Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT93_RS37380 Genome accession   NZ_CP108130
Coordinates   8209046..8209726 (+) Length   226 a.a.
NCBI ID   WP_406278521.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00191     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8204046..8214726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT93_RS37360 (OHT93_37310) - 8204362..8204856 (+) 495 WP_406278515.1 hypothetical protein -
  OHT93_RS37365 (OHT93_37315) - 8205422..8206036 (+) 615 WP_406280145.1 hypothetical protein -
  OHT93_RS37370 (OHT93_37320) - 8206026..8206343 (-) 318 Protein_7386 ISAzo13-like element transposase-related protein -
  OHT93_RS37375 (OHT93_37325) - 8206587..8209049 (+) 2463 WP_406278518.1 histidine kinase -
  OHT93_RS37380 (OHT93_37330) vraR 8209046..8209726 (+) 681 WP_406278521.1 response regulator Regulator
  OHT93_RS37385 (OHT93_37335) - 8209973..8210122 (+) 150 WP_406278524.1 hypothetical protein -
  OHT93_RS37390 (OHT93_37340) - 8210283..8211692 (+) 1410 WP_406269631.1 IS1380 family transposase -
  OHT93_RS37395 (OHT93_37345) - 8211909..8212409 (+) 501 WP_406278527.1 GNAT family N-acetyltransferase -
  OHT93_RS37400 (OHT93_37350) - 8212414..8213289 (-) 876 WP_406278530.1 IS5 family transposase -
  OHT93_RS37405 (OHT93_37355) - 8213335..8213724 (-) 390 WP_406278533.1 hypothetical protein -
  OHT93_RS37410 - 8213709..8213930 (+) 222 Protein_7394 alpha/beta hydrolase -
  OHT93_RS37415 (OHT93_37360) - 8213974..8214345 (+) 372 WP_406278536.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24320.96 Da        Isoelectric Point: 4.9502

>NTDB_id=654626 OHT93_RS37380 WP_406278521.1 8209046..8209726(+) (vraR) [Streptomyces sp. NBC_00191]
MTIRVVIADDQAMVREAFSVLLDAQPDIEVITTAVDGLEAVAKAEELRPDVIVMDIRMPGLNGIDATRQITAQADLPTKI
LVLTTFNLDEYVYEALRAGASGFLLKDASGVQLAEAVRTVSAGEALLSPEITKRLITEFSRLSSSSSAKPPAHVRVDGLT
NRETEVLTLVAQGLSNAEIAGKLVVAEQTIKTHMGSILHKLQLRDRTQAAVFAYETGLVARGRTNL

Nucleotide


Download         Length: 681 bp        

>NTDB_id=654626 OHT93_RS37380 WP_406278521.1 8209046..8209726(+) (vraR) [Streptomyces sp. NBC_00191]
ATGACGATTCGAGTGGTGATCGCCGACGACCAGGCGATGGTCCGCGAAGCCTTCTCGGTGCTTCTCGACGCCCAGCCCGA
CATCGAAGTGATCACGACCGCCGTGGACGGCCTGGAAGCCGTCGCCAAGGCCGAAGAACTACGCCCCGACGTGATCGTCA
TGGACATCCGGATGCCCGGACTGAACGGCATCGACGCCACTCGCCAGATCACCGCGCAGGCCGACCTGCCCACCAAGATC
CTGGTCCTGACCACCTTCAACCTCGACGAGTACGTGTACGAAGCGCTGCGTGCCGGTGCCAGCGGATTTCTCCTCAAAGA
CGCCTCGGGAGTCCAACTGGCCGAAGCCGTACGCACCGTGTCCGCCGGCGAAGCTCTGCTGTCTCCGGAGATCACCAAGC
GGCTCATCACCGAGTTCTCCCGCCTGAGCAGCTCGAGCTCGGCGAAGCCACCCGCCCACGTACGGGTCGACGGGCTCACC
AACCGCGAAACCGAGGTACTGACGCTCGTCGCCCAAGGGCTTTCCAACGCGGAGATCGCCGGCAAGCTCGTCGTCGCCGA
ACAGACCATCAAGACCCACATGGGCAGCATCCTGCACAAGCTCCAGCTGCGAGACCGCACCCAGGCAGCCGTCTTCGCCT
ACGAGACGGGCCTGGTCGCCCGAGGCCGCACCAACCTGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(158-213)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.273

97.345

0.412
  degU Bacillus subtilis subsp. subtilis str. 168

39.286

99.115

0.389