Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG729_RS34725 Genome accession   NZ_CP108120
Coordinates   7662585..7663250 (+) Length   221 a.a.
NCBI ID   WP_405809897.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00210     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7657585..7668250
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG729_RS34705 (OG729_34690) - 7658502..7659719 (+) 1218 WP_360883703.1 geranylgeranyl reductase family protein -
  OG729_RS34710 (OG729_34695) - 7659933..7660382 (-) 450 WP_360883700.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OG729_RS34715 (OG729_34700) - 7660529..7661263 (+) 735 WP_405809895.1 TetR/AcrR family transcriptional regulator -
  OG729_RS34720 (OG729_34705) - 7661359..7662588 (+) 1230 WP_405809896.1 sensor histidine kinase -
  OG729_RS34725 (OG729_34710) vraR 7662585..7663250 (+) 666 WP_405809897.1 response regulator Regulator
  OG729_RS34730 (OG729_34715) - 7663211..7663501 (-) 291 WP_405809899.1 DUF6332 family protein -
  OG729_RS34735 (OG729_34720) - 7663577..7665055 (-) 1479 WP_360875666.1 MFS transporter -
  OG729_RS34740 (OG729_34725) - 7665142..7665543 (+) 402 WP_405809900.1 MarR family winged helix-turn-helix transcriptional regulator -
  OG729_RS34745 (OG729_34730) - 7665558..7666301 (-) 744 WP_405809902.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OG729_RS34750 (OG729_34735) - 7666324..7666671 (-) 348 WP_405809903.1 SCO4225 family membrane protein -
  OG729_RS34755 (OG729_34740) - 7666668..7667963 (-) 1296 WP_405809905.1 MFS transporter -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24095.94 Da        Isoelectric Point: 4.9005

>NTDB_id=654218 OG729_RS34725 WP_405809897.1 7662585..7663250(+) (vraR) [Streptomyces sp. NBC_00210]
MIRVLLADDQLLVRAGFRALLDAQQDIEAVGEAADGEEAVRLVAELRPDVVLMDIRMPLLDGLAATRRITEDERLSGVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPAELLRAVRAVVHGDALLSPGVTRRLIAEFAARSKAPSDAQCLAELTERER
EVMALVGIGLSNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=654218 OG729_RS34725 WP_405809897.1 7662585..7663250(+) (vraR) [Streptomyces sp. NBC_00210]
GTGATCCGGGTACTGCTCGCCGATGACCAGCTGCTGGTCAGGGCGGGGTTCAGGGCGCTGCTCGATGCCCAGCAGGACAT
CGAGGCGGTGGGCGAGGCGGCCGACGGTGAGGAGGCGGTGCGGCTGGTGGCCGAACTGCGCCCCGACGTCGTGCTGATGG
ACATCCGTATGCCGCTGCTGGACGGCCTCGCCGCGACCCGCCGGATCACCGAGGACGAGCGGCTGAGCGGAGTGAAGGTG
GTCATGCTGACCACCTTCGAGCTCGACGAGTACGTCTTCGAGGCGATCCGCTCCGGCGCCTCGGGCTTCCTGGTGAAGGA
CACCGAGCCGGCGGAACTGCTGCGTGCGGTACGGGCGGTGGTGCACGGGGACGCGCTGCTTTCCCCGGGCGTGACGCGCC
GCCTGATCGCGGAGTTCGCCGCACGCTCCAAGGCTCCCAGCGATGCCCAATGCCTGGCCGAGCTCACCGAACGCGAGCGT
GAAGTGATGGCCCTGGTCGGCATCGGTCTGTCCAACGAGGAGATCGCCCGCCGTCTTGTGGTCAGCCCGCTCACCGCGAA
GACCCATGTGAGCCGCACCATGGTGAAGCTGGGCGCTCGCGACCGGGCCCAACTGGTGGTGCTGGCCTACGAGTCGGGGT
TGGTGCGGCCCGGCTGGCTGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.14

97.285

0.371
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.371