Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHU08_RS09370 Genome accession   NZ_CP108128
Coordinates   2138495..2139136 (-) Length   213 a.a.
NCBI ID   WP_081223646.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00197     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2133495..2144136
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHU08_RS09340 (OHU08_09335) - 2134039..2135001 (-) 963 WP_081223641.1 SPFH domain-containing protein -
  OHU08_RS09345 (OHU08_09340) - 2135132..2135566 (-) 435 WP_164371033.1 NfeD family protein -
  OHU08_RS09350 (OHU08_09345) - 2135662..2136453 (-) 792 WP_164371032.1 ABC transporter ATP-binding protein -
  OHU08_RS09355 (OHU08_09350) - 2136575..2137363 (+) 789 WP_406377710.1 hypothetical protein -
  OHU08_RS09360 (OHU08_09355) - 2137603..2137842 (-) 240 WP_081223644.1 chaplin -
  OHU08_RS09365 (OHU08_09360) - 2138037..2138282 (-) 246 WP_351493547.1 chaplin -
  OHU08_RS09370 (OHU08_09365) vraR 2138495..2139136 (-) 642 WP_081223646.1 response regulator transcription factor Regulator
  OHU08_RS09375 (OHU08_09370) - 2139129..2140296 (-) 1168 Protein_1856 GAF domain-containing sensor histidine kinase -
  OHU08_RS09380 (OHU08_09375) - 2140517..2141212 (+) 696 WP_406380472.1 SDR family NAD(P)-dependent oxidoreductase -
  OHU08_RS09385 (OHU08_09380) - 2141209..2142333 (+) 1125 WP_164371027.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OHU08_RS09390 (OHU08_09385) - 2142636..2143379 (+) 744 WP_081223650.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22886.23 Da        Isoelectric Point: 5.1526

>NTDB_id=654482 OHU08_RS09370 WP_081223646.1 2138495..2139136(-) (vraR) [Streptomyces sp. NBC_00197]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEASDGAEGVARAEELKPDVVLMDVKMPGMDGIDALRKLRELANPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLSQEEANTGQGRGGSLTEREREVL
VLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRNGIAG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=654482 OHU08_RS09370 WP_081223646.1 2138495..2139136(-) (vraR) [Streptomyces sp. NBC_00197]
GTGGCTGACGCAATCAAGGTGCTGCTCGTCGACGACCACCAGGTCGTCCGCCGGGGCCTGCGCACCTTCCTCGAGGTGCA
GGACGACATCGAGGTCGTCGGAGAGGCGTCCGACGGCGCCGAGGGAGTCGCCCGCGCCGAGGAGCTGAAGCCCGACGTCG
TCCTGATGGACGTGAAGATGCCGGGCATGGACGGCATCGACGCGCTGCGCAAGCTCCGCGAACTCGCCAACCCCGCCCGC
GTGTTGATCGTCACCAGCTTCACCGAGCAGCGCACGGTGGTGCCCGCCCTGCGCGCGGGCGCCGCCGGGTACGTGTACAA
GGACGTGGACCCCGACGCGCTGGCCGGCGCCATCCGCTCCGTCCACGCGGGGCACATCCTCCTGCAACCCGAGGTCGCGG
GCGCCCTGTTGTCCCAGGAGGAGGCGAACACGGGCCAGGGGAGAGGCGGTTCGCTCACCGAGCGGGAACGCGAGGTGCTC
GTGCTGATCGCGGACGGCCGCTCCAACCGGGAGATCGCCCGCGCCCTGGTGCTCTCCGAGAAGACGGTGAAGACCCACGT
CTCGAACATCCTGATGAAGCTCGACCTCGCCGACCGCACCCAGGCCGCCCTCTGGGCCGTCAGGAACGGCATCGCGGGCT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.024

99.061

0.446
  degU Bacillus subtilis subsp. subtilis str. 168

38.462

100

0.399