Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG429_RS05120 Genome accession   NZ_CP108131
Coordinates   1011838..1012503 (+) Length   221 a.a.
NCBI ID   WP_328924083.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00190     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1006838..1017503
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG429_RS05095 (OG429_05120) - 1007073..1008224 (-) 1152 WP_328924079.1 hypothetical protein -
  OG429_RS05100 (OG429_05125) - 1008705..1008864 (-) 160 Protein_1018 IS5/IS1182 family transposase -
  OG429_RS05105 (OG429_05130) - 1009054..1009788 (-) 735 WP_328924080.1 SDR family oxidoreductase -
  OG429_RS05110 (OG429_05135) - 1009916..1010506 (+) 591 WP_328924081.1 helix-turn-helix domain-containing protein -
  OG429_RS05115 (OG429_05140) - 1010636..1011841 (+) 1206 WP_328924082.1 sensor histidine kinase -
  OG429_RS05120 (OG429_05145) vraR 1011838..1012503 (+) 666 WP_328924083.1 response regulator transcription factor Regulator
  OG429_RS05125 (OG429_05150) - 1012732..1013022 (+) 291 WP_328924084.1 SHOCT domain-containing protein -
  OG429_RS05130 (OG429_05155) - 1013019..1013828 (+) 810 WP_328924085.1 ABC transporter ATP-binding protein -
  OG429_RS05135 (OG429_05160) - 1013825..1016395 (+) 2571 WP_328924086.1 FtsX-like permease family protein -
  OG429_RS05140 (OG429_05165) - 1016672..1016920 (-) 249 WP_328924087.1 hypothetical protein -
  OG429_RS05145 (OG429_05170) - 1016969..1017457 (-) 489 WP_328924088.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23976.81 Da        Isoelectric Point: 4.7928

>NTDB_id=654632 OG429_RS05120 WP_328924083.1 1011838..1012503(+) (vraR) [Streptomyces sp. NBC_00190]
MIRVLLADDQLLVRAGFRALLDAQSDIEVAGEAADGDEAVRLVRELRPDVVLMDIRMPVLDGLAATRLITGDGEFAAVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVEGDALLSPGVTRRLIAEFAARSKQPATAAELGRLTERER
EVMALVGMGLSNEEIARRLVVSPLTAKTHVSRAMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=654632 OG429_RS05120 WP_328924083.1 1011838..1012503(+) (vraR) [Streptomyces sp. NBC_00190]
GTGATCCGCGTACTGCTCGCCGACGACCAGCTTCTCGTGCGGGCCGGGTTCCGGGCACTGCTCGACGCGCAGTCCGACAT
CGAGGTGGCGGGTGAGGCGGCCGACGGCGACGAGGCGGTGCGGCTGGTGCGGGAGCTGCGCCCCGACGTCGTGCTCATGG
ACATCCGGATGCCGGTGCTCGACGGGCTGGCCGCCACCCGCCTGATCACCGGGGACGGGGAGTTCGCCGCGGTCAAGGTC
GTCATGCTCACCACCTTCGAGCTCGACGAGTACGTCTTCGAGGCGATCCGGTCCGGTGCCTCGGGTTTCCTGGTCAAGGA
CACCGAGCCGGAGGAACTGCTGCGCGCGGTCCGGGCGGTGGTGGAGGGCGACGCGCTGCTGTCCCCGGGAGTGACCCGCC
GTCTCATCGCGGAGTTCGCGGCCCGTTCGAAGCAGCCCGCCACCGCCGCGGAGCTGGGGCGGCTGACGGAGCGGGAGCGG
GAGGTGATGGCGCTGGTCGGCATGGGCCTGTCCAACGAGGAGATCGCCCGCCGCCTGGTCGTCAGCCCGCTCACCGCGAA
GACCCACGTCAGCCGGGCGATGGTCAAGCTCGGCGCCCGGGACCGGGCCCAACTGGTGGTCCTGGCCTACGAGTCCGGGC
TGGTCAGGCCCGGCTGGCTCGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.07

97.285

0.38
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.371