Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT93_RS05360 Genome accession   NZ_CP108130
Coordinates   1167368..1168018 (+) Length   216 a.a.
NCBI ID   WP_406264707.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00191     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1162368..1173018
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT93_RS05335 (OHT93_05295) mug 1163296..1163847 (+) 552 WP_406279215.1 G/U mismatch-specific DNA glycosylase -
  OHT93_RS05340 (OHT93_05300) - 1163893..1164312 (-) 420 WP_266488289.1 hypothetical protein -
  OHT93_RS05345 (OHT93_05305) - 1164353..1165096 (-) 744 WP_406264701.1 ABC transporter permease -
  OHT93_RS05350 (OHT93_05310) - 1165100..1166044 (-) 945 WP_406264703.1 ABC transporter ATP-binding protein -
  OHT93_RS05355 (OHT93_05315) - 1166152..1167363 (+) 1212 WP_406264705.1 sensor histidine kinase -
  OHT93_RS05360 (OHT93_05320) vraR 1167368..1168018 (+) 651 WP_406264707.1 response regulator Regulator
  OHT93_RS05365 (OHT93_05325) - 1168139..1169296 (+) 1158 WP_406264709.1 ROK family transcriptional regulator -
  OHT93_RS05370 (OHT93_05330) - 1169361..1170125 (-) 765 WP_406264711.1 GntR family transcriptional regulator -
  OHT93_RS05375 (OHT93_05335) - 1170374..1171258 (-) 885 WP_406264713.1 RNA polymerase sigma-70 factor -
  OHT93_RS05380 (OHT93_05340) - 1171432..1172262 (+) 831 WP_406264715.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 22909.48 Da        Isoelectric Point: 4.7361

>NTDB_id=654553 OHT93_RS05360 WP_406264707.1 1167368..1168018(+) (vraR) [Streptomyces sp. NBC_00191]
MPVTVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAADGAAVIPLVRQLRPDVVAMDVRMPLLDGIEATRAVVRTVQDPPKI
LVVTTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLVAEGESLLFPAAVRALAAEYGNNAARAAMERAALTEREAAV
LRLMARGLSNAEIAAELVVGTETVKSHVSAVLGKLGARDRTQAVIAAYESGFVAPA

Nucleotide


Download         Length: 651 bp        

>NTDB_id=654553 OHT93_RS05360 WP_406264707.1 1167368..1168018(+) (vraR) [Streptomyces sp. NBC_00191]
ATGCCGGTTACCGTTCTTCTGGTCGACGACGAACCCCTGGTCCGTGCGGGGCTGCGCGCGGTGCTCGAGGCGCAGCCCGA
TATCGAGGTGGTGGGTGAGGCCGCCGACGGAGCCGCAGTGATTCCGCTGGTACGGCAGCTGCGTCCCGATGTGGTGGCGA
TGGACGTGCGGATGCCGCTGCTCGACGGCATCGAGGCGACCCGGGCAGTGGTGCGCACGGTGCAGGATCCGCCCAAGATC
CTTGTCGTGACGACCTTCGAGAACGACGAGTACGTGTACGAAGCGCTGCGCGCCGGGGCGGACGGCTTCTTGCTCAAGCG
CGCCCGCCCTGCGGAGATCGTGCACGCGGTACGGCTCGTCGCGGAGGGAGAGTCGCTGTTGTTCCCGGCTGCGGTGCGCG
CCTTGGCCGCCGAGTACGGGAACAACGCCGCCCGCGCGGCGATGGAGCGGGCGGCGCTCACCGAACGGGAGGCGGCCGTG
TTGCGGCTGATGGCCCGTGGGCTGTCCAACGCGGAGATCGCTGCCGAGCTCGTCGTCGGCACGGAGACGGTGAAGTCCCA
TGTCAGCGCGGTGCTCGGCAAGTTGGGGGCGCGAGACCGCACCCAGGCGGTCATCGCCGCGTACGAGTCCGGTTTCGTGG
CCCCCGCCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-206)

Response regulator receiver domain (Response_reg)

(5-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.395

99.537

0.412
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.37