Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG820_RS12190 Genome accession   NZ_CP108118
Coordinates   2716318..2717025 (+) Length   235 a.a.
NCBI ID   WP_327278808.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00211     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2711318..2722025
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG820_RS12165 (OG820_12160) - 2711378..2712067 (-) 690 WP_406387003.1 DUF4190 domain-containing protein -
  OG820_RS12170 (OG820_12165) - 2712178..2713203 (+) 1026 WP_327278811.1 adenosine deaminase -
  OG820_RS12175 (OG820_12170) - 2713226..2713933 (+) 708 WP_327278810.1 glycerophosphodiester phosphodiesterase -
  OG820_RS12180 (OG820_12175) - 2713933..2715177 (+) 1245 WP_406389132.1 sensor histidine kinase -
  OG820_RS12185 (OG820_12180) - 2715133..2716254 (-) 1122 WP_327280728.1 IS630 family transposase -
  OG820_RS12190 (OG820_12185) vraR 2716318..2717025 (+) 708 WP_327278808.1 response regulator transcription factor Regulator
  OG820_RS12195 (OG820_12190) - 2717172..2718395 (+) 1224 WP_406387004.1 serine hydrolase domain-containing protein -
  OG820_RS12200 (OG820_12195) - 2718362..2718862 (-) 501 WP_328763868.1 hypothetical protein -
  OG820_RS12205 (OG820_12200) - 2718960..2720138 (-) 1179 WP_327278805.1 spermidine/putrescine ABC transporter substrate-binding protein -
  OG820_RS12210 (OG820_12205) - 2720243..2721682 (-) 1440 WP_327278804.1 gamma-aminobutyraldehyde dehydrogenase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 24631.13 Da        Isoelectric Point: 4.9844

>NTDB_id=654082 OG820_RS12190 WP_327278808.1 2716318..2717025(+) (vraR) [Streptomyces sp. NBC_00211]
MTIRVVVADDQELVRSGFAMILDVQEDIEVVAEVGDGAAAVAAVRELRPDVALLDVRMPVLDGIEACRTISAGTSCRTVI
LTTFDSDEYVYEALHAGASGFLLKDVRRDDLVHAVRVVAAGESLLAPSVARRLIEEYTAATARPAGALSAQRLEVLTARE
RETLLHLGRGLSNAEIAGALVVSEHTVKSHVGHVLAKLGLRDRIQAVICAYETGLIAAGTGAAGAAGSGVSPSRE

Nucleotide


Download         Length: 708 bp        

>NTDB_id=654082 OG820_RS12190 WP_327278808.1 2716318..2717025(+) (vraR) [Streptomyces sp. NBC_00211]
TTGACGATCCGTGTGGTGGTGGCGGACGACCAGGAACTGGTGCGCAGCGGGTTCGCGATGATCCTGGACGTGCAGGAGGA
CATCGAGGTCGTCGCGGAGGTGGGGGACGGGGCGGCGGCGGTGGCCGCGGTGCGGGAGCTGCGGCCGGACGTGGCGCTGC
TGGACGTCCGGATGCCGGTGCTCGACGGGATCGAGGCGTGCCGGACGATCTCGGCCGGGACCTCGTGCCGGACGGTGATC
CTGACGACCTTCGACTCGGACGAGTACGTGTACGAGGCGCTGCACGCGGGGGCGAGCGGGTTCCTGCTGAAGGACGTGCG
GCGGGACGATCTGGTGCATGCCGTACGGGTGGTGGCGGCGGGCGAGTCACTGCTGGCGCCTTCGGTGGCGCGGCGGCTGA
TCGAGGAGTACACGGCGGCTACGGCGCGGCCGGCGGGGGCGCTGTCGGCGCAGCGGCTGGAGGTGCTGACGGCGCGGGAG
CGGGAGACGCTTCTGCACCTGGGGCGGGGGCTGTCGAACGCGGAGATCGCGGGCGCGCTGGTGGTGAGCGAGCACACGGT
GAAGTCCCATGTGGGCCATGTGCTGGCGAAGCTCGGGCTGCGGGACCGGATCCAGGCGGTGATCTGCGCGTACGAGACGG
GTCTCATCGCGGCCGGGACGGGGGCCGCGGGCGCGGCCGGCTCTGGGGTATCTCCCTCCCGGGAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-210)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.553

92.34

0.374
  degU Bacillus subtilis subsp. subtilis str. 168

38.117

94.894

0.362