Detailed information NTG0654061

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: MAK48_RS18310
• Genome accession: NZ_CP091872
• Coordinates: 3537893..3539050 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus sp. Man122
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3532893..3544050

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MAK48_RS18280 (MAK48_18280)	-	3533146..3533565 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
MAK48_RS18285 (MAK48_18285)	comFC	3533639..3534361 (-)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
MAK48_RS18290 (MAK48_18290)	comFB	3534325..3534621 (-)	297	WP_003227989.1	late competence protein ComFB	-
MAK48_RS18295 (MAK48_18295)	comFA	3534681..3536072 (-)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
MAK48_RS18300 (MAK48_18300)	-	3536178..3537023 (-)	846	WP_003244125.1	DegV family protein	-
MAK48_RS18305 (MAK48_18305)	degU	3537121..3537810 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
MAK48_RS18310 (MAK48_18310)	degS	3537893..3539050 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
MAK48_RS18315 (MAK48_18315)	-	3539267..3539920 (+)	654	WP_003227979.1	YigZ family protein	-
MAK48_RS18320 (MAK48_18320)	tagV	3539920..3541095 (+)	1176	WP_003244117.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
MAK48_RS18325 (MAK48_18325)	-	3541168..3542244 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
MAK48_RS18330 (MAK48_18330)	-	3542389..3543582 (-)	1194	WP_003243252.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=654061 MAK48_RS18310 WP_003227983.1 3537893..3539050(-) (degS) [Bacillus sp. Man122]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=654061 MAK48_RS18310 WP_003227983.1 3537893..3539050(-) (degS) [Bacillus sp. Man122]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1