Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT93_RS04670 Genome accession   NZ_CP108130
Coordinates   1030020..1030685 (-) Length   221 a.a.
NCBI ID   WP_406264495.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00191     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1025020..1035685
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT93_RS04645 (OHT93_04600) - 1025574..1026806 (+) 1233 WP_406264489.1 MFS transporter -
  OHT93_RS04650 (OHT93_04605) - 1026973..1027716 (+) 744 WP_406279195.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OHT93_RS04655 (OHT93_04610) - 1027735..1028133 (-) 399 WP_266488044.1 MarR family winged helix-turn-helix transcriptional regulator -
  OHT93_RS04660 (OHT93_04615) - 1028221..1029699 (+) 1479 WP_406264491.1 MFS transporter -
  OHT93_RS04665 (OHT93_04620) - 1029775..1030059 (+) 285 WP_406264493.1 DUF6332 family protein -
  OHT93_RS04670 (OHT93_04625) vraR 1030020..1030685 (-) 666 WP_406264495.1 response regulator Regulator
  OHT93_RS04675 (OHT93_04630) - 1030682..1031917 (-) 1236 WP_406264497.1 sensor histidine kinase -
  OHT93_RS04680 (OHT93_04635) - 1032004..1032705 (-) 702 WP_406264499.1 TetR/AcrR family transcriptional regulator -
  OHT93_RS04685 (OHT93_04640) - 1032833..1033282 (+) 450 WP_406264501.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OHT93_RS04690 (OHT93_04645) - 1033457..1034710 (-) 1254 WP_406264503.1 geranylgeranyl reductase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24200.92 Da        Isoelectric Point: 4.6067

>NTDB_id=654551 OHT93_RS04670 WP_406264495.1 1030020..1030685(-) (vraR) [Streptomyces sp. NBC_00191]
MIRVLLADDQLLVRAGFRALLDAQRDIEVAGEAADGEEAVRLVRELRPDVVLMDIRMPELDGLAATRKITEDEQLGEVKV
VMLTTFELDEYVFDAIRSGASGFLVKDTEPEELLRAVRAVVQGDALLSPGVTRRLIAEFAARSKAPTDAEGLGELTERER
EVMALVGIGLSNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=654551 OHT93_RS04670 WP_406264495.1 1030020..1030685(-) (vraR) [Streptomyces sp. NBC_00191]
GTGATCCGCGTACTGCTCGCCGACGACCAGCTGCTCGTGAGGGCAGGCTTCCGCGCGCTGCTCGATGCCCAGCGGGACAT
CGAGGTGGCGGGCGAGGCGGCCGACGGCGAGGAGGCGGTACGGCTGGTGCGTGAACTGCGCCCCGACGTCGTGCTGATGG
ACATCCGGATGCCGGAGCTCGACGGTCTCGCCGCCACTCGGAAAATCACCGAGGACGAGCAGCTCGGGGAGGTGAAGGTG
GTGATGCTGACCACCTTCGAGCTCGACGAGTACGTCTTCGATGCGATCCGCTCCGGAGCCTCGGGATTCCTGGTGAAGGA
CACGGAGCCGGAGGAACTGCTGCGTGCGGTACGGGCGGTGGTGCAGGGCGACGCTCTGCTCTCCCCGGGCGTGACGCGCC
GTCTGATCGCGGAGTTCGCGGCTCGCTCCAAGGCACCCACGGACGCCGAGGGCCTTGGCGAACTCACCGAACGGGAGCGG
GAGGTGATGGCCCTCGTCGGCATCGGTCTGTCGAACGAGGAGATCGCCCGCAGACTCGTGGTCAGCCCGCTCACCGCCAA
GACGCATGTGAGCCGCACGATGGTCAAGCTCGGCGCCCGCGACCGGGCGCAACTGGTCGTGCTGGCCTACGAGTCGGGGT
TGGTGCGCCCGGGCTGGCTCGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.605

97.285

0.376
  degU Bacillus subtilis subsp. subtilis str. 168

36

100

0.367