Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   MAK48_RS16345 Genome accession   NZ_CP091872
Coordinates   3145356..3146000 (-) Length   214 a.a.
NCBI ID   WP_003220716.1    Uniprot ID   -
Organism   Bacillus sp. Man122     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3140356..3151000
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MAK48_RS16310 (MAK48_16310) - 3141548..3141979 (+) 432 WP_003228819.1 Na(+)/H(+) antiporter subunit B -
  MAK48_RS16315 (MAK48_16315) - 3141979..3142320 (+) 342 WP_003220730.1 Na(+)/H(+) antiporter subunit C -
  MAK48_RS16320 (MAK48_16320) - 3142313..3143794 (+) 1482 WP_003228817.1 Na+/H+ antiporter subunit D -
  MAK48_RS16325 (MAK48_16325) - 3143800..3144276 (+) 477 WP_003228815.1 Na+/H+ antiporter subunit E -
  MAK48_RS16330 (MAK48_16330) - 3144276..3144560 (+) 285 WP_003228814.1 Na(+)/H(+) antiporter subunit F1 -
  MAK48_RS16335 (MAK48_16335) mnhG 3144544..3144918 (+) 375 WP_003228812.1 monovalent cation/H(+) antiporter subunit G -
  MAK48_RS16340 (MAK48_16340) - 3144957..3145337 (-) 381 WP_003228810.1 hotdog fold thioesterase -
  MAK48_RS16345 (MAK48_16345) comA 3145356..3146000 (-) 645 WP_003220716.1 two-component system response regulator ComA Regulator
  MAK48_RS16350 (MAK48_16350) comP 3146081..3148378 (-) 2298 WP_032730345.1 histidine kinase Regulator
  MAK48_RS16355 (MAK48_16355) comX 3148386..3148547 (-) 162 WP_003228803.1 competence pheromone ComX -
  MAK48_RS16360 (MAK48_16360) - 3148562..3149422 (-) 861 WP_029318489.1 polyprenyl synthetase family protein -
  MAK48_RS16365 (MAK48_16365) degQ 3149607..3149747 (-) 141 WP_003220708.1 degradation enzyme regulation protein DegQ Regulator
  MAK48_RS16370 (MAK48_16370) - 3149969..3150094 (+) 126 WP_003228793.1 hypothetical protein -
  MAK48_RS16375 (MAK48_16375) - 3150208..3150576 (+) 369 WP_014477834.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24128.51 Da        Isoelectric Point: 4.6857

>NTDB_id=654053 MAK48_RS16345 WP_003220716.1 3145356..3146000(-) (comA) [Bacillus sp. Man122]
MKKILVIDDHPAVMEGTKTILETDSNLSVDCLSPEPSEQFIKQHDFSSYDLILMDLNLGGEVNGMELSKQILQENPHCKI
IVYTGYEVEDYFEEAIRAGLHGAISKTESKEKITQYIYHVLNGEILVDFAYFKQLMTQQKTKPAPSSQKEQDVLTPRECL
ILQEVEKGFTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDGVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=654053 MAK48_RS16345 WP_003220716.1 3145356..3146000(-) (comA) [Bacillus sp. Man122]
ATGAAAAAGATACTAGTGATTGATGACCATCCGGCTGTCATGGAAGGCACCAAGACAATTTTGGAAACGGATTCGAATTT
GTCTGTTGATTGTCTCAGTCCTGAACCGAGCGAACAGTTTATCAAGCAGCATGATTTCTCGTCATATGATCTCATTTTAA
TGGATCTGAATCTAGGCGGCGAGGTCAATGGGATGGAGCTTTCTAAACAGATTTTACAAGAGAATCCTCATTGTAAAATT
ATCGTGTATACCGGTTATGAGGTCGAGGATTATTTCGAGGAAGCGATTCGTGCGGGTCTGCACGGTGCCATCAGCAAAAC
GGAATCTAAAGAAAAGATCACCCAATACATATACCACGTACTCAACGGAGAAATTTTAGTCGATTTTGCTTACTTTAAAC
AGCTGATGACTCAGCAAAAAACAAAGCCGGCTCCTTCCTCTCAAAAAGAACAAGATGTGCTCACACCTAGAGAATGCCTG
ATTCTTCAAGAAGTTGAAAAGGGATTTACAAACCAAGAAATCGCAGATGCCCTTCATTTAAGCAAGCGGTCCATTGAATA
CAGCTTGACATCGATTTTCAATAAGCTGAATGTCGGTTCACGGACGGAAGCGGTTTTGATTGCGAAATCAGACGGTGTAC
TTTAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-208)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

100

100

1