Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG975_RS05910 Genome accession   NZ_CP108126
Coordinates   1257848..1258513 (-) Length   221 a.a.
NCBI ID   WP_406327937.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00203     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1252848..1263513
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG975_RS05885 (OG975_05840) - 1252857..1253591 (+) 735 WP_406327930.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OG975_RS05890 (OG975_05845) - 1253634..1254047 (-) 414 WP_406327932.1 MarR family winged helix-turn-helix transcriptional regulator -
  OG975_RS05895 (OG975_05850) - 1254133..1255635 (+) 1503 WP_327426736.1 MFS transporter -
  OG975_RS05900 (OG975_05855) - 1255892..1256557 (+) 666 WP_406327934.1 RNA polymerase sigma factor -
  OG975_RS05905 (OG975_05860) - 1256554..1257609 (+) 1056 WP_406327936.1 CU044_5270 family protein -
  OG975_RS05910 (OG975_05865) vraR 1257848..1258513 (-) 666 WP_406327937.1 response regulator Regulator
  OG975_RS05915 (OG975_05870) - 1258510..1259754 (-) 1245 WP_406327939.1 sensor histidine kinase -
  OG975_RS05920 (OG975_05875) - 1259836..1260564 (-) 729 WP_406327941.1 TetR/AcrR family transcriptional regulator -
  OG975_RS05925 (OG975_05880) - 1260712..1261161 (+) 450 WP_406327943.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OG975_RS05930 (OG975_05885) - 1261180..1262385 (-) 1206 WP_406327944.1 geranylgeranyl reductase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24103.85 Da        Isoelectric Point: 4.7333

>NTDB_id=654386 OG975_RS05910 WP_406327937.1 1257848..1258513(-) (vraR) [Streptomyces sp. NBC_00203]
MIRVLLADDQSLVRAGFKALLDAQPDIEVAGEAADGEEAVRKVRELRPDVVLMDIRMPLLDGLAATRRLTDDADLKDVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVEGDALLSPGVTRRLISEFAARSKEPATAASLAELTERER
EVMALVGIGLSNDEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=654386 OG975_RS05910 WP_406327937.1 1257848..1258513(-) (vraR) [Streptomyces sp. NBC_00203]
GTGATCCGCGTACTGCTCGCCGACGACCAGTCACTGGTCAGGGCAGGCTTCAAGGCACTGCTCGACGCGCAGCCGGACAT
CGAGGTGGCCGGCGAGGCGGCCGACGGCGAGGAGGCGGTCCGCAAGGTGCGCGAACTGCGCCCCGACGTCGTCCTGATGG
ACATCCGCATGCCCCTGCTCGACGGCCTCGCCGCGACCCGTCGCCTCACCGACGACGCGGACTTGAAGGACGTCAAGGTG
GTCATGCTCACCACCTTCGAACTCGACGAGTACGTCTTCGAAGCGATCCGTTCCGGAGCCTCCGGCTTCCTGGTCAAGGA
CACCGAGCCGGAGGAACTCCTGCGCGCGGTACGGGCGGTGGTCGAGGGGGACGCCCTGCTCTCCCCGGGGGTGACGCGCC
GGCTGATCTCCGAGTTCGCGGCTCGTTCCAAGGAGCCCGCGACCGCCGCCTCCCTCGCCGAACTCACCGAACGGGAACGG
GAGGTGATGGCCCTGGTCGGCATCGGCCTCTCGAACGACGAGATCGCCCGCCGTCTCGTCGTCAGCCCGCTCACGGCGAA
GACCCACGTCAGCCGGACCATGGTCAAGCTGGGCGCCCGCGACCGGGCCCAACTGGTCGTGCTGGCCTACGAGTCGGGGT
TGGTGCGGCCGGGCTGGCTGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.889

97.738

0.38
  degU Bacillus subtilis subsp. subtilis str. 168

37.333

100

0.38