Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   MH925_RS05900 Genome accession   NZ_CP092412
Coordinates   1131333..1131989 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain HNU24     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1126333..1136989
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MH925_RS05870 oppF 1126862..1127779 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  MH925_RS05875 - 1127886..1129082 (+) 1197 WP_012117284.1 putative glycoside hydrolase -
  MH925_RS05880 - 1129191..1129769 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  MH925_RS05885 spx 1129948..1130343 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  MH925_RS05890 - 1130401..1131057 (-) 657 WP_012117285.1 TerC family protein -
  MH925_RS05895 - 1131240..1131350 (+) 111 Protein_1090 adaptor protein MecA -
  MH925_RS05900 mecA 1131333..1131989 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  MH925_RS05905 - 1132140..1133300 (+) 1161 WP_012117286.1 competence protein CoiA family protein -
  MH925_RS05910 pepF 1133528..1135357 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  MH925_RS05915 - 1135395..1135562 (-) 168 WP_003155026.1 hypothetical protein -
  MH925_RS05920 spxH 1135848..1136750 (-) 903 WP_012117287.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=657224 MH925_RS05900 WP_003155032.1 1131333..1131989(+) (mecA) [Bacillus velezensis strain HNU24]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=657224 MH925_RS05900 WP_003155032.1 1131333..1131989(+) (mecA) [Bacillus velezensis strain HNU24]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
GGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895