Detailed information NTG0655159

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG553_RS19020
• Genome accession: NZ_CP108161
• Coordinates: 4115808..4116932 (-)
• Length: 374 a.a.
• NCBI ID: WP_405980131.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00158
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4110808..4121932

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG553_RS18995 (OG553_18960)	-	4111487..4112140 (-)	654	WP_405980127.1	hypothetical protein	-
OG553_RS19000 (OG553_18965)	-	4112179..4112739 (-)	561	WP_007264805.1	SigE family RNA polymerase sigma factor	-
OG553_RS19005 (OG553_18970)	-	4112966..4113901 (-)	936	WP_405980128.1	A/G-specific adenine glycosylase	-
OG553_RS19010 (OG553_18975)	-	4113925..4114545 (-)	621	WP_405980129.1	phosphatase PAP2 family protein	-
OG553_RS19015 (OG553_18980)	-	4114706..4115503 (+)	798	WP_405980130.1	hypothetical protein	-
OG553_RS19020 (OG553_18985)	disA	4115808..4116932 (-)	1125	WP_405980131.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG553_RS19025 (OG553_18990)	radA/sms	4117234..4118649 (-)	1416	WP_405980132.1	DNA repair protein RadA	Machinery gene
OG553_RS19030 (OG553_18995)	-	4119066..4120799 (+)	1734	WP_405980133.1	BACON domain-containing protein	-
OG553_RS19035 (OG553_19000)	-	4120822..4121625 (-)	804	WP_405980134.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40309.32 Da
• Isoelectric Point: 5.1222

>NTDB_id=655159 OG553_RS19020 WP_405980131.1 4115808..4116932(-) (disA) [Streptomyces sp. NBC_00158]
MAAKDGAAASGKSGASSKHEALMRASLSAVAPGQPLRDGLERIVRGNTGGLIVLGMDKAVEAMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCGFPVVSVSQSMRLIALYVDGERRVLEESGA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELTV
GIEQERELVIRDYVPEPTAKRSRTVEEALPALDALTHPELLELAIVAKALGYTGSPETLDSAVSPRGYRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=655159 OG553_RS19020 WP_405980131.1 4115808..4116932(-) (disA) [Streptomyces sp. NBC_00158]
GTGGCAGCCAAGGACGGGGCAGCAGCATCCGGGAAGTCCGGCGCGAGCTCCAAGCACGAGGCGTTGATGCGCGCCTCGCT
GAGCGCGGTCGCGCCTGGTCAGCCCCTGCGCGACGGGCTGGAGCGGATCGTCCGCGGCAACACGGGCGGTTTGATCGTCC
TGGGCATGGACAAGGCCGTCGAGGCGATGTGCACCGGCGGCTTCGTACTGGACGTGGAGTTCACCGCGACCCGGCTGCGG
GAGCTGTGCAAGCTCGACGGGGCGCTCATCCTCGACAAGGACATCACCAAGATCCTGCGGGCCGGCGTACAGCTGGTGCC
CGACGCGTCGATCCCCACGGAGGAGACGGGCACCCGTCACCGCACGGCGGACCGCGTCTCCAAGCAGTGCGGCTTCCCGG
TGGTGTCGGTGTCGCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGCGAGCGGCGGGTCCTGGAGGAGTCCGGGGCG
ATCCTGTCGCGCGCGAACCAGGCGCTGGCCACGCTGGAGCGGTACAAGCTCCGCCTGGACGAGGTCGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTCACGGTCCGCGACGTGACCGCCGTCGCGCAGCGGCTGGAAATGGTCCGCCGGATCG
CGACGGAAATCGCCGAGTACGTGGTCGAACTGGGCACGGACGGGCGACTGCTCTCGCTCCAGCTGGACGAGCTGACGGTC
GGCATCGAGCAGGAACGGGAGCTGGTGATCCGGGACTACGTTCCGGAACCGACGGCGAAGCGTTCCCGCACGGTGGAGGA
GGCGCTGCCGGCACTGGACGCGCTGACGCATCCGGAACTGCTGGAGCTGGCGATCGTGGCGAAGGCGCTCGGGTACACGG
GCTCGCCGGAGACCCTGGACTCGGCGGTGTCGCCCCGCGGGTACCGGCTGCTGGCGAAGGTTCCGAGGCTGCCGGGGGCG
ATCATCGAGCGGCTGGTGGAGCACTTCGGCGGGCTGCAGAAACTGCTGGCGGCGTCGGTGGACGACCTCCAGACGGTGGA
CGGCGTCGGCGAGGCGCGTGCGCGCAGCGTCCGCGAGGGGTTGTCCCGCCTGGCGGAGTCCTCGATCCTCGAACGCTATG
TGTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.26	96.524	0.447