Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG975_RS10755 Genome accession   NZ_CP108126
Coordinates   2331817..2332458 (-) Length   213 a.a.
NCBI ID   WP_330303574.1    Uniprot ID   A0ABW2VPD9
Organism   Streptomyces sp. NBC_00203     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2326817..2337458
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG975_RS10725 (OG975_10675) - 2327341..2327844 (+) 504 WP_406328900.1 HNH endonuclease -
  OG975_RS10730 (OG975_10680) - 2327970..2328905 (-) 936 WP_327427672.1 SPFH domain-containing protein -
  OG975_RS10735 (OG975_10685) - 2329036..2329470 (-) 435 WP_406328901.1 NfeD family protein -
  OG975_RS10740 (OG975_10690) - 2329565..2330356 (-) 792 WP_406328902.1 ABC transporter ATP-binding protein -
  OG975_RS10745 (OG975_10695) - 2330478..2331266 (+) 789 WP_330303572.1 hypothetical protein -
  OG975_RS10750 (OG975_10700) - 2331366..2331611 (-) 246 WP_406328903.1 chaplin -
  OG975_RS10755 (OG975_10705) vraR 2331817..2332458 (-) 642 WP_330303574.1 response regulator transcription factor Regulator
  OG975_RS10760 (OG975_10710) - 2332451..2333602 (-) 1152 WP_406328904.1 GAF domain-containing sensor histidine kinase -
  OG975_RS10765 (OG975_10715) - 2333790..2334485 (+) 696 WP_406328905.1 SDR family NAD(P)-dependent oxidoreductase -
  OG975_RS10770 (OG975_10720) - 2334482..2335567 (+) 1086 WP_406328906.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OG975_RS10775 (OG975_10725) - 2335867..2336616 (+) 750 WP_406328907.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22911.24 Da        Isoelectric Point: 5.3758

>NTDB_id=654396 OG975_RS10755 WP_330303574.1 2331817..2332458(-) (vraR) [Streptomyces sp. NBC_00203]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEASDGAEGIARAEELKPDVVLMDVKMPGMDGIEALRKLRELANPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLSQEEANSGQGRGGSLTEREREVL
TLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGVAG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=654396 OG975_RS10755 WP_330303574.1 2331817..2332458(-) (vraR) [Streptomyces sp. NBC_00203]
GTGGCTGACGCAATCAAGGTGCTGCTCGTCGACGACCACCAAGTGGTCCGCCGGGGTCTGCGCACCTTCCTCGAAGTACA
GGACGACATCGAGGTCGTGGGAGAGGCGTCCGACGGCGCCGAAGGGATCGCCCGCGCCGAGGAGTTGAAGCCCGACGTCG
TCCTCATGGACGTCAAGATGCCGGGCATGGACGGTATCGAGGCGCTGCGCAAGCTCCGCGAACTCGCCAACCCCGCGCGC
GTGCTGATCGTCACCAGCTTCACCGAGCAGCGCACGGTCGTCCCCGCCCTGCGCGCGGGCGCCGCCGGATATGTGTACAA
GGACGTGGACCCCGACGCCCTCGCCGGCGCCATTCGCTCCGTGCACGCCGGACACATCCTGCTGCAGCCCGAGGTCGCGG
GCGCGCTGCTGTCCCAGGAGGAGGCCAACTCGGGCCAGGGGAGAGGCGGTTCACTCACCGAGCGGGAGCGTGAGGTGCTC
ACCCTGATCGCGGACGGCCGCTCCAACCGCGAGATCGCCCGCGCGCTCGTCCTCTCCGAGAAGACCGTCAAGACGCATGT
CTCGAACATCCTGATGAAACTCGACCTGGCGGACCGGACCCAGGCCGCGCTCTGGGCCGTACGACATGGAGTGGCAGGCT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.445

99.061

0.46
  degU Bacillus subtilis subsp. subtilis str. 168

38.462

100

0.399