Detailed information NTG0656294

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OHB59_RS21585
• Genome accession: NZ_CP108206
• Coordinates: 4811315..4812439 (+)
• Length: 374 a.a.
• NCBI ID: WP_266673013.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00110
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4806315..4817439

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHB59_RS21570 (OHB59_21520)	-	4806868..4807800 (+)	933	WP_389564569.1	hypothetical protein	-
OHB59_RS21575 (OHB59_21525)	-	4807833..4809548 (-)	1716	WP_266673017.1	BACON domain-containing protein	-
OHB59_RS21580 (OHB59_21530)	radA/sms	4809793..4811202 (+)	1410	WP_266673015.1	DNA repair protein RadA	Machinery gene
OHB59_RS21585 (OHB59_21535)	disA	4811315..4812439 (+)	1125	WP_266673013.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OHB59_RS21590 (OHB59_21540)	-	4813129..4813923 (-)	795	WP_405599932.1	hypothetical protein	-
OHB59_RS21595 (OHB59_21545)	-	4814109..4814750 (+)	642	WP_266673011.1	phosphatase PAP2 family protein	-
OHB59_RS21600 (OHB59_21550)	-	4814751..4815398 (-)	648	WP_330279732.1	response regulator transcription factor	-
OHB59_RS21605 (OHB59_21555)	-	4815395..4816993 (-)	1599	WP_405599936.1	sensor histidine kinase	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40341.21 Da
• Isoelectric Point: 4.9304

>NTDB_id=656294 OHB59_RS21585 WP_266673013.1 4811315..4812439(+) (disA) [Streptomyces sp. NBC_00110]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGWDKTVESMCTGGFILDVEFTATRLR
ELCKLDGGIVIDKDITKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVSFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALFELDALTHAELLELPTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=656294 OHB59_RS21585 WP_266673013.1 4811315..4812439(+) (disA) [Streptomyces sp. NBC_00110]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGCAAGTCCGGCGGGAGCTCCGGTGCCGATGGGCTGATGCGCGCCTCACT
GAGCGCGGTCGCGCCCGGTACGGCGCTGCGTGACGGCCTCGAGCGAATCCTCCGCGGCAACACCGGCGGACTCATCGTTC
TCGGCTGGGACAAGACCGTCGAGTCGATGTGTACCGGCGGTTTCATCCTGGACGTCGAGTTCACCGCGACGCGCCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTCATCGACAAGGACATCACCAAGATCCTGCGGGCGGGCGTCCAGTTGGTGCC
CGACCCCACGATCCCCACGGAGGAGACGGGCACGCGGCACCGCACCGCGGACCGGGTGAGCAAGCAGGTCAGCTTCCCCG
TGGTCTCGGTGTCGCAGTCGATGCGGCTCATCGCCCTCTACGTGGACGGGCAGCGGCGCGTCCTCGAGGACTCGGCCGCG
ATTCTCTCGCGGGCGAATCAGGCGCTGGCCACTCTTGAGCGGTACAAGCTCCGCTTGGACGAGGTGGCCGGGACACTCTC
CGCGCTCGAGATCGAGGATCTCGTGACCGTGCGGGATGTGACCGCGGTCGCGCAGCGGCTGGAAATGGTGCGGCGCATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTCGGGACGGATGGGCGACTGCTCGCCCTTCAGCTCGACGAGTTGATCGCC
GGGGTGGAGCCGGAGCGGGAGCTCGTCGTTCGGGACTACGTGCCCGAACCCACGGCCAAGCGGTCCCGGACCGTCGACGA
GGCCCTGTTCGAACTCGACGCGCTGACGCATGCCGAGCTTCTCGAACTGCCCACTGTGGCACGCGCGTTGGGGTACACCG
GGTCTCCGGAGACCCTGGACTCGGCCGTTTCGCCTCGTGGGTTCCGGCTGTTGGCGAAGGTGCCTCGGCTGCCCGGGGCC
ATCATTGAGCGGCTTGTCGAGCACTTCGGGGGGCTGCAGAAGCTGCTCGCCGCCAGCGTCGACGATCTGCAGACCGTGGA
CGGCGTCGGCGAGGCCCGCGCCCGGAGCGTGCGGGAAGGGCTCTCGCGGTTGGCCGAGTCGTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	44.875	96.524	0.433