Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   MKD48_RS11545 Genome accession   NZ_CP092475
Coordinates   2279030..2279599 (-) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain P5     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2274030..2284599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MKD48_RS11505 - 2274504..2275112 (-) 609 WP_000020302.1 class I SAM-dependent methyltransferase -
  MKD48_RS11510 rplL 2275287..2275655 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  MKD48_RS11515 rplJ 2275698..2276198 (-) 501 WP_001273087.1 50S ribosomal protein L10 -
  MKD48_RS11520 rplA 2276470..2277162 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  MKD48_RS11525 rplK 2277370..2277792 (-) 423 WP_001085795.1 50S ribosomal protein L11 -
  MKD48_RS11530 nusG 2277973..2278521 (-) 549 WP_001288298.1 transcription termination/antitermination protein NusG -
  MKD48_RS11535 secE 2278534..2278716 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  MKD48_RS11540 rpmG 2278772..2278915 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  MKD48_RS11545 sigH 2279030..2279599 (-) 570 WP_000872873.1 RNA polymerase sigma factor Regulator
  MKD48_RS11550 - 2279680..2280204 (-) 525 WP_000664732.1 NYN domain-containing protein -
  MKD48_RS11555 rlmB 2280204..2280950 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  MKD48_RS11560 - 2280958..2281362 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  MKD48_RS11565 cysS 2281355..2282755 (-) 1401 WP_000631963.1 cysteine--tRNA ligase -
  MKD48_RS11570 cysE 2282739..2283386 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=657914 MKD48_RS11545 WP_000872873.1 2279030..2279599(-) (sigH) [Staphylococcus aureus strain P5]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=657914 MKD48_RS11545 WP_000872873.1 2279030..2279599(-) (sigH) [Staphylococcus aureus strain P5]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984