Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG911_RS22340 Genome accession   NZ_CP108123
Coordinates   4841193..4841855 (-) Length   220 a.a.
NCBI ID   WP_267003650.1    Uniprot ID   A0ABV2UEL0
Organism   Streptomyces sp. NBC_00208     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4836193..4846855
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG911_RS22315 (OG911_22355) - 4836203..4836475 (+) 273 WP_267003640.1 DUF1876 domain-containing protein -
  OG911_RS22320 (OG911_22360) - 4836520..4836942 (-) 423 WP_326608527.1 MarR family transcriptional regulator -
  OG911_RS22325 (OG911_22365) - 4837168..4838091 (+) 924 WP_328920476.1 ABC transporter ATP-binding protein -
  OG911_RS22330 (OG911_22370) - 4838088..4839689 (+) 1602 WP_327239998.1 ABC transporter permease -
  OG911_RS22335 (OG911_22375) - 4839926..4841155 (-) 1230 WP_326604971.1 cytochrome P450 -
  OG911_RS22340 (OG911_22380) vraR 4841193..4841855 (-) 663 WP_267003650.1 response regulator transcription factor Regulator
  OG911_RS22345 (OG911_22385) - 4841852..4843165 (-) 1314 WP_328920477.1 histidine kinase -
  OG911_RS22350 (OG911_22390) - 4843297..4844172 (-) 876 WP_326814762.1 alpha/beta hydrolase -
  OG911_RS22355 (OG911_22395) kynU 4844282..4845520 (-) 1239 WP_326814761.1 kynureninase -
  OG911_RS22360 (OG911_22400) - 4845513..4846361 (-) 849 WP_326814760.1 tryptophan 2,3-dioxygenase family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23521.32 Da        Isoelectric Point: 4.9350

>NTDB_id=654340 OG911_RS22340 WP_267003650.1 4841193..4841855(-) (vraR) [Streptomyces sp. NBC_00208]
MNDIRVLIVDDQMMVREGFSVLLGAMPGIEVVGEAVDGRQAIAQAAALRPDVVLMDIRMPELNGIEATREIVANDAAAKV
LVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPTVTKRLITEFSRLAGAPRPPALARIGDLTER
ETEVLVLIAQGLSNAEIASHLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPA

Nucleotide


Download         Length: 663 bp        

>NTDB_id=654340 OG911_RS22340 WP_267003650.1 4841193..4841855(-) (vraR) [Streptomyces sp. NBC_00208]
ATGAACGACATCCGTGTCCTGATCGTCGACGATCAGATGATGGTCCGTGAGGGCTTCTCGGTGCTCCTGGGGGCGATGCC
GGGCATCGAGGTCGTCGGCGAGGCCGTCGACGGCCGGCAGGCCATCGCCCAGGCCGCCGCGCTGCGGCCCGACGTGGTGC
TGATGGACATCCGGATGCCGGAGCTCAACGGCATCGAGGCGACCCGTGAGATCGTCGCGAACGACGCGGCCGCCAAGGTG
CTCGTGCTGACCACGTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGCGCCGGGGCGTCCGGGTTTCTGCTGAAGGA
CGCCTCCGCCCGCCAGCTCGCCGACGGGGTACGGGTGGTGGCGGCCGGGGAGGCGCTGCTGGCGCCGACCGTCACGAAGC
GGCTGATCACCGAGTTCTCCCGGCTCGCCGGGGCCCCGCGGCCGCCCGCGCTCGCCCGGATCGGCGATCTGACGGAGCGT
GAGACGGAGGTGCTCGTACTCATCGCGCAGGGCCTGTCGAACGCGGAGATCGCCTCGCACCTGGTGGTCGCCGAGTCCAC
CATCAAGACGCATGTGAGCCGCATCCTGGTGAAGCTGGGGCTGCGGGACCGCACGCAGGCGGCGGTGTTCGCGTACGAGG
CGCGGCTGGTCACCCCGGCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-115)

Bacterial regulatory proteins, luxR family (GerE)

(157-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.86

97.273

0.436
  degU Bacillus subtilis subsp. subtilis str. 168

42.727

100

0.427