Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   MKD39_RS09135 Genome accession   NZ_CP092478
Coordinates   1876779..1877363 (+) Length   194 a.a.
NCBI ID   WP_011276196.1    Uniprot ID   A0A2A1KAP4
Organism   Staphylococcus haemolyticus strain CGMH-SH51     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1877998..1885460 1876779..1877363 flank 635


Gene organization within MGE regions


Location: 1876779..1885460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MKD39_RS09135 (MKD39_09125) comK/comK1 1876779..1877363 (+) 585 WP_011276196.1 competence protein ComK Regulator
  MKD39_RS09150 (MKD39_09140) - 1877998..1879666 (+) 1669 Protein_1778 IS1182 family transposase -
  MKD39_RS09155 (MKD39_09145) - 1880191..1880700 (+) 510 WP_033079859.1 PH domain-containing protein -
  MKD39_RS09160 (MKD39_09150) - 1880735..1881310 (+) 576 WP_033079858.1 hypothetical protein -
  MKD39_RS09165 (MKD39_09155) - 1881398..1881481 (+) 84 WP_227528431.1 Ltp family lipoprotein -
  MKD39_RS09170 (MKD39_09160) - 1881529..1882518 (-) 990 WP_033079857.1 lipoate--protein ligase -
  MKD39_RS09175 (MKD39_09165) - 1882719..1882895 (+) 177 WP_011276202.1 YkvS family protein -
  MKD39_RS09180 (MKD39_09170) - 1882912..1883514 (+) 603 WP_011276203.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  MKD39_RS09185 (MKD39_09175) - 1883787..1885455 (+) 1669 Protein_1785 IS1182 family transposase -

Sequence

Protein


Download         Length: 194 a.a.        Molecular weight: 23002.43 Da        Isoelectric Point: 9.2942

>NTDB_id=657949 MKD39_RS09135 WP_011276196.1 1876779..1877363(+) (comK/comK1) [Staphylococcus haemolyticus strain CGMH-SH51]
MTNISQSQNTVYIIRKGDMIIKPVIDDYEQTKGSEIWKYDSTIVSSPFKTQKIVERSCKFYGNSYISKKSETQRIAGITS
KPPILLTPLFPTYFFPTHSDRLEENMWINMHYVHEIKPLKNRKCKIIFANHQTLTLNVSYHSIWHQYSNCIFYYYMVDKQ
SRMKSNNPEMPIDYEKTTLNIFEALSHYSLLQDK

Nucleotide


Download         Length: 585 bp        

>NTDB_id=657949 MKD39_RS09135 WP_011276196.1 1876779..1877363(+) (comK/comK1) [Staphylococcus haemolyticus strain CGMH-SH51]
ATGACAAATATTTCTCAAAGCCAAAATACTGTATATATTATTCGAAAAGGAGATATGATAATCAAACCCGTCATTGATGA
TTATGAGCAAACAAAAGGATCAGAAATATGGAAATATGATTCCACAATAGTTTCAAGCCCATTCAAAACTCAAAAAATCG
TCGAACGCTCATGTAAATTTTATGGTAATAGCTATATTAGTAAGAAATCCGAAACACAACGAATTGCCGGCATTACTAGT
AAACCACCTATTTTATTGACTCCTCTCTTCCCCACTTATTTTTTCCCTACACATTCAGACCGTTTAGAAGAAAACATGTG
GATTAATATGCATTATGTACATGAAATTAAACCTCTTAAAAATCGAAAATGTAAAATTATTTTTGCAAATCATCAAACAT
TAACACTTAATGTTTCCTACCACAGTATTTGGCACCAATACTCTAACTGCATTTTTTATTATTACATGGTCGATAAACAA
TCTCGTATGAAGTCAAACAATCCAGAAATGCCAATAGATTATGAGAAAACGACTTTAAATATTTTCGAAGCACTTTCACA
TTATTCACTATTACAAGATAAATAG

Domains

Predicted by InterproScan.

ComK protein (ComK)

(11-161)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2A1KAP4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

68.617

96.907

0.665
  comK/comK1 Staphylococcus aureus N315

68.617

96.907

0.665