Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG941_RS12450 Genome accession   NZ_CP108172
Coordinates   2584848..2585498 (+) Length   216 a.a.
NCBI ID   WP_326714152.1    Uniprot ID   A0ABV4SPB0
Organism   Streptomyces sp. NBC_00147     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2579848..2590498
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG941_RS12425 (OG941_12395) - 2580388..2581194 (-) 807 WP_326714157.1 SAM-dependent methyltransferase -
  OG941_RS12430 (OG941_12400) - 2581285..2581719 (-) 435 WP_326714156.1 hypothetical protein -
  OG941_RS12435 (OG941_12405) - 2581783..2582520 (-) 738 WP_326714155.1 ABC transporter permease -
  OG941_RS12440 (OG941_12410) - 2582523..2583452 (-) 930 WP_406427393.1 ATP-binding cassette domain-containing protein -
  OG941_RS12445 (OG941_12415) - 2583561..2584802 (+) 1242 WP_328542879.1 histidine kinase -
  OG941_RS12450 (OG941_12420) vraR 2584848..2585498 (+) 651 WP_326714152.1 response regulator transcription factor Regulator
  OG941_RS12455 (OG941_12425) - 2585618..2586775 (+) 1158 WP_328542878.1 ROK family transcriptional regulator -
  OG941_RS12460 (OG941_12430) - 2586866..2587633 (-) 768 WP_227293472.1 GntR family transcriptional regulator -
  OG941_RS12465 (OG941_12435) - 2587893..2588771 (-) 879 WP_406427395.1 RNA polymerase sigma-70 factor -
  OG941_RS12470 (OG941_12440) - 2588955..2589785 (+) 831 WP_327576936.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23066.65 Da        Isoelectric Point: 4.9654

>NTDB_id=655286 OG941_RS12450 WP_326714152.1 2584848..2585498(+) (vraR) [Streptomyces sp. NBC_00147]
MPLTVLLVDDEPLVRAGLRAVLSAQPDIEVVGEAADGAAVIPLVRQLRPDVVAMDVRMPLLDGIEATRAVLRSVSEPPKI
LVITTFENDEYVYGALRAGADGFLLKRSRPAEIVNAVRLVAEGDSLLFPAAVRRLAAEYGNTSAREAMDRAALTEREAEV
LRLMTRGLSNAEIAVRLVVGTETVKSHVSAVLAKLGARDRTQAVIAAYESGFVSPG

Nucleotide


Download         Length: 651 bp        

>NTDB_id=655286 OG941_RS12450 WP_326714152.1 2584848..2585498(+) (vraR) [Streptomyces sp. NBC_00147]
ATGCCGCTCACCGTGCTTCTTGTCGACGATGAACCGCTGGTCCGCGCGGGGTTGCGTGCCGTGCTCTCGGCGCAGCCGGA
CATCGAGGTGGTGGGCGAGGCGGCCGACGGTGCCGCGGTGATCCCGCTCGTCCGACAGCTGCGTCCGGATGTGGTCGCCA
TGGATGTGCGCATGCCTCTCCTGGACGGGATCGAGGCCACGCGCGCGGTGCTGCGCAGTGTGTCCGAGCCGCCCAAGATC
CTGGTCATCACGACGTTCGAGAACGACGAGTACGTGTACGGGGCGCTGCGGGCGGGCGCCGACGGGTTCCTGCTGAAGCG
GTCGCGGCCCGCCGAGATCGTGAACGCGGTCCGGCTCGTGGCCGAGGGCGATTCCCTACTGTTCCCCGCGGCCGTGCGGA
GGCTCGCGGCCGAGTACGGCAACACGTCGGCACGCGAGGCGATGGACCGCGCCGCGCTCACGGAGCGGGAGGCGGAGGTG
CTGCGCCTGATGACGCGGGGCCTGTCCAACGCGGAGATCGCCGTGCGGCTCGTCGTCGGCACGGAGACGGTCAAGTCGCA
TGTGAGCGCCGTCCTCGCCAAGCTCGGGGCACGGGACCGGACACAGGCCGTCATCGCCGCGTACGAGTCCGGTTTCGTGT
CGCCCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(152-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.654

99.074

0.403
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.375