Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG729_RS12465 Genome accession   NZ_CP108120
Coordinates   2790831..2791481 (+) Length   216 a.a.
NCBI ID   WP_360872191.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00210     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2785831..2796481
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG729_RS12435 (OG729_12435) - 2785948..2786586 (-) 639 WP_405806019.1 TetR/AcrR family transcriptional regulator -
  OG729_RS12440 (OG729_12440) - 2786666..2787448 (+) 783 WP_405806021.1 ABC transporter ATP-binding protein -
  OG729_RS12445 (OG729_12445) - 2787457..2788212 (+) 756 WP_405806022.1 ABC transporter permease -
  OG729_RS12450 (OG729_12450) - 2788226..2788798 (+) 573 WP_405806024.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
  OG729_RS12455 (OG729_12455) - 2788896..2789486 (-) 591 WP_405806025.1 hypothetical protein -
  OG729_RS12460 (OG729_12460) - 2789629..2790834 (+) 1206 WP_405806027.1 sensor histidine kinase -
  OG729_RS12465 (OG729_12465) vraR 2790831..2791481 (+) 651 WP_360872191.1 response regulator transcription factor Regulator
  OG729_RS12470 (OG729_12470) - 2791640..2793502 (+) 1863 WP_405806028.1 glycosyl hydrolase family 18 protein -
  OG729_RS12475 (OG729_12475) - 2793568..2794017 (-) 450 WP_360872197.1 DUF2550 domain-containing protein -
  OG729_RS12480 (OG729_12480) - 2794157..2794528 (-) 372 WP_360872200.1 F0F1 ATP synthase subunit epsilon -
  OG729_RS12485 (OG729_12485) atpD 2794714..2796156 (-) 1443 WP_360872203.1 F0F1 ATP synthase subunit beta -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23056.72 Da        Isoelectric Point: 4.8509

>NTDB_id=654167 OG729_RS12465 WP_360872191.1 2790831..2791481(+) (vraR) [Streptomyces sp. NBC_00210]
MTIRVLVAEDQSAVRAGLVLILGSAPDIEVVGEAADGEEAVRRARELRPDLVLMDIQMPRLDGVSATRQVVDAQLADVLV
LTTFDLDEYVFGALRAGAAGFLLKNTDAADLLEAVRTVARGEGLIAPAVTRRLIAEFAAPTPVRPRDASELAILDALTRR
EREVLSCLGEGMSNAEIAGRLAMAEATVKTHVSRLLGKLKLRSRVQAAVLAQELGI

Nucleotide


Download         Length: 651 bp        

>NTDB_id=654167 OG729_RS12465 WP_360872191.1 2790831..2791481(+) (vraR) [Streptomyces sp. NBC_00210]
ATGACGATCCGGGTACTGGTCGCGGAGGACCAGAGCGCCGTACGGGCCGGTCTGGTCCTCATCCTGGGCAGCGCGCCGGA
CATCGAGGTCGTCGGCGAGGCGGCGGACGGTGAGGAAGCGGTGCGGCGCGCCCGCGAACTGCGCCCCGATCTCGTGCTGA
TGGATATTCAGATGCCGCGCCTGGACGGGGTTTCGGCCACTCGGCAGGTCGTCGACGCACAGCTCGCCGATGTGCTCGTC
CTGACCACGTTCGATCTGGACGAGTATGTCTTCGGGGCGCTGCGGGCCGGGGCCGCGGGCTTCTTGCTGAAGAACACCGA
TGCCGCGGATCTGCTGGAGGCGGTGCGCACGGTGGCGCGCGGCGAGGGTCTGATCGCGCCGGCCGTCACCCGCCGGCTGA
TCGCTGAGTTCGCGGCGCCCACTCCCGTACGGCCCCGGGACGCGTCCGAACTCGCGATCCTCGATGCACTCACCCGCCGG
GAACGCGAGGTGCTGTCGTGTCTCGGCGAGGGGATGTCGAACGCCGAGATCGCGGGTCGGCTGGCGATGGCCGAGGCGAC
GGTGAAGACCCATGTGAGCCGTCTCCTCGGCAAGCTGAAGCTCCGCAGCCGCGTGCAAGCGGCCGTGCTGGCCCAGGAGT
TGGGCATCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-211)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.453

98.148

0.417
  degU Bacillus subtilis subsp. subtilis str. 168

40.271

100

0.412