Detailed information NTG0655969

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: LGL65_RS13355
• Genome accession: NZ_CP092110
• Coordinates: 2608030..2609193 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain LOH112
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2603030..2614193

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LGL65_RS13335	-	2603458..2604654 (+)	1197	WP_237586812.1	glycosyltransferase	-
LGL65_RS13340	-	2604786..2605862 (+)	1077	WP_003151382.1	MraY family glycosyltransferase	-
LGL65_RS13345	-	2605962..2607155 (-)	1194	WP_151140083.1	LCP family protein	-
LGL65_RS13350	-	2607160..2607807 (-)	648	WP_007407485.1	YigZ family protein	-
LGL65_RS13355	degS	2608030..2609193 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
LGL65_RS13360	degU	2609270..2609959 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
LGL65_RS13365	-	2610057..2610905 (+)	849	WP_237586810.1	DegV family protein	-
LGL65_RS13370	comFA	2611013..2612398 (+)	1386	WP_237586808.1	DEAD/DEAH box helicase	Machinery gene
LGL65_RS13375	-	2612456..2612740 (+)	285	WP_017418816.1	competence protein ComFB	-
LGL65_RS13380	comFC	2612746..2613435 (+)	690	WP_217425079.1	phosphoribosyltransferase family protein	Machinery gene
LGL65_RS13385	-	2613509..2613928 (+)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=655969 LGL65_RS13355 WP_007407484.1 2608030..2609193(+) (degS) [Bacillus velezensis strain LOH112]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=655969 LGL65_RS13355 WP_007407484.1 2608030..2609193(+) (degS) [Bacillus velezensis strain LOH112]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGAAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCAGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951