Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT93_RS20570 Genome accession   NZ_CP108130
Coordinates   4534022..4534681 (+) Length   219 a.a.
NCBI ID   WP_406271266.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00191     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4529022..4539681
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT93_RS20550 (OHT93_20495) kynU 4529341..4530534 (+) 1194 WP_406271253.1 kynureninase -
  OHT93_RS20555 (OHT93_20500) - 4530836..4531723 (+) 888 WP_406271256.1 alpha/beta hydrolase -
  OHT93_RS20560 (OHT93_20505) - 4531775..4532608 (+) 834 WP_406271259.1 NAD(P)H-binding protein -
  OHT93_RS20565 (OHT93_20510) - 4532682..4534025 (+) 1344 WP_406271263.1 sensor histidine kinase -
  OHT93_RS20570 (OHT93_20515) vraR 4534022..4534681 (+) 660 WP_406271266.1 response regulator Regulator
  OHT93_RS20575 (OHT93_20520) - 4534729..4535931 (+) 1203 WP_406271269.1 cytochrome P450 -
  OHT93_RS20580 (OHT93_20525) - 4536142..4536864 (+) 723 WP_406271272.1 hypothetical protein -
  OHT93_RS20585 (OHT93_20530) - 4536968..4537804 (-) 837 WP_406271275.1 diacylglycerol kinase -
  OHT93_RS20590 (OHT93_20535) - 4537958..4539241 (+) 1284 WP_405600275.1 adenylosuccinate synthase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23591.30 Da        Isoelectric Point: 4.8202

>NTDB_id=654586 OHT93_RS20570 WP_406271266.1 4534022..4534681(+) (vraR) [Streptomyces sp. NBC_00191]
MTIRVLIVDDQIMVREGFSVLLNAMPDIEVVGEAVNGREAVARVAELAPDVVLMDIRMPELNGIEATREIVAAHADSKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPTVTRRLITEFSKLSQTPRPPALAQVGDLTERE
TEVLVLIAQGLSNAEIASHLVVAESTIKTHVSRVLVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 660 bp        

>NTDB_id=654586 OHT93_RS20570 WP_406271266.1 4534022..4534681(+) (vraR) [Streptomyces sp. NBC_00191]
ATGACGATCCGCGTCCTCATCGTCGACGACCAGATCATGGTCCGCGAGGGCTTCTCGGTCCTGCTGAACGCGATGCCCGA
CATCGAGGTCGTCGGCGAGGCCGTCAACGGCCGCGAGGCGGTCGCCAGGGTCGCCGAGCTCGCCCCCGACGTCGTCCTCA
TGGACATCCGTATGCCGGAGCTGAACGGCATCGAGGCGACCCGCGAGATCGTCGCGGCGCACGCCGATTCCAAGGTGCTG
GTGCTGACCACCTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGCGCGGGAGCCTCCGGCTTCCTGCTGAAGGACGC
GTCGGCACGCCAACTGGCCGACGGCGTACGGGTGGTGGCAGCCGGCGAGGCACTGCTCGCCCCGACGGTGACGCGCCGCC
TGATCACGGAGTTCTCCAAGCTCTCCCAGACCCCGCGACCGCCCGCGCTGGCGCAGGTCGGCGACCTGACGGAACGCGAG
ACGGAGGTCCTTGTGCTGATCGCGCAGGGCCTTTCGAACGCGGAGATCGCCTCGCATCTGGTGGTCGCCGAGTCGACGAT
CAAGACGCATGTGAGCCGGGTGCTGGTGAAGCTGGGGCTGCGGGACCGGACGCAGGCGGCGGTGTTCGCGTACGAGGCGA
GGCTGGTCACGCCCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Bacterial regulatory proteins, luxR family (GerE)

(156-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.907

98.63

0.443
  degU Bacillus subtilis subsp. subtilis str. 168

41.935

99.087

0.416