Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG911_RS34435 Genome accession   NZ_CP108123
Coordinates   7474596..7475240 (+) Length   214 a.a.
NCBI ID   WP_267005898.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00208     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7469596..7480240
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG911_RS34415 (OG911_34470) - 7470385..7471134 (-) 750 WP_326631340.1 transglycosylase SLT domain-containing protein -
  OG911_RS34420 (OG911_34475) - 7471421..7472524 (-) 1104 WP_326814192.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OG911_RS34425 (OG911_34480) - 7472521..7473264 (-) 744 WP_326631342.1 SDR family NAD(P)-dependent oxidoreductase -
  OG911_RS34430 (OG911_34485) - 7473458..7474603 (+) 1146 WP_326814191.1 GAF domain-containing sensor histidine kinase -
  OG911_RS34435 (OG911_34490) vraR 7474596..7475240 (+) 645 WP_267005898.1 response regulator transcription factor Regulator
  OG911_RS34440 (OG911_34495) - 7475387..7475635 (+) 249 WP_030974440.1 chaplin family protein -
  OG911_RS34445 (OG911_34500) - 7475802..7476584 (-) 783 WP_326602892.1 hypothetical protein -
  OG911_RS34450 (OG911_34505) - 7476708..7477505 (+) 798 WP_267005900.1 ABC transporter ATP-binding protein -
  OG911_RS34455 (OG911_34510) - 7477560..7477988 (+) 429 WP_267005901.1 NfeD family protein -
  OG911_RS34460 (OG911_34515) - 7478115..7479044 (+) 930 WP_030920228.1 SPFH domain-containing protein -
  OG911_RS34465 (OG911_34520) - 7479213..7479719 (-) 507 WP_030920231.1 HNH endonuclease -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23051.37 Da        Isoelectric Point: 5.1683

>NTDB_id=654364 OG911_RS34435 WP_267005898.1 7474596..7475240(+) (vraR) [Streptomyces sp. NBC_00208]
MADKIIRVLLVDDHQVVRRGLRTFLEIQDDIEVVGEAADGAEGVARSEELRPDVVLMDIKMPGTDGIEALRKLRELENPA
KVLIVTSFTEQRTVVPALRAGASGYVYKDVDPDALAGAIRSVYAGHVLLQPEVAGALLAQEDAGGGTGRGSTLTEREREV
LGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLSDRTQAALWAVRHGVAG

Nucleotide


Download         Length: 645 bp        

>NTDB_id=654364 OG911_RS34435 WP_267005898.1 7474596..7475240(+) (vraR) [Streptomyces sp. NBC_00208]
GTGGCTGACAAGATCATCAGGGTGCTGCTGGTCGACGACCACCAGGTGGTCCGCCGCGGTCTGCGTACGTTCCTGGAGAT
CCAGGACGACATAGAGGTAGTCGGCGAGGCGGCCGACGGCGCGGAGGGCGTGGCCAGGAGCGAGGAGCTGCGCCCCGACG
TGGTCCTGATGGACATCAAGATGCCGGGCACGGACGGCATCGAGGCGCTCCGCAAGCTCCGGGAGCTGGAGAACCCGGCC
AAGGTGCTGATCGTCACCAGCTTCACCGAGCAGCGCACGGTGGTCCCTGCCCTGCGCGCGGGCGCCTCCGGTTACGTGTA
CAAGGACGTCGACCCGGACGCACTGGCCGGCGCCATCCGCTCGGTGTACGCGGGCCATGTCCTGCTCCAGCCGGAGGTCG
CCGGAGCCCTGCTCGCCCAGGAGGACGCCGGCGGCGGTACGGGCCGGGGGAGCACTCTCACCGAACGGGAGCGGGAAGTA
CTGGGCCTGATCGCCGACGGCCGTTCCAACCGTGAGATCGCCAGGGCGCTGGTCCTCTCCGAGAAGACCGTCAAGACGCA
CGTCTCGAACATTCTGATGAAGCTGGATCTGTCGGACCGAACCCAGGCCGCCCTCTGGGCCGTCCGACATGGGGTGGCAG
GCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-207)

Response regulator receiver domain (Response_reg)

(8-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.928

96.729

0.435
  degU Bacillus subtilis subsp. subtilis str. 168

39.367

100

0.407