCACGATCCCCACCGAGGAGACGGGCACCCGGCACCGCACGGCGGACCGCGTCAGCAAACAGGTCGGCTTCCCGG
TCGTCTCGGTCTCCCAGTCGATGCGCCTGGTCGCGCTGTACGTCGACGGTCACCGGCGGGTCCTGGAGGACTCGGCGGCG
ATCCTGTCCCGCGCGAACCAGGCCCTGGCGACCCTGGAGCGGTACAAGCTCCGCCTGGACGAGGTGGCGGGCACCCTCTC
CGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTCTCGGCGGTCGCCCAGCGACTGGAGATGGTCCGGCGCATCG
CCACCGAAATCGCCGAATACGTGGTCGAACTGGGCACGGACGGCCGTCTCCTGGCCCTCCAGCTCGACGAACTGATCGCG
GGCGTCGAACCGGAGCGCGAACTGGTCGTCCGGGACTACGTCCCCGAGCCGACGGCCAAACGCTCCCGCACGGTCGACGA
GGCCCTCCGCGAACTCGACGCCCTCACCCACGCGGAGCTCCTCGAACTCCCCACGGTGGCCCGCGCCCTCGGCTACACCG
GCTCCCCCGAGGGCATGGACTCCGCCGTCTCCCCGCGCGGCTACCGCCTCCTGGCCAAGGTCCCCCGCCTCCCCGGCGCC
ATCATCGACCGCCTCGTCGAGCACTTCGGCGGCCTCCAGAAACTCCTCGCCGCCAGCGTCGACGACCTCCAGACGGTCGA
CGGAGTGGGCGAGGCCCGCGCACGCAGCGTCCGCGAGGGCCTGTCACGACTGGCGGAGTCGTCGATCCTGGAGCGCTACG
TCTAG

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-295)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.152

96.524

0.436