Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA17_RS27535 Genome accession   NZ_CP108115
Coordinates   6036876..6037559 (-) Length   227 a.a.
NCBI ID   WP_053727186.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00212     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6031876..6042559
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA17_RS27515 (OHA17_27455) - 6032588..6033079 (+) 492 WP_406508794.1 MerR family transcriptional regulator -
  OHA17_RS27520 (OHA17_27460) - 6033086..6034114 (+) 1029 WP_406508795.1 aldo/keto reductase -
  OHA17_RS27525 (OHA17_27465) - 6034135..6035337 (-) 1203 WP_406508796.1 acyltransferase -
  OHA17_RS27530 (OHA17_27470) - 6035334..6036377 (-) 1044 WP_406508797.1 alpha/beta hydrolase -
  OHA17_RS27535 (OHA17_27475) vraR 6036876..6037559 (-) 684 WP_053727186.1 response regulator transcription factor Regulator
  OHA17_RS27540 (OHA17_27480) - 6037569..6038846 (-) 1278 WP_406508798.1 sensor histidine kinase -
  OHA17_RS27545 (OHA17_27485) - 6038935..6039801 (-) 867 WP_406508799.1 DUF4429 domain-containing protein -
  OHA17_RS27550 (OHA17_27490) - 6039919..6041130 (-) 1212 WP_053727183.1 alpha/beta hydrolase -
  OHA17_RS27555 (OHA17_27495) - 6041289..6041921 (-) 633 WP_053727196.1 TetR family transcriptional regulator -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 24180.00 Da        Isoelectric Point: 5.3712

>NTDB_id=654038 OHA17_RS27535 WP_053727186.1 6036876..6037559(-) (vraR) [Streptomyces sp. NBC_00212]
MTIRVIIVDDQAMVRAGFAALLSAQADIDVVGEAPDGRQGVEVARSTHPDVVLMDVRMPEMDGLAAAREILDPPVGVVHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLIGAVRVVAAGEALLAPSVTRRLIADFAAQRPAPRKGTAALRLNG
LTPRETEVLELIARGLSNQEIAGRLVLAEQTVKTHIGRVLAKLDLRDRAQAVIFAYEAGVVRPGDPG

Nucleotide


Download         Length: 684 bp        

>NTDB_id=654038 OHA17_RS27535 WP_053727186.1 6036876..6037559(-) (vraR) [Streptomyces sp. NBC_00212]
TTGACCATCCGCGTGATCATCGTCGACGACCAGGCCATGGTGCGGGCGGGGTTCGCCGCGCTGCTCTCGGCGCAGGCCGA
CATCGACGTGGTGGGCGAGGCGCCCGACGGCCGCCAGGGGGTCGAGGTGGCCCGCTCCACCCACCCGGACGTGGTCCTGA
TGGACGTCCGCATGCCCGAGATGGACGGGCTCGCCGCGGCCCGCGAGATCCTGGACCCGCCGGTGGGAGTCGTCCACCGG
CCCAAGGTGCTGATGCTGACCACCTTCGACGTCGACGACTACGTGTACGAGGCGCTGCGCGCGGGGGCATCCGGGTTCCT
CCTGAAGGACGCGCCGCCCGCCGACCTGATCGGGGCGGTACGGGTCGTGGCGGCGGGAGAAGCCCTCCTCGCCCCCTCCG
TGACGCGGCGGCTCATCGCGGACTTCGCGGCGCAGCGGCCGGCGCCGCGCAAGGGGACGGCGGCGTTGCGTCTCAACGGG
CTGACGCCCAGGGAGACGGAAGTGCTGGAACTGATCGCCCGGGGCCTCTCGAACCAGGAGATCGCGGGGCGGCTGGTGCT
GGCCGAGCAGACCGTGAAGACGCATATCGGCCGGGTCCTGGCGAAGCTGGACCTCCGGGACCGGGCCCAGGCGGTGATCT
TCGCCTACGAGGCGGGCGTGGTCCGACCTGGCGACCCGGGCTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(161-215)

Response regulator receiver domain (Response_reg)

(5-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.256

98.238

0.405
  degU Bacillus subtilis subsp. subtilis str. 168

36.087

100

0.366